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GLRA3 (glycine receptor alpha 3)

Identity

Other alias-
HGNC (Hugo) GLRA3
LocusID (NCBI) 8001
Atlas_Id 63826
Location 4q34.1  [Link to chromosome band 4q34]
Location_base_pair Starts at 174642011 and ends at 174829315 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GLRA3   4328
Cards
Entrez_Gene (NCBI)GLRA3  8001  glycine receptor alpha 3
Aliases
GeneCards (Weizmann)GLRA3
Ensembl hg19 (Hinxton)ENSG00000145451 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000145451 [Gene_View]  chr4:174642011-174829315 [Contig_View]  GLRA3 [Vega]
ICGC DataPortalENSG00000145451
TCGA cBioPortalGLRA3
AceView (NCBI)GLRA3
Genatlas (Paris)GLRA3
WikiGenes8001
SOURCE (Princeton)GLRA3
Genetics Home Reference (NIH)GLRA3
Genomic and cartography
GoldenPath hg38 (UCSC)GLRA3  -     chr4:174642011-174829315 -  4q34.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GLRA3  -     4q34.1   [Description]    (hg19-Feb_2009)
EnsemblGLRA3 - 4q34.1 [CytoView hg19]  GLRA3 - 4q34.1 [CytoView hg38]
Mapping of homologs : NCBIGLRA3 [Mapview hg19]  GLRA3 [Mapview hg38]
OMIM600421   
Gene and transcription
Genbank (Entrez)AF018157 BC036086 BI600831 CV381684 DA409556
RefSeq transcript (Entrez)NM_001042543 NM_006529
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GLRA3
Cluster EST : UnigeneHs.413099 [ NCBI ]
CGAP (NCI)Hs.413099
Alternative Splicing GalleryENSG00000145451
Gene ExpressionGLRA3 [ NCBI-GEO ]   GLRA3 [ EBI - ARRAY_EXPRESS ]   GLRA3 [ SEEK ]   GLRA3 [ MEM ]
Gene Expression Viewer (FireBrowse)GLRA3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8001
GTEX Portal (Tissue expression)GLRA3
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75311   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75311  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75311
Splice isoforms : SwissVarO75311
PhosPhoSitePlusO75311
Domaine pattern : Prosite (Expaxy)NEUROTR_ION_CHANNEL (PS00236)   
Domains : Interpro (EBI)GABAA/Glycine_rcpt    Glycine_rcpt_A    Glycine_rcpt_A3    Neur_chan_lig-bd    Neur_channel    Neurotrans-gated_channel_TM    Neurotransmitter_ion_chnl_CS   
Domain families : Pfam (Sanger)Neur_chan_LBD (PF02931)    Neur_chan_memb (PF02932)   
Domain families : Pfam (NCBI)pfam02931    pfam02932   
Conserved Domain (NCBI)GLRA3
DMDM Disease mutations8001
Blocks (Seattle)GLRA3
PDB (SRS)5CFB    5TIN    5TIO   
PDB (PDBSum)5CFB    5TIN    5TIO   
PDB (IMB)5CFB    5TIN    5TIO   
PDB (RSDB)5CFB    5TIN    5TIO   
Structural Biology KnowledgeBase5CFB    5TIN    5TIO   
SCOP (Structural Classification of Proteins)5CFB    5TIN    5TIO   
CATH (Classification of proteins structures)5CFB    5TIN    5TIO   
SuperfamilyO75311
Human Protein AtlasENSG00000145451
Peptide AtlasO75311
HPRD02688
IPIIPI00025243   IPI00216193   
Protein Interaction databases
DIP (DOE-UCLA)O75311
IntAct (EBI)O75311
FunCoupENSG00000145451
BioGRIDGLRA3
STRING (EMBL)GLRA3
ZODIACGLRA3
Ontologies - Pathways
QuickGOO75311
Ontology : AmiGOplasma membrane  integral component of plasma membrane  integral component of plasma membrane  neuropeptide signaling pathway  glycine binding  extracellular-glycine-gated chloride channel activity  glycine-gated chloride channel complex  glycine-gated chloride ion channel activity  cell junction  dendrite  ion transmembrane transport  response to amino acid  perikaryon  postsynaptic membrane  metal ion binding  protein homooligomerization  synaptic transmission, glycinergic  excitatory postsynaptic potential  chloride transmembrane transport  
Ontology : EGO-EBIplasma membrane  integral component of plasma membrane  integral component of plasma membrane  neuropeptide signaling pathway  glycine binding  extracellular-glycine-gated chloride channel activity  glycine-gated chloride channel complex  glycine-gated chloride ion channel activity  cell junction  dendrite  ion transmembrane transport  response to amino acid  perikaryon  postsynaptic membrane  metal ion binding  protein homooligomerization  synaptic transmission, glycinergic  excitatory postsynaptic potential  chloride transmembrane transport  
Pathways : KEGGNeuroactive ligand-receptor interaction   
NDEx NetworkGLRA3
Atlas of Cancer Signalling NetworkGLRA3
Wikipedia pathwaysGLRA3
Orthology - Evolution
OrthoDB8001
GeneTree (enSembl)ENSG00000145451
Phylogenetic Trees/Animal Genes : TreeFamGLRA3
HOVERGENO75311
HOGENOMO75311
Homologs : HomoloGeneGLRA3
Homology/Alignments : Family Browser (UCSC)GLRA3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGLRA3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GLRA3
dbVarGLRA3
ClinVarGLRA3
1000_GenomesGLRA3 
Exome Variant ServerGLRA3
ExAC (Exome Aggregation Consortium)GLRA3 (select the gene name)
Genetic variants : HAPMAP8001
Genomic Variants (DGV)GLRA3 [DGVbeta]
DECIPHERGLRA3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGLRA3 
Mutations
ICGC Data PortalGLRA3 
TCGA Data PortalGLRA3 
Broad Tumor PortalGLRA3
OASIS PortalGLRA3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGLRA3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGLRA3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GLRA3
DgiDB (Drug Gene Interaction Database)GLRA3
DoCM (Curated mutations)GLRA3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GLRA3 (select a term)
intoGenGLRA3
Cancer3DGLRA3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600421   
Orphanet
MedgenGLRA3
Genetic Testing Registry GLRA3
NextProtO75311 [Medical]
TSGene8001
GENETestsGLRA3
Target ValidationGLRA3
Huge Navigator GLRA3 [HugePedia]
snp3D : Map Gene to Disease8001
BioCentury BCIQGLRA3
ClinGenGLRA3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8001
Chemical/Pharm GKB GenePA28729
Clinical trialGLRA3
Miscellaneous
canSAR (ICR)GLRA3 (select the gene name)
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGLRA3
EVEXGLRA3
GoPubMedGLRA3
iHOPGLRA3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 15:50:44 CEST 2017

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