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GMNN (geminin, DNA replication inhibitor)

Identity

Alias_symbol (synonym)Gem
Other aliasMGORS6
HGNC (Hugo) GMNN
LocusID (NCBI) 51053
Atlas_Id 43271
Location 6p22.3  [Link to chromosome band 6p22]
Location_base_pair Starts at 24774931 and ends at 24786097 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
GMNN (6p22.3) / GMNN (6p22.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GMNN   17493
Cards
Entrez_Gene (NCBI)GMNN  51053  geminin, DNA replication inhibitor
AliasesGem; MGORS6
GeneCards (Weizmann)GMNN
Ensembl hg19 (Hinxton)ENSG00000112312 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000112312 [Gene_View]  ENSG00000112312 [Sequence]  chr6:24774931-24786097 [Contig_View]  GMNN [Vega]
ICGC DataPortalENSG00000112312
TCGA cBioPortalGMNN
AceView (NCBI)GMNN
Genatlas (Paris)GMNN
WikiGenes51053
SOURCE (Princeton)GMNN
Genetics Home Reference (NIH)GMNN
Genomic and cartography
GoldenPath hg38 (UCSC)GMNN  -     chr6:24774931-24786097 +  6p22.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GMNN  -     6p22.3   [Description]    (hg19-Feb_2009)
EnsemblGMNN - 6p22.3 [CytoView hg19]  GMNN - 6p22.3 [CytoView hg38]
Mapping of homologs : NCBIGMNN [Mapview hg19]  GMNN [Mapview hg38]
OMIM602842   616835   
Gene and transcription
Genbank (Entrez)AF067855 AK021685 AK222992 AK315743 AL558330
RefSeq transcript (Entrez)NM_001251989 NM_001251990 NM_001251991 NM_015895
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GMNN
Cluster EST : UnigeneHs.234896 [ NCBI ]
CGAP (NCI)Hs.234896
Alternative Splicing GalleryENSG00000112312
Gene ExpressionGMNN [ NCBI-GEO ]   GMNN [ EBI - ARRAY_EXPRESS ]   GMNN [ SEEK ]   GMNN [ MEM ]
Gene Expression Viewer (FireBrowse)GMNN [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51053
GTEX Portal (Tissue expression)GMNN
Human Protein AtlasENSG00000112312-GMNN [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75496   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75496  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75496
Splice isoforms : SwissVarO75496
PhosPhoSitePlusO75496
Domains : Interpro (EBI)Geminin    Geminin/Multicilin   
Domain families : Pfam (Sanger)Geminin (PF07412)   
Domain families : Pfam (NCBI)pfam07412   
Conserved Domain (NCBI)GMNN
DMDM Disease mutations51053
Blocks (Seattle)GMNN
PDB (SRS)1T6F    1UII    2LP0    2WVR    4BRY   
PDB (PDBSum)1T6F    1UII    2LP0    2WVR    4BRY   
PDB (IMB)1T6F    1UII    2LP0    2WVR    4BRY   
PDB (RSDB)1T6F    1UII    2LP0    2WVR    4BRY   
Structural Biology KnowledgeBase1T6F    1UII    2LP0    2WVR    4BRY   
SCOP (Structural Classification of Proteins)1T6F    1UII    2LP0    2WVR    4BRY   
CATH (Classification of proteins structures)1T6F    1UII    2LP0    2WVR    4BRY   
SuperfamilyO75496
Human Protein Atlas [tissue]ENSG00000112312-GMNN [tissue]
Peptide AtlasO75496
HPRD06783
IPIIPI00026309   IPI00945454   IPI00945191   IPI00945040   
Protein Interaction databases
DIP (DOE-UCLA)O75496
IntAct (EBI)O75496
FunCoupENSG00000112312
BioGRIDGMNN
STRING (EMBL)GMNN
ZODIACGMNN
Ontologies - Pathways
QuickGOO75496
Ontology : AmiGOG1/S transition of mitotic cell cycle  chromatin binding  transcription corepressor activity  protein binding  nucleus  nucleoplasm  cytoplasm  cytosol  cytosol  regulation of DNA replication  negative regulation of DNA replication  animal organ morphogenesis  positive regulation of chromatin binding  histone deacetylase binding  negative regulation of cell cycle  negative regulation of transcription, DNA-templated  repressing transcription factor binding  DNA replication preinitiation complex assembly  negative regulation of DNA-dependent DNA replication  
Ontology : EGO-EBIG1/S transition of mitotic cell cycle  chromatin binding  transcription corepressor activity  protein binding  nucleus  nucleoplasm  cytoplasm  cytosol  cytosol  regulation of DNA replication  negative regulation of DNA replication  animal organ morphogenesis  positive regulation of chromatin binding  histone deacetylase binding  negative regulation of cell cycle  negative regulation of transcription, DNA-templated  repressing transcription factor binding  DNA replication preinitiation complex assembly  negative regulation of DNA-dependent DNA replication  
NDEx NetworkGMNN
Atlas of Cancer Signalling NetworkGMNN
Wikipedia pathwaysGMNN
Orthology - Evolution
OrthoDB51053
GeneTree (enSembl)ENSG00000112312
Phylogenetic Trees/Animal Genes : TreeFamGMNN
HOVERGENO75496
HOGENOMO75496
Homologs : HomoloGeneGMNN
Homology/Alignments : Family Browser (UCSC)GMNN
Gene fusions - Rearrangements
Fusion : QuiverGMNN
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGMNN [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GMNN
dbVarGMNN
ClinVarGMNN
1000_GenomesGMNN 
Exome Variant ServerGMNN
ExAC (Exome Aggregation Consortium)ENSG00000112312
GNOMAD BrowserENSG00000112312
Varsome BrowserGMNN
Genetic variants : HAPMAP51053
Genomic Variants (DGV)GMNN [DGVbeta]
DECIPHERGMNN [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGMNN 
Mutations
ICGC Data PortalGMNN 
TCGA Data PortalGMNN 
Broad Tumor PortalGMNN
OASIS PortalGMNN [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGMNN  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGMNN
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GMNN
DgiDB (Drug Gene Interaction Database)GMNN
DoCM (Curated mutations)GMNN (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GMNN (select a term)
intoGenGMNN
Cancer3DGMNN(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602842    616835   
Orphanet2357   
DisGeNETGMNN
MedgenGMNN
Genetic Testing Registry GMNN
NextProtO75496 [Medical]
TSGene51053
GENETestsGMNN
Target ValidationGMNN
Huge Navigator GMNN [HugePedia]
snp3D : Map Gene to Disease51053
BioCentury BCIQGMNN
ClinGenGMNN
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51053
Chemical/Pharm GKB GenePA38455
Clinical trialGMNN
Miscellaneous
canSAR (ICR)GMNN (select the gene name)
Probes
Litterature
PubMed107 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGMNN
EVEXGMNN
GoPubMedGMNN
iHOPGMNN
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 11:08:46 CET 2018

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