GMIP (GEM interacting protein)

2014-11-01  

Identity

HGNC
LOCATION
19p13.11
LOCUSID
ALIAS
ARHGAP46
FUSION GENES

Other Information

Locus ID:

NCBI: 51291
MIM: 609694
HGNC: 24852
Ensembl: ENSG00000089639

Variants:

dbSNP: 51291
ClinVar: 51291
TCGA: ENSG00000089639
COSMIC: GMIP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000089639ENST00000203556Q9P107
ENSG00000089639ENST00000203556A0A024R7N1
ENSG00000089639ENST00000587205K7EQR5
ENSG00000089639ENST00000587238Q9P107
ENSG00000089639ENST00000588171K7ELE8
ENSG00000089639ENST00000591047K7ELE8
ENSG00000089639ENST00000593186K7EJC2

Expression (GTEx)

0
50
100
150
200

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by Rho GTPasesREACTOMER-HSA-194315
Rho GTPase cycleREACTOMER-HSA-194840

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203517142011Poor replication of candidate genes for major depressive disorder using genome-wide association data.92
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
224385812012Vesicular trafficking through cortical actin during exocytosis is regulated by the Rab27a effector JFC1/Slp1 and the RhoA-GTPase-activating protein Gem-interacting protein.36
120933602002A novel Rho GTPase-activating-protein interacts with Gem, a member of the Ras superfamily of GTPases.22
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.11
160861842005The Gem interacting protein (GMIP) gene is associated with major depressive disorder.5
160861842005The Gem interacting protein (GMIP) gene is associated with major depressive disorder.5
251738852014Gem GTPase acts upstream Gmip/RhoA to regulate cortical actin remodeling and spindle positioning during early mitosis.4

Citation

Dessen P

GMIP (GEM interacting protein)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/63854/gmip