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GNAI3 (G protein subunit alpha i3)

Identity

Other names87U6
ARCND1
HGNC (Hugo) GNAI3
LocusID (NCBI) 2773
Atlas_Id 43277
Location 1p13.3
Location_base_pair Starts at 110091186 and ends at 110138454 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
GNAI3 (1p13.3) / CASQ2 (1p13.1)GNAI3 (1p13.3) / GNAI3 (1p13.3)GNAI3 (1p13.3) / KIAA1324 (1p13.3)
GNAI3 (1p13.3) / SARS (1p13.3)KIF1C (17p13.2) / GNAI3 (1p13.3)LAMC1 (1q25.3) / GNAI3 (1p13.3)
WDR74 (11q12.3) / GNAI3 (1p13.3)GNAI3 1p13.3 / CASQ2 1p13.1GNAI3 1p13.3 / KIAA1324 1p13.3
GNAI3 1p13.3 / SARS 1p13.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GNAI3   4387
Cards
Entrez_Gene (NCBI)GNAI3  2773  G protein subunit alpha i3
GeneCards (Weizmann)GNAI3
Ensembl hg19 (Hinxton)ENSG00000065135 [Gene_View]  chr1:110091186-110138454 [Contig_View]  GNAI3 [Vega]
Ensembl hg38 (Hinxton)ENSG00000065135 [Gene_View]  chr1:110091186-110138454 [Contig_View]  GNAI3 [Vega]
ICGC DataPortalENSG00000065135
TCGA cBioPortalGNAI3
AceView (NCBI)GNAI3
Genatlas (Paris)GNAI3
WikiGenes2773
SOURCE (Princeton)GNAI3
Genomic and cartography
GoldenPath hg19 (UCSC)GNAI3  -     chr1:110091186-110138454 +  1p13.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)GNAI3  -     1p13.3   [Description]    (hg38-Dec_2013)
EnsemblGNAI3 - 1p13.3 [CytoView hg19]  GNAI3 - 1p13.3 [CytoView hg38]
Mapping of homologs : NCBIGNAI3 [Mapview hg19]  GNAI3 [Mapview hg38]
OMIM139370   602483   
Gene and transcription
Genbank (Entrez)AF493907 AI684171 AK130069 AK311691 AK312252
RefSeq transcript (Entrez)NM_006496
RefSeq genomic (Entrez)NC_000001 NC_018912 NG_032795 NT_032977 NW_004929290
Consensus coding sequences : CCDS (NCBI)GNAI3
Cluster EST : UnigeneHs.741171 [ NCBI ]
CGAP (NCI)Hs.741171
Alternative Splicing : Fast-db (Paris)GSHG0000775
Alternative Splicing GalleryENSG00000065135
Gene ExpressionGNAI3 [ NCBI-GEO ]   GNAI3 [ EBI - ARRAY_EXPRESS ]   GNAI3 [ SEEK ]   GNAI3 [ MEM ]
Gene Expression Viewer (FireBrowse)GNAI3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
BioGPS (Tissue expression)2773
Protein : pattern, domain, 3D structure
UniProt/SwissProtP08754 (Uniprot)
NextProtP08754  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP08754
Splice isoforms : SwissVarP08754 (Swissvar)
PhosPhoSitePlusP08754
Domains : Interpro (EBI)Gprotein_alpha_I    Gprotein_alpha_su    GproteinA_insert    P-loop_NTPase   
Domain families : Pfam (Sanger)G-alpha (PF00503)   
Domain families : Pfam (NCBI)pfam00503   
Domain families : Smart (EMBL)G_alpha (SM00275)  
DMDM Disease mutations2773
Blocks (Seattle)GNAI3
PDB (SRS)2IHB    2ODE    2V4Z    4G5O    4G5R    4G5S   
PDB (PDBSum)2IHB    2ODE    2V4Z    4G5O    4G5R    4G5S   
PDB (IMB)2IHB    2ODE    2V4Z    4G5O    4G5R    4G5S   
PDB (RSDB)2IHB    2ODE    2V4Z    4G5O    4G5R    4G5S   
Structural Biology KnowledgeBase2IHB    2ODE    2V4Z    4G5O    4G5R    4G5S   
SCOP (Structural Classification of Proteins)2IHB    2ODE    2V4Z    4G5O    4G5R    4G5S   
CATH (Classification of proteins structures)2IHB    2ODE    2V4Z    4G5O    4G5R    4G5S   
SuperfamilyP08754
Human Protein AtlasENSG00000065135
Peptide AtlasP08754
HPRD00765
IPIIPI00220578   
Protein Interaction databases
DIP (DOE-UCLA)P08754
IntAct (EBI)P08754
FunCoupENSG00000065135
BioGRIDGNAI3
STRING (EMBL)GNAI3
ZODIACGNAI3
Ontologies - Pathways
QuickGOP08754
Ontology : AmiGOG-protein coupled receptor binding  GTPase activity  GTPase activity  signal transducer activity  protein binding  GTP binding  cytoplasm  lysosomal membrane  Golgi apparatus  centrosome  heterotrimeric G-protein complex  plasma membrane  plasma membrane  protein folding  transport  vesicle fusion  cell cycle  adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway  adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway  negative regulation of adenylate cyclase activity  dopamine receptor signaling pathway  membrane  GDP binding  protein domain specific binding  midbody  G-protein beta/gamma-subunit complex binding  G-protein coupled serotonin receptor binding  GTPase activating protein binding  zymogen granule  membrane raft  GTP metabolic process  metal ion binding  cell division  extracellular exosome  
