Atlas of Genetics and Cytogenetics in Oncology and Haematology


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GLRX5 (glutaredoxin 5)

Identity

Alias_namesC14orf87
chromosome 14 open reading frame 87
glutaredoxin 5 homolog (S. cerevisiae)
Alias_symbol (synonym)PR01238
GRX5
Other aliasFLB4739
PRO1238
PRSA
HGNC (Hugo) GLRX5
LocusID (NCBI) 51218
Atlas_Id 63829
Location 14q32.13  [Link to chromosome band 14q32]
Location_base_pair Starts at 96001323 and ends at 96011055 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GLRX5   20134
Cards
Entrez_Gene (NCBI)GLRX5  51218  glutaredoxin 5
AliasesC14orf87; FLB4739; GRX5; PR01238; 
PRO1238; PRSA
GeneCards (Weizmann)GLRX5
Ensembl hg19 (Hinxton) [Gene_View]  chr14:96001323-96011055 [Contig_View]  GLRX5 [Vega]
Ensembl hg38 (Hinxton) [Gene_View]  chr14:96001323-96011055 [Contig_View]  GLRX5 [Vega]
TCGA cBioPortalGLRX5
AceView (NCBI)GLRX5
Genatlas (Paris)GLRX5
WikiGenes51218
SOURCE (Princeton)GLRX5
Genetics Home Reference (NIH)GLRX5
Genomic and cartography
GoldenPath hg19 (UCSC)GLRX5  -     chr14:96001323-96011055 +  14q32.13   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)GLRX5  -     14q32.13   [Description]    (hg38-Dec_2013)
EnsemblGLRX5 - 14q32.13 [CytoView hg19]  GLRX5 - 14q32.13 [CytoView hg38]
Mapping of homologs : NCBIGLRX5 [Mapview hg19]  GLRX5 [Mapview hg38]
OMIM205950   609588   
Gene and transcription
Genbank (Entrez)AB223038 AF113691 AI089763 BC023528 BC047680
RefSeq transcript (Entrez)NM_016417
RefSeq genomic (Entrez)NC_000014 NC_018925 NG_021217 NT_026437 NW_004929393
Consensus coding sequences : CCDS (NCBI)GLRX5
Cluster EST : UnigeneHs.744943 [ NCBI ]
CGAP (NCI)Hs.744943
Gene ExpressionGLRX5 [ NCBI-GEO ]   GLRX5 [ EBI - ARRAY_EXPRESS ]   GLRX5 [ SEEK ]   GLRX5 [ MEM ]
Gene Expression Viewer (FireBrowse)GLRX5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51218
GTEX Portal (Tissue expression)GLRX5
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86SX6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86SX6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86SX6
Splice isoforms : SwissVarQ86SX6
PhosPhoSitePlusQ86SX6
Domaine pattern : Prosite (Expaxy)GLUTAREDOXIN_2 (PS51354)   
Domains : Interpro (EBI)Glutaredoxin    Monothiol_GRX-rel    Thioredoxin-like_fold   
Domain families : Pfam (Sanger)Glutaredoxin (PF00462)   
Domain families : Pfam (NCBI)pfam00462   
Conserved Domain (NCBI)GLRX5
DMDM Disease mutations51218
Blocks (Seattle)GLRX5
PDB (SRS)2MMZ    2WUL   
PDB (PDBSum)2MMZ    2WUL   
PDB (IMB)2MMZ    2WUL   
PDB (RSDB)2MMZ    2WUL   
Structural Biology KnowledgeBase2MMZ    2WUL   
SCOP (Structural Classification of Proteins)2MMZ    2WUL   
CATH (Classification of proteins structures)2MMZ    2WUL   
SuperfamilyQ86SX6
Peptide AtlasQ86SX6
HPRD12659
IPIIPI00333763   IPI00009250   IPI01026297   
Protein Interaction databases
DIP (DOE-UCLA)Q86SX6
IntAct (EBI)Q86SX6
BioGRIDGLRX5
STRING (EMBL)GLRX5
ZODIACGLRX5
Ontologies - Pathways
QuickGOQ86SX6
Ontology : AmiGOnucleus  mitochondrion  mitochondrion  electron carrier activity  protein disulfide oxidoreductase activity  hemopoiesis  cell redox homeostasis  metal ion binding  2 iron, 2 sulfur cluster binding  oxidation-reduction process  
Ontology : EGO-EBInucleus  mitochondrion  mitochondrion  electron carrier activity  protein disulfide oxidoreductase activity  hemopoiesis  cell redox homeostasis  metal ion binding  2 iron, 2 sulfur cluster binding  oxidation-reduction process  
NDEx NetworkGLRX5
Atlas of Cancer Signalling NetworkGLRX5
Wikipedia pathwaysGLRX5
Orthology - Evolution
OrthoDB51218
Phylogenetic Trees/Animal Genes : TreeFamGLRX5
HOVERGENQ86SX6
HOGENOMQ86SX6
Homologs : HomoloGeneGLRX5
Homology/Alignments : Family Browser (UCSC)GLRX5
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGLRX5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GLRX5
dbVarGLRX5
ClinVarGLRX5
1000_GenomesGLRX5 
Exome Variant ServerGLRX5
ExAC (Exome Aggregation Consortium)GLRX5 (select the gene name)
Genetic variants : HAPMAP51218
Genomic Variants (DGV)GLRX5 [DGVbeta]
DECIPHER (Syndromes)14:96001323-96011055  
CONAN: Copy Number AnalysisGLRX5 
Mutations
ICGC Data PortalGLRX5 
TCGA Data PortalGLRX5 
Broad Tumor PortalGLRX5
OASIS PortalGLRX5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGLRX5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGLRX5
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch GLRX5
DgiDB (Drug Gene Interaction Database)GLRX5
DoCM (Curated mutations)GLRX5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GLRX5 (select a term)
intoGenGLRX5
Cancer3DGLRX5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM205950    609588   
Orphanet19805    22844   
MedgenGLRX5
Genetic Testing Registry GLRX5
NextProtQ86SX6 [Medical]
TSGene51218
GENETestsGLRX5
Huge Navigator GLRX5 [HugePedia]
snp3D : Map Gene to Disease51218
BioCentury BCIQGLRX5
ClinGenGLRX5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51218
Chemical/Pharm GKB GenePA134992547
Clinical trialGLRX5
Miscellaneous
canSAR (ICR)GLRX5 (select the gene name)
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGLRX5
EVEXGLRX5
GoPubMedGLRX5
iHOPGLRX5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:06:14 CET 2017

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