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GLE1 (GLE1, RNA export mediator)

Identity

Alias_namesGLE1L
LCCS1
GLE1 (yeast homolog)-like, RNA export mediator
GLE1 RNA export mediator-like (yeast)
GLE1 RNA export mediator (yeast)
lethal congenital contracture syndrome 1
GLE1 RNA export mediator homolog (yeast)
Alias_symbol (synonym)hGLE1
Other aliasLCCS
HGNC (Hugo) GLE1
LocusID (NCBI) 2733
Atlas_Id 55781
Location 9q34.11  [Link to chromosome band 9q34]
Location_base_pair Starts at 131266971 and ends at 131304580 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
GLE1 (9q34.11) / ODF2 (9q34.11)LOC284276 () / GLE1 (9q34.11)PBX3 (9q33.3) / GLE1 (9q34.11)
SPTAN1 (9q34.11) / GLE1 (9q34.11)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GLE1   4315
LRG (Locus Reference Genomic)LRG_484
Cards
Entrez_Gene (NCBI)GLE1  2733  GLE1, RNA export mediator
AliasesGLE1L; LCCS; LCCS1; hGLE1
GeneCards (Weizmann)GLE1
Ensembl hg19 (Hinxton)ENSG00000119392 [Gene_View]  chr9:131266971-131304580 [Contig_View]  GLE1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000119392 [Gene_View]  chr9:131266971-131304580 [Contig_View]  GLE1 [Vega]
ICGC DataPortalENSG00000119392
TCGA cBioPortalGLE1
AceView (NCBI)GLE1
Genatlas (Paris)GLE1
WikiGenes2733
SOURCE (Princeton)GLE1
Genetics Home Reference (NIH)GLE1
Genomic and cartography
GoldenPath hg19 (UCSC)GLE1  -     chr9:131266971-131304580 +  9q34.11   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)GLE1  -     9q34.11   [Description]    (hg38-Dec_2013)
EnsemblGLE1 - 9q34.11 [CytoView hg19]  GLE1 - 9q34.11 [CytoView hg38]
Mapping of homologs : NCBIGLE1 [Mapview hg19]  GLE1 [Mapview hg38]
OMIM253310   603371   611890   
Gene and transcription
Genbank (Entrez)AA806769 AF058922 AK001767 AK074801 AK222842
RefSeq transcript (Entrez)NM_001003722 NM_001499
RefSeq genomic (Entrez)NC_000009 NC_018920 NG_012073 NT_008470 NW_004929366
Consensus coding sequences : CCDS (NCBI)GLE1
Cluster EST : UnigeneHs.522418 [ NCBI ]
CGAP (NCI)Hs.522418
Alternative Splicing GalleryENSG00000119392
Gene ExpressionGLE1 [ NCBI-GEO ]   GLE1 [ EBI - ARRAY_EXPRESS ]   GLE1 [ SEEK ]   GLE1 [ MEM ]
Gene Expression Viewer (FireBrowse)GLE1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2733
GTEX Portal (Tissue expression)GLE1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ53GS7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ53GS7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ53GS7
Splice isoforms : SwissVarQ53GS7
PhosPhoSitePlusQ53GS7
Domains : Interpro (EBI)GLE1   
Domain families : Pfam (Sanger)GLE1 (PF07817)   
Domain families : Pfam (NCBI)pfam07817   
Conserved Domain (NCBI)GLE1
DMDM Disease mutations2733
Blocks (Seattle)GLE1
SuperfamilyQ53GS7
Human Protein AtlasENSG00000119392
Peptide AtlasQ53GS7
HPRD04536
IPIIPI00301647   IPI00411438   IPI01012645   
Protein Interaction databases
DIP (DOE-UCLA)Q53GS7
IntAct (EBI)Q53GS7
FunCoupENSG00000119392
BioGRIDGLE1
STRING (EMBL)GLE1
ZODIACGLE1
Ontologies - Pathways
QuickGOQ53GS7
Ontology : AmiGOinositol hexakisphosphate binding  protein binding  phospholipid binding  extracellular space  nuclear pore  cytoplasm  cytoplasm  plasma membrane  mRNA export from nucleus  regulation of translational initiation  regulation of translational termination  protein transport  membrane  poly(A)+ mRNA export from nucleus  translation initiation factor binding  identical protein binding  nuclear pore cytoplasmic filaments  
Ontology : EGO-EBIinositol hexakisphosphate binding  protein binding  phospholipid binding  extracellular space  nuclear pore  cytoplasm  cytoplasm  plasma membrane  mRNA export from nucleus  regulation of translational initiation  regulation of translational termination  protein transport  membrane  poly(A)+ mRNA export from nucleus  translation initiation factor binding  identical protein binding  nuclear pore cytoplasmic filaments  
NDEx NetworkGLE1
Atlas of Cancer Signalling NetworkGLE1
Wikipedia pathwaysGLE1
Orthology - Evolution
OrthoDB2733
GeneTree (enSembl)ENSG00000119392
Phylogenetic Trees/Animal Genes : TreeFamGLE1
HOVERGENQ53GS7
HOGENOMQ53GS7
Homologs : HomoloGeneGLE1
Homology/Alignments : Family Browser (UCSC)GLE1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGLE1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GLE1
dbVarGLE1
ClinVarGLE1
1000_GenomesGLE1 
Exome Variant ServerGLE1
ExAC (Exome Aggregation Consortium)GLE1 (select the gene name)
Genetic variants : HAPMAP2733
Genomic Variants (DGV)GLE1 [DGVbeta]
DECIPHER (Syndromes)9:131266971-131304580  ENSG00000119392
CONAN: Copy Number AnalysisGLE1 
Mutations
ICGC Data PortalGLE1 
TCGA Data PortalGLE1 
Broad Tumor PortalGLE1
OASIS PortalGLE1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGLE1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGLE1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GLE1
DgiDB (Drug Gene Interaction Database)GLE1
DoCM (Curated mutations)GLE1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GLE1 (select a term)
intoGenGLE1
Cancer3DGLE1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM253310    603371    611890   
Orphanet1660    10738   
MedgenGLE1
Genetic Testing Registry GLE1
NextProtQ53GS7 [Medical]
TSGene2733
GENETestsGLE1
Huge Navigator GLE1 [HugePedia]
snp3D : Map Gene to Disease2733
BioCentury BCIQGLE1
ClinGenGLE1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2733
Chemical/Pharm GKB GenePA28718
Clinical trialGLE1
Miscellaneous
canSAR (ICR)GLE1 (select the gene name)
Probes
Litterature
PubMed32 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGLE1
EVEXGLE1
GoPubMedGLE1
iHOPGLE1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:02:29 CEST 2017

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