Ontology : EGO-EBIG-protein coupled receptor binding  GTPase activity  GTPase activity  signal transducer activity  protein binding  GTP binding  cytoplasm  lysosomal membrane  Golgi apparatus  centrosome  heterotrimeric G-protein complex  plasma membrane  plasma membrane  protein folding  transport  vesicle fusion  cell cycle  adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway  adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway  negative regulation of adenylate cyclase activity  dopamine receptor signaling pathway  membrane  GDP binding  protein domain specific binding  midbody  G-protein beta/gamma-subunit complex binding  G-protein coupled serotonin receptor binding  GTPase activating protein binding  zymogen granule  membrane raft  GTP metabolic process  metal ion binding  cell division  extracellular exosome  
Pathways : KEGGRap1 signaling pathway    Chemokine signaling pathway    Adrenergic signaling in cardiomyocytes    Axon guidance    Tight junction    Gap junction    Leukocyte transendothelial migration    Circadian entrainment    Retrograde endocannabinoid signaling    Glutamatergic synapse    Cholinergic synapse    Serotonergic synapse    GABAergic synapse    Dopaminergic synapse    Long-term depression    Progesterone-mediated oocyte maturation    Estrogen signaling pathway    Melanogenesis    Gastric acid secretion    Parkinson's disease    Cocaine addiction    Morphine addiction    Alcoholism    Pertussis    Chagas disease (American trypanosomiasis)    Toxoplasmosis   
NDEx Network
Atlas of Cancer Signalling NetworkGNAI3
Wikipedia pathwaysGNAI3
Orthology - Evolution
OrthoDB2773
GeneTree (enSembl)ENSG00000065135
Phylogenetic Trees/Animal Genes : TreeFamGNAI3
Homologs : HomoloGeneGNAI3
Homology/Alignments : Family Browser (UCSC)GNAI3
Gene fusions - Rearrangements
Fusion: TCGAGNAI3 1p13.3 CASQ2 1p13.1 BRCA
Fusion: TCGAGNAI3 1p13.3 KIAA1324 1p13.3 BRCA
Fusion: TCGAGNAI3 1p13.3 SARS 1p13.3 BRCA
Polymorphisms : SNP, variants
NCBI Variation ViewerGNAI3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GNAI3
dbVarGNAI3
ClinVarGNAI3
1000_GenomesGNAI3 
Exome Variant ServerGNAI3
ExAC (Exome Aggregation Consortium)GNAI3 (select the gene name)
SNP (GeneSNP Utah)GNAI3
SNP : HGBaseGNAI3
Genetic variants : HAPMAPGNAI3
Genomic Variants (DGV)GNAI3 [DGVbeta]
Mutations
ICGC Data PortalGNAI3 
TCGA Data PortalGNAI3 
Broad Tumor PortalGNAI3
OASIS PortalGNAI3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGNAI3 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GNAI3
DgiDB (Drug Gene Interaction Database)GNAI3
DoCM (Curated mutations)GNAI3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GNAI3 (select a term)
intoGenGNAI3
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)1:110091186-110138454
CONAN: Copy Number AnalysisGNAI3 
Mutations and Diseases : HGMDGNAI3
OMIM139370    602483   
MedgenGNAI3
Genetic Testing Registry GNAI3
NextProtP08754 [Medical]
TSGene2773
GENETestsGNAI3
Huge Navigator GNAI3 [HugePedia]  GNAI3 [HugeCancerGEM]
snp3D : Map Gene to Disease2773
BioCentury BCIQGNAI3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2773
Chemical/Pharm GKB GenePA173
Clinical trialGNAI3
Miscellaneous
canSAR (ICR)GNAI3 (select the gene name)
Probes
Litterature
PubMed116 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGNAI3
GoPubMedGNAI3
iHOPGNAI3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Apr 16 17:46:19 CEST 2016

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