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GLUD2 (glutamate dehydrogenase 2)

Identity

Alias_namesGLUDP1
glutamate dehydrogenase pseudogene 1
Other aliasGDH2
HGNC (Hugo) GLUD2
LocusID (NCBI) 2747
Atlas_Id 63838
Location Xq24  [Link to chromosome band Xq24]
Location_base_pair Starts at 121047608 and ends at 121049942 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GLUD2   4336
Cards
Entrez_Gene (NCBI)GLUD2  2747  glutamate dehydrogenase 2
AliasesGDH2; GLUDP1
GeneCards (Weizmann)GLUD2
Ensembl hg19 (Hinxton)ENSG00000182890 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000182890 [Gene_View]  chrX:121047608-121049942 [Contig_View]  GLUD2 [Vega]
ICGC DataPortalENSG00000182890
TCGA cBioPortalGLUD2
AceView (NCBI)GLUD2
Genatlas (Paris)GLUD2
WikiGenes2747
SOURCE (Princeton)GLUD2
Genetics Home Reference (NIH)GLUD2
Genomic and cartography
GoldenPath hg38 (UCSC)GLUD2  -     chrX:121047608-121049942 +  Xq24   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GLUD2  -     Xq24   [Description]    (hg19-Feb_2009)
EnsemblGLUD2 - Xq24 [CytoView hg19]  GLUD2 - Xq24 [CytoView hg38]
Mapping of homologs : NCBIGLUD2 [Mapview hg19]  GLUD2 [Mapview hg38]
OMIM168600   300144   
Gene and transcription
Genbank (Entrez)AK313356 BC005111 BC050732 HM005554
RefSeq transcript (Entrez)NM_012084
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GLUD2
Cluster EST : UnigeneHs.368538 [ NCBI ]
CGAP (NCI)Hs.368538
Alternative Splicing GalleryENSG00000182890
Gene ExpressionGLUD2 [ NCBI-GEO ]   GLUD2 [ EBI - ARRAY_EXPRESS ]   GLUD2 [ SEEK ]   GLUD2 [ MEM ]
Gene Expression Viewer (FireBrowse)GLUD2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2747
GTEX Portal (Tissue expression)GLUD2
Protein : pattern, domain, 3D structure
UniProt/SwissProtP49448   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP49448  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP49448
Splice isoforms : SwissVarP49448
Catalytic activity : Enzyme1.4.1.3 [ Enzyme-Expasy ]   1.4.1.31.4.1.3 [ IntEnz-EBI ]   1.4.1.3 [ BRENDA ]   1.4.1.3 [ KEGG ]   
PhosPhoSitePlusP49448
Domaine pattern : Prosite (Expaxy)GLFV_DEHYDROGENASE (PS00074)   
Domains : Interpro (EBI)Glu/Leu/Phe/Val_DH    Glu/Leu/Phe/Val_DH_AS    Glu/Leu/Phe/Val_DH_C    Glu/Leu/Phe/Val_DH_dimer_dom    NAD(P)-bd_dom    NAD_bind_Glu_DH   
Domain families : Pfam (Sanger)ELFV_dehydrog (PF00208)    ELFV_dehydrog_N (PF02812)   
Domain families : Pfam (NCBI)pfam00208    pfam02812   
Domain families : Smart (EMBL)ELFV_dehydrog (SM00839)  
Conserved Domain (NCBI)GLUD2
DMDM Disease mutations2747
Blocks (Seattle)GLUD2
SuperfamilyP49448
Human Protein AtlasENSG00000182890
Peptide AtlasP49448
HPRD02143
IPIIPI00027146   
Protein Interaction databases
DIP (DOE-UCLA)P49448
IntAct (EBI)P49448
FunCoupENSG00000182890
BioGRIDGLUD2
STRING (EMBL)GLUD2
ZODIACGLUD2
Ontologies - Pathways
QuickGOP49448
Ontology : AmiGOglutamate dehydrogenase (NAD+) activity  glutamate dehydrogenase [NAD(P)+] activity  GTP binding  cytoplasm  mitochondrion  glutamate metabolic process  glutamate biosynthetic process  glutamate catabolic process  ADP binding  oxidation-reduction process  leucine binding  
Ontology : EGO-EBIglutamate dehydrogenase (NAD+) activity  glutamate dehydrogenase [NAD(P)+] activity  GTP binding  cytoplasm  mitochondrion  glutamate metabolic process  glutamate biosynthetic process  glutamate catabolic process  ADP binding  oxidation-reduction process  leucine binding  
Pathways : KEGGAlanine, aspartate and glutamate metabolism    Arginine and proline metabolism    D-Glutamine and D-glutamate metabolism    Nitrogen metabolism    Proximal tubule bicarbonate reclamation   
NDEx NetworkGLUD2
Atlas of Cancer Signalling NetworkGLUD2
Wikipedia pathwaysGLUD2
Orthology - Evolution
OrthoDB2747
GeneTree (enSembl)ENSG00000182890
Phylogenetic Trees/Animal Genes : TreeFamGLUD2
HOVERGENP49448
HOGENOMP49448
Homologs : HomoloGeneGLUD2
Homology/Alignments : Family Browser (UCSC)GLUD2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGLUD2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GLUD2
dbVarGLUD2
ClinVarGLUD2
1000_GenomesGLUD2 
Exome Variant ServerGLUD2
ExAC (Exome Aggregation Consortium)GLUD2 (select the gene name)
Genetic variants : HAPMAP2747
Genomic Variants (DGV)GLUD2 [DGVbeta]
DECIPHERGLUD2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGLUD2 
Mutations
ICGC Data PortalGLUD2 
TCGA Data PortalGLUD2 
Broad Tumor PortalGLUD2
OASIS PortalGLUD2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGLUD2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGLUD2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
BioMutasearch GLUD2
DgiDB (Drug Gene Interaction Database)GLUD2
DoCM (Curated mutations)GLUD2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GLUD2 (select a term)
intoGenGLUD2
Cancer3DGLUD2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM168600    300144   
Orphanet
MedgenGLUD2
Genetic Testing Registry GLUD2
NextProtP49448 [Medical]
TSGene2747
GENETestsGLUD2
Target ValidationGLUD2
Huge Navigator GLUD2 [HugePedia]
snp3D : Map Gene to Disease2747
BioCentury BCIQGLUD2
ClinGenGLUD2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2747
Chemical/Pharm GKB GenePA28738
Clinical trialGLUD2
Miscellaneous
canSAR (ICR)GLUD2 (select the gene name)
Probes
Litterature
PubMed49 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGLUD2
EVEXGLUD2
GoPubMedGLUD2
iHOPGLUD2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 15:50:47 CEST 2017

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