GMPR (guanosine monophosphate reductase)

2014-08-01  

Identity

HGNC
LOCATION
6p22.3
LOCUSID
ALIAS
GMPR
FUSION GENES

Other Information

Locus ID:

NCBI: 2766
MIM: 139265
HGNC: 4376
Ensembl: ENSG00000137198

Variants:

dbSNP: 2766
ClinVar: 2766
TCGA: ENSG00000137198
COSMIC: GMPR

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000137198ENST00000259727P36959

Expression (GTEx)

0
50
100
150
200
250
300

Pathways

PathwaySourceExternal ID
Purine metabolismKEGGko00230
Purine metabolismKEGGhsa00230
MetabolismREACTOMER-HSA-1430728
Metabolism of nucleotidesREACTOMER-HSA-15869
Purine metabolismREACTOMER-HSA-73847
Purine salvageREACTOMER-HSA-74217

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
208646722010Genetic variants influencing circulating lipid levels and risk of coronary artery disease.180
199362222009Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.151
241398042013A purine nucleotide biosynthesis enzyme guanosine monophosphate reductase is a suppressor of melanoma invasion.16

Citation

Dessen P

GMPR (guanosine monophosphate reductase)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54334/gmpr