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GNA15 (G protein subunit alpha 15)

Identity

Alias_namesguanine nucleotide binding protein (G protein)
Alias_symbol (synonym)GNA16
Other alias
HGNC (Hugo) GNA15
LocusID (NCBI) 2769
Atlas_Id 43275
Location 19p13.3  [Link to chromosome band 19p13]
Location_base_pair Starts at 3136032 and ends at 3163769 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)		GNA15 (19p13.3) / FKBP15 (9q32)KMT2A (11q23.3) / GNA15 (19p13.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)GNA15   4383
Cards
Entrez_Gene (NCBI)GNA15  2769  G protein subunit alpha 15
AliasesGNA16
GeneCards (Weizmann)GNA15
Ensembl hg19 (Hinxton)ENSG00000060558 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000060558 [Gene_View]  chr19:3136032-3163769 [Contig_View]  GNA15 [Vega]
ICGC DataPortalENSG00000060558
TCGA cBioPortalGNA15
AceView (NCBI)GNA15
Genatlas (Paris)GNA15
WikiGenes2769
SOURCE (Princeton)GNA15
Genetics Home Reference (NIH)GNA15
Genomic and cartography
GoldenPath hg38 (UCSC)GNA15  -     chr19:3136032-3163769 +  19p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GNA15  -     19p13.3   [Description]    (hg19-Feb_2009)
EnsemblGNA15 - 19p13.3 [CytoView hg19]  GNA15 - 19p13.3 [CytoView hg38]
Mapping of homologs : NCBIGNA15 [Mapview hg19]  GNA15 [Mapview hg38]
OMIM139314   
Gene and transcription
Genbank (Entrez)AF493904 AK291329 AK300481 BC013585 BG178215
RefSeq transcript (Entrez)NM_002068
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GNA15
Cluster EST : UnigeneHs.73797 [ NCBI ]
CGAP (NCI)Hs.73797
Alternative Splicing GalleryENSG00000060558
Gene ExpressionGNA15 [ NCBI-GEO ]   GNA15 [ EBI - ARRAY_EXPRESS ]   GNA15 [ SEEK ]   GNA15 [ MEM ]
Gene Expression Viewer (FireBrowse)GNA15 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2769
GTEX Portal (Tissue expression)GNA15
Protein : pattern, domain, 3D structure
UniProt/SwissProtP30679   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP30679  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP30679
Splice isoforms : SwissVarP30679
PhosPhoSitePlusP30679
Domains : Interpro (EBI)Gprotein_alpha_Q    Gprotein_alpha_su    GproteinA_insert    P-loop_NTPase   
Domain families : Pfam (Sanger)G-alpha (PF00503)   
Domain families : Pfam (NCBI)pfam00503   
Domain families : Smart (EMBL)G_alpha (SM00275)  
Conserved Domain (NCBI)GNA15
DMDM Disease mutations2769
Blocks (Seattle)GNA15
SuperfamilyP30679
Human Protein AtlasENSG00000060558
Peptide AtlasP30679
HPRD00760
IPIIPI00027243   
Protein Interaction databases
DIP (DOE-UCLA)P30679
IntAct (EBI)P30679
FunCoupENSG00000060558
BioGRIDGNA15
STRING (EMBL)GNA15
ZODIACGNA15
Ontologies - Pathways
QuickGOP30679
Ontology : AmiGOG-protein coupled receptor binding  GTPase activity  GTPase activity  signal transducer activity  GTP binding  heterotrimeric G-protein complex  heterotrimeric G-protein complex  plasma membrane  adenylate cyclase-modulating G-protein coupled receptor signaling pathway  activation of phospholipase C activity  positive regulation of cytosolic calcium ion concentration  phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway  platelet activation  G-protein beta/gamma-subunit complex binding  metal ion binding  phospholipase C-activating dopamine receptor signaling pathway  
Ontology : EGO-EBIG-protein coupled receptor binding  GTPase activity  GTPase activity  signal transducer activity  GTP binding  heterotrimeric G-protein complex  heterotrimeric G-protein complex  plasma membrane  adenylate cyclase-modulating G-protein coupled receptor signaling pathway  activation of phospholipase C activity  positive regulation of cytosolic calcium ion concentration  phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway  platelet activation  G-protein beta/gamma-subunit complex binding  metal ion binding  phospholipase C-activating dopamine receptor signaling pathway  
Pathways : BIOCARTAfMLP induced chemokine gene expression in HMC-1 cells [Genes]   
Pathways : KEGGCalcium signaling pathway    Chagas disease (American trypanosomiasis)    Amoebiasis   
NDEx NetworkGNA15
Atlas of Cancer Signalling NetworkGNA15
Wikipedia pathwaysGNA15
Orthology - Evolution
OrthoDB2769
GeneTree (enSembl)ENSG00000060558
Phylogenetic Trees/Animal Genes : TreeFamGNA15
HOVERGENP30679
HOGENOMP30679
Homologs : HomoloGeneGNA15
Homology/Alignments : Family Browser (UCSC)GNA15
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGNA15 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GNA15
dbVarGNA15
ClinVarGNA15
1000_GenomesGNA15 
Exome Variant ServerGNA15
ExAC (Exome Aggregation Consortium)GNA15 (select the gene name)
Genetic variants : HAPMAP2769
Genomic Variants (DGV)GNA15 [DGVbeta]
DECIPHERGNA15 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGNA15 
Mutations
ICGC Data PortalGNA15 
TCGA Data PortalGNA15 
Broad Tumor PortalGNA15
OASIS PortalGNA15 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGNA15  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGNA15
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GNA15
DgiDB (Drug Gene Interaction Database)GNA15
DoCM (Curated mutations)GNA15 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GNA15 (select a term)
intoGenGNA15
Cancer3DGNA15(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM139314   
Orphanet
MedgenGNA15
Genetic Testing Registry GNA15
NextProtP30679 [Medical]
TSGene2769
GENETestsGNA15
Target ValidationGNA15
Huge Navigator GNA15 [HugePedia]
snp3D : Map Gene to Disease2769
BioCentury BCIQGNA15
ClinGenGNA15
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2769
Chemical/Pharm GKB GenePA28768
Clinical trialGNA15
Miscellaneous
canSAR (ICR)GNA15 (select the gene name)
Probes
Litterature
PubMed45 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGNA15
EVEXGNA15
GoPubMedGNA15
iHOPGNA15
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:35:29 CEST 2017
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