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GLYCTK (glycerate kinase)

Identity

Alias_symbol (synonym)HBEBP4
HBEBP2
Other aliasHBeAgBP4A
HGNC (Hugo) GLYCTK
LocusID (NCBI) 132158
Atlas_Id 63843
Location 3p21.2  [Link to chromosome band 3p21]
Location_base_pair Starts at 52287820 and ends at 52293005 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
GLYCTK (3p21.1) / ALAS1 (3p21.2)GLYCTK (3p21.1) / DNAH1 (3p21.1)GLYCTK (3p21.1) / PSG3 (19q13.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GLYCTK   24247
Cards
Entrez_Gene (NCBI)GLYCTK  132158  glycerate kinase
AliasesHBEBP2; HBEBP4; HBeAgBP4A
GeneCards (Weizmann)GLYCTK
Ensembl hg19 (Hinxton)ENSG00000168237 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000168237 [Gene_View]  chr3:52287820-52293005 [Contig_View]  GLYCTK [Vega]
ICGC DataPortalENSG00000168237
TCGA cBioPortalGLYCTK
AceView (NCBI)GLYCTK
Genatlas (Paris)GLYCTK
WikiGenes132158
SOURCE (Princeton)GLYCTK
Genetics Home Reference (NIH)GLYCTK
Genomic and cartography
GoldenPath hg38 (UCSC)GLYCTK  -     chr3:52287820-52293005 +  3p21.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GLYCTK  -     3p21.2   [Description]    (hg19-Feb_2009)
EnsemblGLYCTK - 3p21.2 [CytoView hg19]  GLYCTK - 3p21.2 [CytoView hg38]
Mapping of homologs : NCBIGLYCTK [Mapview hg19]  GLYCTK [Mapview hg38]
OMIM220120   610516   
Gene and transcription
Genbank (Entrez)AA100208 AF448855 AF529373 AI380271 AK074215
RefSeq transcript (Entrez)NM_001144951 NM_145262
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GLYCTK
Cluster EST : UnigeneHs.415312 [ NCBI ]
CGAP (NCI)Hs.415312
Alternative Splicing GalleryENSG00000168237
Gene ExpressionGLYCTK [ NCBI-GEO ]   GLYCTK [ EBI - ARRAY_EXPRESS ]   GLYCTK [ SEEK ]   GLYCTK [ MEM ]
Gene Expression Viewer (FireBrowse)GLYCTK [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)132158
GTEX Portal (Tissue expression)GLYCTK
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IVS8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IVS8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IVS8
Splice isoforms : SwissVarQ8IVS8
PhosPhoSitePlusQ8IVS8
Domains : Interpro (EBI)MOFRL    MOFRL_assoc_dom   
Domain families : Pfam (Sanger)DUF4147 (PF13660)    MOFRL (PF05161)   
Domain families : Pfam (NCBI)pfam13660    pfam05161   
Conserved Domain (NCBI)GLYCTK
DMDM Disease mutations132158
Blocks (Seattle)GLYCTK
SuperfamilyQ8IVS8
Human Protein AtlasENSG00000168237
Peptide AtlasQ8IVS8
HPRD13586
IPIIPI00217117   IPI00385408   IPI00332462   IPI00735631   IPI00845254   IPI00384753   IPI00385106   IPI00946397   IPI00845451   
Protein Interaction databases
DIP (DOE-UCLA)Q8IVS8
IntAct (EBI)Q8IVS8
FunCoupENSG00000168237
BioGRIDGLYCTK
STRING (EMBL)GLYCTK
ZODIACGLYCTK
Ontologies - Pathways
QuickGOQ8IVS8
Ontology : AmiGOprotein binding  ATP binding  cytoplasm  mitochondrion  Golgi apparatus  cytosol  cytosol  protein phosphorylation  glycerate kinase activity  glycerate kinase activity  fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate  
Ontology : EGO-EBIprotein binding  ATP binding  cytoplasm  mitochondrion  Golgi apparatus  cytosol  cytosol  protein phosphorylation  glycerate kinase activity  glycerate kinase activity  fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate  
Pathways : KEGGGlycine, serine and threonine metabolism    Glycerolipid metabolism    Glyoxylate and dicarboxylate metabolism   
NDEx NetworkGLYCTK
Atlas of Cancer Signalling NetworkGLYCTK
Wikipedia pathwaysGLYCTK
Orthology - Evolution
OrthoDB132158
GeneTree (enSembl)ENSG00000168237
Phylogenetic Trees/Animal Genes : TreeFamGLYCTK
HOVERGENQ8IVS8
HOGENOMQ8IVS8
Homologs : HomoloGeneGLYCTK
Homology/Alignments : Family Browser (UCSC)GLYCTK
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGLYCTK [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GLYCTK
dbVarGLYCTK
ClinVarGLYCTK
1000_GenomesGLYCTK 
Exome Variant ServerGLYCTK
ExAC (Exome Aggregation Consortium)GLYCTK (select the gene name)
Genetic variants : HAPMAP132158
Genomic Variants (DGV)GLYCTK [DGVbeta]
DECIPHERGLYCTK [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGLYCTK 
Mutations
ICGC Data PortalGLYCTK 
TCGA Data PortalGLYCTK 
Broad Tumor PortalGLYCTK
OASIS PortalGLYCTK [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGLYCTK  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGLYCTK
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch GLYCTK
DgiDB (Drug Gene Interaction Database)GLYCTK
DoCM (Curated mutations)GLYCTK (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GLYCTK (select a term)
intoGenGLYCTK
Cancer3DGLYCTK(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM220120    610516   
Orphanet3360   
MedgenGLYCTK
Genetic Testing Registry GLYCTK
NextProtQ8IVS8 [Medical]
TSGene132158
GENETestsGLYCTK
Target ValidationGLYCTK
Huge Navigator GLYCTK [HugePedia]
snp3D : Map Gene to Disease132158
BioCentury BCIQGLYCTK
ClinGenGLYCTK
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD132158
Chemical/Pharm GKB GenePA162389865
Clinical trialGLYCTK
Miscellaneous
canSAR (ICR)GLYCTK (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGLYCTK
EVEXGLYCTK
GoPubMedGLYCTK
iHOPGLYCTK
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:09:30 CEST 2017

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