GLI3 (GLI-Kruppel family member GLI3)

Identity

Other names	ACLS
	GCPS
	PAP-A
	PAPA
	PAPA1
	PAPB
	PHS
	PPDIV
HGNC	GLI3
Location	7p13
Location_base_pair	Starts at 41967073 and ends at 42243321 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	GLI3   4319
Entrez_Gene	GLI3  2737  GLI-Kruppel family member GLI3
	Cards
GeneCards	GLI3
Ensembl	GLI3 [Search_View]   ENSG00000106571 [Gene_View]
Genatlas	GLI3
GeneLynx	GLI3
eGenome	GLI3
euGene	2737
	Genomic and cartography
GoldenPath	GLI3  -  7p13   chr7:41967073-42243321 -  7p14.1   [Description]    (hg18-March_2006)
Ensembl	GLI3 - 7p14.1 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	GLI3
	Gene and transcription
Genbank	AA330409 [ ENTREZ ]
Genbank	AK308429 [ ENTREZ ]
Genbank	BC113616 [ ENTREZ ]
Genbank	BC117168 [ ENTREZ ]
Genbank	BF194991 [ ENTREZ ]
RefSeq	NM_000168 [ SRS ]    NM_000168 [ ENTREZ ]
RefSeq	AC_000050 [ SRS ]    AC_000050 [ ENTREZ ]
RefSeq	AC_000068 [ SRS ]    AC_000068 [ ENTREZ ]
RefSeq	AC_000139 [ SRS ]    AC_000139 [ ENTREZ ]
RefSeq	NC_000007 [ SRS ]    NC_000007 [ ENTREZ ]
RefSeq	NT_007819 [ SRS ]    NT_007819 [ ENTREZ ]
RefSeq	NT_079592 [ SRS ]    NT_079592 [ ENTREZ ]
RefSeq	NW_001839004 [ SRS ]    NW_001839004 [ ENTREZ ]
RefSeq	NW_923240 [ SRS ]    NW_923240 [ ENTREZ ]
AceView	GLI3 AceView - NCBI
Unigene	Hs.21509 [ SRS ]    Hs.21509 [ NCBI ]     HS21509 [ spliceNest ]
Fast-db	4273 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P10071 [ SRS]    P10071 [ EXPASY ]     P10071 [ INTERPRO ]     P10071 [ UNIPROT ]
Prosite	PS00028 ZINC_FINGER_C2H2_1 [ SRS ]    PS00028 ZINC_FINGER_C2H2_1 [ Expasy ]
Prosite	PS50157 ZINC_FINGER_C2H2_2 [ SRS ]    PS50157 ZINC_FINGER_C2H2_2 [ Expasy ]
Interpro	IPR007087 Znf_C2H2 [ SRS ]    IPR007087 Znf_C2H2 [ EBI ]
Interpro	IPR015880 Znf_C2H2-like [ SRS ]    IPR015880 Znf_C2H2-like [ EBI ]
Interpro	IPR013087 Znf_C2H2/integrase_DNA-bd [ SRS ]    IPR013087 Znf_C2H2/integrase_DNA-bd [ EBI ]
CluSTr	P10071
Pfam	PF00096 zf-C2H2 [ SRS ]    PF00096 zf-C2H2 [ Sanger ]    pfam00096 [ NCBI-CDD ]
Smart	SM00355 ZnF_C2H2 [EMBL]
Blocks	P10071
HPRD	01313
	Protein Interaction databases
DIP	P10071
IntAct	P10071
	Polymorphism : SNP, mutations, diseases
OMIM	146510;165240;174200;174700;175700;200990;241800    [ map ]
GENECLINICS	146510;165240;174200;174700;175700;200990;241800
SNP	GLI3 [dbSNP-NCBI]
SNP	NM_000168 [SNP-NCI]
SNP	GLI3 [GeneSNPs - Utah]  GLI3] [HGBASE - SRS]
HAPMAP	GLI3 [HAPMAP]
COSMIC	GLI3 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	GLI3
	General knowledge
Family Browser	GLI3 [UCSC Family Browser]
SOURCE	NM_000168
SMD	Hs.21509
SAGE	Hs.21509
GO	protein import into nucleus, translocation [Amigo]  protein import into nucleus, translocation
GO	metanephros development [Amigo]  metanephros development
GO	ureteric bud branching [Amigo]  ureteric bud branching
GO	chromatin binding [Amigo]  chromatin binding
GO	transcription factor activity [Amigo]  transcription factor activity
GO	protein binding [Amigo]  protein binding
GO	intracellular [Amigo]  intracellular
GO	nucleus [Amigo]  nucleus
GO	cytoplasm [Amigo]  cytoplasm
GO	regulation of transcription, DNA-dependent [Amigo]  regulation of transcription, DNA-dependent
GO	signal transduction [Amigo]  signal transduction
GO	smoothened signaling pathway [Amigo]  smoothened signaling pathway
GO	pattern specification process [Amigo]  pattern specification process
GO	hindgut morphogenesis [Amigo]  hindgut morphogenesis
GO	heart development [Amigo]  heart development
GO	zinc ion binding [Amigo]  zinc ion binding
GO	negative regulation of cell proliferation [Amigo]  negative regulation of cell proliferation
GO	anterior/posterior pattern formation [Amigo]  anterior/posterior pattern formation
GO	proximal/distal pattern formation [Amigo]  proximal/distal pattern formation
GO	negative regulation of transcription [Amigo]  negative regulation of transcription
GO	transcriptional repressor complex [Amigo]  transcriptional repressor complex
GO	spinal cord dorsal/ventral patterning [Amigo]  spinal cord dorsal/ventral patterning
GO	optic nerve morphogenesis [Amigo]  optic nerve morphogenesis
GO	smoothened signaling pathway involved in ventral spinal cord interneuron specification [Amigo]  smoothened signaling pathway involved in ventral spinal cord interneuron specification
GO	smoothened signaling pathway involved in spinal cord motor neuron cell fate specification [Amigo]  smoothened signaling pathway involved in spinal cord motor neuron cell fate specification
GO	neural tube development [Amigo]  neural tube development
GO	lung development [Amigo]  lung development
GO	embryonic limb morphogenesis [Amigo]  embryonic limb morphogenesis
GO	mammary gland development [Amigo]  mammary gland development
GO	forebrain development [Amigo]  forebrain development
GO	tube development [Amigo]  tube development
GO	odontogenesis of dentine-containing tooth [Amigo]  odontogenesis of dentine-containing tooth
GO	sequence-specific DNA binding [Amigo]  sequence-specific DNA binding
GO	negative regulation of cell differentiation [Amigo]  negative regulation of cell differentiation
GO	metal ion binding [Amigo]  metal ion binding
GO	embryonic gut morphogenesis [Amigo]  embryonic gut morphogenesis
GO	developmental growth [Amigo]  developmental growth
GO	camera-type eye morphogenesis [Amigo]  camera-type eye morphogenesis
GO	embryonic morphogenesis [Amigo]  embryonic morphogenesis
GO	anatomical structure formation [Amigo]  anatomical structure formation
GO	neuron fate commitment [Amigo]  neuron fate commitment
BIOCARTA	Sonic Hedgehog (Shh) Pathway    [Genes]
KEGG	Hedgehog signaling pathway
PubGene	GLI3
TreeFam	GLI3
CTD	2737 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	GLI3 Related clones (RZPD - Berlin)
	PubMed
PubMed	44 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 18 14:43:12 2008