Atlas of Genetics and Cytogenetics in Oncology and Haematology

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GNA15 (G protein subunit alpha 15)

Identity

Alias (NCBI)GNA16
HGNC (Hugo) GNA15
HGNC Alias symbGNA16
HGNC Previous nameguanine nucleotide binding protein (G protein), alpha 15 (Gq class)
LocusID (NCBI) 2769
Atlas_Id 43275
Location 19p13.3  [Link to chromosome band 19p13]
Location_base_pair Starts at 3136033 and ends at 3163749 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
GNA15 (19p13.3) / FKBP15 (9q32)KMT2A (11q23.3) / GNA15 (19p13.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)GNA15   4383
Cards
Entrez_Gene (NCBI)GNA15    G protein subunit alpha 15
AliasesGNA16
GeneCards (Weizmann)GNA15
Ensembl hg19 (Hinxton)ENSG00000060558 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000060558 [Gene_View]  ENSG00000060558 [Sequence]  chr19:3136033-3163749 [Contig_View]  GNA15 [Vega]
ICGC DataPortalENSG00000060558
TCGA cBioPortalGNA15
AceView (NCBI)GNA15
Genatlas (Paris)GNA15
SOURCE (Princeton)GNA15
Genetics Home Reference (NIH)GNA15
Genomic and cartography
GoldenPath hg38 (UCSC)GNA15  -     chr19:3136033-3163749 +  19p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GNA15  -     19p13.3   [Description]    (hg19-Feb_2009)
GoldenPathGNA15 - 19p13.3 [CytoView hg19]  GNA15 - 19p13.3 [CytoView hg38]
ImmunoBaseENSG00000060558
genome Data Viewer NCBIGNA15 [Mapview hg19]  
OMIM139314   
Gene and transcription
Genbank (Entrez)AF493904 AK291329 AK300481 BC013585 BG178215
RefSeq transcript (Entrez)NM_002068
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GNA15
Alternative Splicing GalleryENSG00000060558
Gene ExpressionGNA15 [ NCBI-GEO ]   GNA15 [ EBI - ARRAY_EXPRESS ]   GNA15 [ SEEK ]   GNA15 [ MEM ]
Gene Expression Viewer (FireBrowse)GNA15 [ Firebrowse - Broad ]
GenevisibleExpression of GNA15 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2769
GTEX Portal (Tissue expression)GNA15
Human Protein AtlasENSG00000060558-GNA15 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP30679   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP30679  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP30679
Splice isoforms : SwissVarP30679
PhosPhoSitePlusP30679
Domaine pattern : Prosite (Expaxy)G_ALPHA (PS51882)   
Domains : Interpro (EBI)Gprotein_alpha_Q    Gprotein_alpha_su    GproteinA_insert    P-loop_NTPase   
Domain families : Pfam (Sanger)G-alpha (PF00503)   
Domain families : Pfam (NCBI)pfam00503   
Domain families : Smart (EMBL)G_alpha (SM00275)  
Conserved Domain (NCBI)GNA15
Blocks (Seattle)GNA15
SuperfamilyP30679
Human Protein Atlas [tissue]ENSG00000060558-GNA15 [tissue]
Peptide AtlasP30679
HPRD00760
IPIIPI00027243   
Protein Interaction databases
DIP (DOE-UCLA)P30679
IntAct (EBI)P30679
BioGRIDGNA15
STRING (EMBL)GNA15
ZODIACGNA15
Ontologies - Pathways
QuickGOP30679
Ontology : AmiGOaction potential  G protein-coupled receptor binding  G protein-coupled receptor binding  GTPase activity  GTP binding  heterotrimeric G-protein complex  heterotrimeric G-protein complex  plasma membrane  G protein-coupled receptor signaling pathway  adenylate cyclase-modulating G protein-coupled receptor signaling pathway  activation of phospholipase C activity  phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway  platelet activation  G-protein beta/gamma-subunit complex binding  type 2A serotonin receptor binding  synapse  metal ion binding  positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway  phospholipase C-activating dopamine receptor signaling pathway  
Ontology : EGO-EBIaction potential  G protein-coupled receptor binding  G protein-coupled receptor binding  GTPase activity  GTP binding  heterotrimeric G-protein complex  heterotrimeric G-protein complex  plasma membrane  G protein-coupled receptor signaling pathway  adenylate cyclase-modulating G protein-coupled receptor signaling pathway  activation of phospholipase C activity  phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway  platelet activation  G-protein beta/gamma-subunit complex binding  type 2A serotonin receptor binding  synapse  metal ion binding  positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway  phospholipase C-activating dopamine receptor signaling pathway  
Pathways : KEGGCalcium signaling pathway    Chagas disease (American trypanosomiasis)    Amoebiasis   
NDEx NetworkGNA15
Atlas of Cancer Signalling NetworkGNA15
Wikipedia pathwaysGNA15
Orthology - Evolution
OrthoDB2769
GeneTree (enSembl)ENSG00000060558
Phylogenetic Trees/Animal Genes : TreeFamGNA15
HOGENOMP30679
Homologs : HomoloGeneGNA15
Homology/Alignments : Family Browser (UCSC)GNA15
Gene fusions - Rearrangements
Fusion : QuiverGNA15
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGNA15 [hg38]
dbVarGNA15
ClinVarGNA15
MonarchGNA15
1000_GenomesGNA15 
Exome Variant ServerGNA15
GNOMAD BrowserENSG00000060558
Varsome BrowserGNA15
Genomic Variants (DGV)GNA15 [DGVbeta]
DECIPHERGNA15 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGNA15 
Mutations
ICGC Data PortalGNA15 
TCGA Data PortalGNA15 
Broad Tumor PortalGNA15
OASIS PortalGNA15 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGNA15  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DGNA15
Mutations and Diseases : HGMDGNA15
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GNA15
DgiDB (Drug Gene Interaction Database)GNA15
DoCM (Curated mutations)GNA15 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GNA15 (select a term)
intoGenGNA15
Cancer3DGNA15(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM139314   
Orphanet
DisGeNETGNA15
MedgenGNA15
Genetic Testing Registry GNA15
NextProtP30679 [Medical]
GENETestsGNA15
Target ValidationGNA15
Huge Navigator GNA15 [HugePedia]
ClinGenGNA15
Clinical trials, drugs, therapy
MyCancerGenomeGNA15
Protein Interactions : CTD
Pharm GKB GenePA28768
Pharm GKB PathwaysPA154444041   
PharosP30679
Clinical trialGNA15
Miscellaneous
canSAR (ICR)GNA15 (select the gene name)
HarmonizomeGNA15
DataMed IndexGNA15
Probes
Litterature
PubMed47 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXGNA15
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri Jan 1 18:17:16 CET 2021
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