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GMPR2 (guanosine monophosphate reductase 2)

Identity

Other aliasGMPR 2
HGNC (Hugo) GMPR2
LocusID (NCBI) 51292
Atlas_Id 45715
Location 14q12  [Link to chromosome band 14q12]
Location_base_pair Starts at 24232422 and ends at 24239241 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
GMPR2 (14q12) / STOML2 (9p13.3)JUN (1p32.1) / GMPR2 (14q12)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GMPR2   4377
Cards
Entrez_Gene (NCBI)GMPR2  51292  guanosine monophosphate reductase 2
AliasesGMPR
GeneCards (Weizmann)GMPR2
Ensembl hg19 (Hinxton)ENSG00000100938 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000100938 [Gene_View]  chr14:24232422-24239241 [Contig_View]  GMPR2 [Vega]
ICGC DataPortalENSG00000100938
TCGA cBioPortalGMPR2
AceView (NCBI)GMPR2
Genatlas (Paris)GMPR2
WikiGenes51292
SOURCE (Princeton)GMPR2
Genetics Home Reference (NIH)GMPR2
Genomic and cartography
GoldenPath hg38 (UCSC)GMPR2  -     chr14:24232422-24239241 +  14q12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GMPR2  -     14q12   [Description]    (hg19-Feb_2009)
EnsemblGMPR2 - 14q12 [CytoView hg19]  GMPR2 - 14q12 [CytoView hg38]
Mapping of homologs : NCBIGMPR2 [Mapview hg19]  GMPR2 [Mapview hg38]
OMIM610781   
Gene and transcription
Genbank (Entrez)AB032903 AF086919 AF135159 AF419346 AK226166
RefSeq transcript (Entrez)NM_001002000 NM_001002001 NM_001002002 NM_001283021 NM_001283022 NM_001283023 NM_016576
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GMPR2
Cluster EST : UnigeneHs.368855 [ NCBI ]
CGAP (NCI)Hs.368855
Alternative Splicing GalleryENSG00000100938
Gene ExpressionGMPR2 [ NCBI-GEO ]   GMPR2 [ EBI - ARRAY_EXPRESS ]   GMPR2 [ SEEK ]   GMPR2 [ MEM ]
Gene Expression Viewer (FireBrowse)GMPR2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51292
GTEX Portal (Tissue expression)GMPR2
Human Protein AtlasENSG00000100938-GMPR2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9P2T1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9P2T1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9P2T1
Splice isoforms : SwissVarQ9P2T1
PhosPhoSitePlusQ9P2T1
Domaine pattern : Prosite (Expaxy)IMP_DH_GMP_RED (PS00487)   
Domains : Interpro (EBI)Aldolase_TIM    GMPR    IMP_DH/GMP_Rdtase_CS    IMP_DH_GMPRt   
Domain families : Pfam (Sanger)IMPDH (PF00478)   
Domain families : Pfam (NCBI)pfam00478   
Conserved Domain (NCBI)GMPR2
DMDM Disease mutations51292
Blocks (Seattle)GMPR2
PDB (SRS)2A7R    2BZN    2C6Q   
PDB (PDBSum)2A7R    2BZN    2C6Q   
PDB (IMB)2A7R    2BZN    2C6Q   
PDB (RSDB)2A7R    2BZN    2C6Q   
Structural Biology KnowledgeBase2A7R    2BZN    2C6Q   
SCOP (Structural Classification of Proteins)2A7R    2BZN    2C6Q   
CATH (Classification of proteins structures)2A7R    2BZN    2C6Q   
SuperfamilyQ9P2T1
Human Protein Atlas [tissue]ENSG00000100938-GMPR2 [tissue]
Peptide AtlasQ9P2T1
HPRD13590
IPIIPI00009844   IPI00433025   IPI00449197   IPI00385158   IPI00941706   
Protein Interaction databases
DIP (DOE-UCLA)Q9P2T1
IntAct (EBI)Q9P2T1
FunCoupENSG00000100938
BioGRIDGMPR2
STRING (EMBL)GMPR2
ZODIACGMPR2
Ontologies - Pathways
QuickGOQ9P2T1
Ontology : AmiGOGMP reductase activity  GMP reductase activity  cytosol  purine nucleobase metabolic process  purine-containing compound salvage  GMP metabolic process  metal ion binding  oxidation-reduction process  GMP reductase complex  
Ontology : EGO-EBIGMP reductase activity  GMP reductase activity  cytosol  purine nucleobase metabolic process  purine-containing compound salvage  GMP metabolic process  metal ion binding  oxidation-reduction process  GMP reductase complex  
Pathways : KEGGPurine metabolism   
NDEx NetworkGMPR2
Atlas of Cancer Signalling NetworkGMPR2
Wikipedia pathwaysGMPR2
Orthology - Evolution
OrthoDB51292
GeneTree (enSembl)ENSG00000100938
Phylogenetic Trees/Animal Genes : TreeFamGMPR2
HOVERGENQ9P2T1
HOGENOMQ9P2T1
Homologs : HomoloGeneGMPR2
Homology/Alignments : Family Browser (UCSC)GMPR2
Gene fusions - Rearrangements
Tumor Fusion PortalGMPR2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGMPR2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GMPR2
dbVarGMPR2
ClinVarGMPR2
1000_GenomesGMPR2 
Exome Variant ServerGMPR2
ExAC (Exome Aggregation Consortium)ENSG00000100938
GNOMAD BrowserENSG00000100938
Genetic variants : HAPMAP51292
Genomic Variants (DGV)GMPR2 [DGVbeta]
DECIPHERGMPR2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGMPR2 
Mutations
ICGC Data PortalGMPR2 
TCGA Data PortalGMPR2 
Broad Tumor PortalGMPR2
OASIS PortalGMPR2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGMPR2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGMPR2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GMPR2
DgiDB (Drug Gene Interaction Database)GMPR2
DoCM (Curated mutations)GMPR2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GMPR2 (select a term)
intoGenGMPR2
Cancer3DGMPR2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610781   
Orphanet
DisGeNETGMPR2
MedgenGMPR2
Genetic Testing Registry GMPR2
NextProtQ9P2T1 [Medical]
TSGene51292
GENETestsGMPR2
Target ValidationGMPR2
Huge Navigator GMPR2 [HugePedia]
snp3D : Map Gene to Disease51292
BioCentury BCIQGMPR2
ClinGenGMPR2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51292
Chemical/Pharm GKB GenePA28762
Clinical trialGMPR2
Miscellaneous
canSAR (ICR)GMPR2 (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGMPR2
EVEXGMPR2
GoPubMedGMPR2
iHOPGMPR2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:14:48 CET 2017

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