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GLRA2 (glycine receptor alpha 2)

Identity

Alias_namesGLR
Other alias
HGNC (Hugo) GLRA2
LocusID (NCBI) 2742
Atlas_Id 56348
Location Xp22.2  [Link to chromosome band Xp22]
Location_base_pair Starts at 14529298 and ends at 14731811 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
LOC100506713 () / GLRA2 (Xp22.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GLRA2   4327
Cards
Entrez_Gene (NCBI)GLRA2  2742  glycine receptor alpha 2
AliasesGLR
GeneCards (Weizmann)GLRA2
Ensembl hg19 (Hinxton)ENSG00000101958 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000101958 [Gene_View]  chrX:14529298-14731811 [Contig_View]  GLRA2 [Vega]
ICGC DataPortalENSG00000101958
TCGA cBioPortalGLRA2
AceView (NCBI)GLRA2
Genatlas (Paris)GLRA2
WikiGenes2742
SOURCE (Princeton)GLRA2
Genetics Home Reference (NIH)GLRA2
Genomic and cartography
GoldenPath hg38 (UCSC)GLRA2  -     chrX:14529298-14731811 +  Xp22.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GLRA2  -     Xp22.2   [Description]    (hg19-Feb_2009)
EnsemblGLRA2 - Xp22.2 [CytoView hg19]  GLRA2 - Xp22.2 [CytoView hg38]
Mapping of homologs : NCBIGLRA2 [Mapview hg19]  GLRA2 [Mapview hg38]
OMIM305990   
Gene and transcription
Genbank (Entrez)AA081959 AK289561 AK297268 AK297304 AK312591
RefSeq transcript (Entrez)NM_001118885 NM_001118886 NM_001171942 NM_002063
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GLRA2
Cluster EST : UnigeneHs.2700 [ NCBI ]
CGAP (NCI)Hs.2700
Alternative Splicing GalleryENSG00000101958
Gene ExpressionGLRA2 [ NCBI-GEO ]   GLRA2 [ EBI - ARRAY_EXPRESS ]   GLRA2 [ SEEK ]   GLRA2 [ MEM ]
Gene Expression Viewer (FireBrowse)GLRA2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2742
GTEX Portal (Tissue expression)GLRA2
Protein : pattern, domain, 3D structure
UniProt/SwissProtP23416   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP23416  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP23416
Splice isoforms : SwissVarP23416
PhosPhoSitePlusP23416
Domaine pattern : Prosite (Expaxy)NEUROTR_ION_CHANNEL (PS00236)   
Domains : Interpro (EBI)GABAA/Glycine_rcpt    Glycine_rcpt_A    Glycine_rcpt_A2    Neur_chan_lig-bd    Neur_channel    Neurotrans-gated_channel_TM    Neurotransmitter_ion_chnl_CS   
Domain families : Pfam (Sanger)Neur_chan_LBD (PF02931)    Neur_chan_memb (PF02932)   
Domain families : Pfam (NCBI)pfam02931    pfam02932   
Conserved Domain (NCBI)GLRA2
DMDM Disease mutations2742
Blocks (Seattle)GLRA2
SuperfamilyP23416
Human Protein AtlasENSG00000101958
Peptide AtlasP23416
HPRD02379
IPIIPI00011566   IPI00220450   IPI00955489   IPI00643998   
Protein Interaction databases
DIP (DOE-UCLA)P23416
IntAct (EBI)P23416
FunCoupENSG00000101958
BioGRIDGLRA2
STRING (EMBL)GLRA2
ZODIACGLRA2
Ontologies - Pathways
QuickGOP23416
Ontology : AmiGOplasma membrane  integral component of plasma membrane  neuropeptide signaling pathway  glycine binding  extracellular-glycine-gated chloride channel activity  glycine-gated chloride ion channel activity  cell junction  ion transmembrane transport  ion transmembrane transport  chloride channel complex  cell projection  postsynaptic membrane  metal ion binding  synaptic transmission, glycinergic  excitatory postsynaptic potential  cellular response to amino acid stimulus  cellular response to zinc ion  cellular response to ethanol  chloride transmembrane transport  
Ontology : EGO-EBIplasma membrane  integral component of plasma membrane  neuropeptide signaling pathway  glycine binding  extracellular-glycine-gated chloride channel activity  glycine-gated chloride ion channel activity  cell junction  ion transmembrane transport  ion transmembrane transport  chloride channel complex  cell projection  postsynaptic membrane  metal ion binding  synaptic transmission, glycinergic  excitatory postsynaptic potential  cellular response to amino acid stimulus  cellular response to zinc ion  cellular response to ethanol  chloride transmembrane transport  
Pathways : KEGGNeuroactive ligand-receptor interaction   
NDEx NetworkGLRA2
Atlas of Cancer Signalling NetworkGLRA2
Wikipedia pathwaysGLRA2
Orthology - Evolution
OrthoDB2742
GeneTree (enSembl)ENSG00000101958
Phylogenetic Trees/Animal Genes : TreeFamGLRA2
HOVERGENP23416
HOGENOMP23416
Homologs : HomoloGeneGLRA2
Homology/Alignments : Family Browser (UCSC)GLRA2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGLRA2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GLRA2
dbVarGLRA2
ClinVarGLRA2
1000_GenomesGLRA2 
Exome Variant ServerGLRA2
ExAC (Exome Aggregation Consortium)GLRA2 (select the gene name)
Genetic variants : HAPMAP2742
Genomic Variants (DGV)GLRA2 [DGVbeta]
DECIPHERGLRA2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGLRA2 
Mutations
ICGC Data PortalGLRA2 
TCGA Data PortalGLRA2 
Broad Tumor PortalGLRA2
OASIS PortalGLRA2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGLRA2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGLRA2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
BioMutasearch GLRA2
DgiDB (Drug Gene Interaction Database)GLRA2
DoCM (Curated mutations)GLRA2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GLRA2 (select a term)
intoGenGLRA2
Cancer3DGLRA2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM305990   
Orphanet
MedgenGLRA2
Genetic Testing Registry GLRA2
NextProtP23416 [Medical]
TSGene2742
GENETestsGLRA2
Target ValidationGLRA2
Huge Navigator GLRA2 [HugePedia]
snp3D : Map Gene to Disease2742
BioCentury BCIQGLRA2
ClinGenGLRA2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2742
Chemical/Pharm GKB GenePA28728
Clinical trialGLRA2
Miscellaneous
canSAR (ICR)GLRA2 (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGLRA2
EVEXGLRA2
GoPubMedGLRA2
iHOPGLRA2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:09:59 CEST 2017

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