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GNAI3 (guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3)

Identity

Other names87U6
ARCND1
HGNC (Hugo) GNAI3
LocusID (NCBI) 2773
Location 1p13.3
Location_base_pair Starts at 110091186 and ends at 110138454 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)GNAI3   4387
Cards
Entrez_Gene (NCBI)GNAI3  2773  guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
GeneCards (Weizmann)GNAI3
Ensembl (Hinxton) [Gene_View]  chr1:110091186-110138454 [Contig_View]  GNAI3 [Vega]
AceView (NCBI)GNAI3
Genatlas (Paris)GNAI3
WikiGenes2773
SOURCE (Princeton)NM_006496
Genomic and cartography
GoldenPath (UCSC)GNAI3  -  1p13.3   chr1:110091186-110138454 +  1p13.3   [Description]    (hg19-Feb_2009)
EnsemblGNAI3 - 1p13.3 [CytoView]
Mapping of homologs : NCBIGNAI3 [Mapview]
OMIM139370   602483   603483   
Gene and transcription
Genbank (Entrez)AF493907 AI684171 AK130069 AK311691 AK312252
RefSeq transcript (Entrez)NM_006496
RefSeq genomic (Entrez)AC_000133 NC_000001 NC_018912 NG_032795 NT_032977 NW_001838594 NW_004929290
Consensus coding sequences : CCDS (NCBI)GNAI3
Cluster EST : UnigeneHs.741171 [ NCBI ]
CGAP (NCI)Hs.741171
Alternative Splicing : Fast-db (Paris)GSHG0000775
Gene ExpressionGNAI3 [ NCBI-GEO ]     GNAI3 [ SEEK ]   GNAI3 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP08754 (Uniprot)
NextProtP08754  [Medical]
With graphics : InterProP08754
Splice isoforms : SwissVarP08754 (Swissvar)
Domains : Interpro (EBI)Gprotein_alpha_I    Gprotein_alpha_su    GproteinA_insert    P-loop_NTPase   
Related proteins : CluSTrP08754
Domain families : Pfam (Sanger)G-alpha (PF00503)   
Domain families : Pfam (NCBI)pfam00503   
Domain families : Smart (EMBL)G_alpha (SM00275)  
DMDM Disease mutations2773
Blocks (Seattle)P08754
PDB (SRS)2IHB    2ODE    2V4Z    4G5O    4G5R    4G5S   
PDB (PDBSum)2IHB    2ODE    2V4Z    4G5O    4G5R    4G5S   
PDB (IMB)2IHB    2ODE    2V4Z    4G5O    4G5R    4G5S   
PDB (RSDB)2IHB    2ODE    2V4Z    4G5O    4G5R    4G5S   
Peptide AtlasP08754
HPRD00765
IPIIPI00220578   
Protein Interaction databases
DIP (DOE-UCLA)P08754
IntAct (EBI)P08754
BioGRIDGNAI3
InParanoidP08754
Interologous Interaction database P08754
IntegromeDBGNAI3
STRING (EMBL)GNAI3
Ontologies - Pathways
Ontology : AmiGOGTPase activity  signal transducer activity  GTP binding  cytoplasm  lysosomal membrane  Golgi apparatus  centrosome  heterotrimeric G-protein complex  plasma membrane  plasma membrane  transport  vesicle fusion  cell cycle  adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway  negative regulation of adenylate cyclase activity  synaptic transmission  blood coagulation  platelet activation  midbody  extrinsic to cytoplasmic side of plasma membrane  G-protein beta/gamma-subunit complex binding  G-protein coupled serotonin receptor binding  zymogen granule  membrane raft  metal ion binding  cell division  
Ontology : EGO-EBIGTPase activity  signal transducer activity  GTP binding  cytoplasm  lysosomal membrane  Golgi apparatus  centrosome  heterotrimeric G-protein complex  plasma membrane  plasma membrane  transport  vesicle fusion  cell cycle  adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway  negative regulation of adenylate cyclase activity  synaptic transmission  blood coagulation  platelet activation  midbody  extrinsic to cytoplasmic side of plasma membrane  G-protein beta/gamma-subunit complex binding  G-protein coupled serotonin receptor binding  zymogen granule  membrane raft  metal ion binding  cell division  
Pathways : KEGGRap1 signaling pathway    Chemokine signaling pathway    Adrenergic signaling in cardiomyocytes    Axon guidance    Tight junction    Gap junction    Leukocyte transendothelial migration    Circadian entrainment    Retrograde endocannabinoid signaling    Glutamatergic synapse    Cholinergic synapse    Serotonergic synapse    GABAergic synapse    Dopaminergic synapse    Long-term depression    Progesterone-mediated oocyte maturation    Estrogen signaling pathway    Melanogenesis    Gastric acid secretion    Parkinson's disease    Cocaine addiction    Morphine addiction    Alcoholism    Pertussis    Chagas disease (American trypanosomiasis)    Toxoplasmosis   
REACTOMEGNAI3
Protein Interaction DatabaseGNAI3
Wikipedia pathwaysGNAI3
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)GNAI3
SNP (GeneSNP Utah)GNAI3
SNP : HGBaseGNAI3
Genetic variants : HAPMAPGNAI3
1000_GenomesGNAI3 
Somatic Mutations in Cancer : COSMICGNAI3 
CONAN: Copy Number AnalysisGNAI3 
Mutations and Diseases : HGMDGNAI3
OMIM139370    602483    603483   
GENETestsGNAI3
Disease Genetic AssociationGNAI3
Huge Navigator GNAI3 [HugePedia]  GNAI3 [HugeCancerGEM]
Genomic VariantsGNAI3  GNAI3 [DGVbeta]
Exome VariantGNAI3
dbVarGNAI3
ClinVarGNAI3
snp3D : Map Gene to Disease2773
General knowledge
Homologs : HomoloGeneGNAI3
Homology/Alignments : Family Browser (UCSC)GNAI3
Phylogenetic Trees/Animal Genes : TreeFamGNAI3
Chemical/Protein Interactions : CTD2773
Chemical/Pharm GKB GenePA173
Clinical trialGNAI3
Other databases
Probes
Litterature
PubMed103 Pubmed reference(s) in Entrez
CoreMineGNAI3
iHOPGNAI3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Apr 18 17:14:23 CEST 2014

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