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GNAT1 (G protein subunit alpha transducin 1)

Identity

Other namesCSNB1G
CSNBAD3
GBT1
GNATR
HGNC (Hugo) GNAT1
LocusID (NCBI) 2779
Atlas_Id 43281
Location 3p21.31  [Link to chromosome band 3p21]
Location_base_pair Starts at 50229043 and ends at 50235129 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GNAT1   4393
Cards
Entrez_Gene (NCBI)GNAT1  2779  G protein subunit alpha transducin 1
AliasesCSNB1G; CSNBAD3; GBT1; GNATR
GeneCards (Weizmann)GNAT1
Ensembl hg19 (Hinxton)ENSG00000114349 [Gene_View]  chr3:50229043-50235129 [Contig_View]  GNAT1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000114349 [Gene_View]  chr3:50229043-50235129 [Contig_View]  GNAT1 [Vega]
ICGC DataPortalENSG00000114349
TCGA cBioPortalGNAT1
AceView (NCBI)GNAT1
Genatlas (Paris)GNAT1
WikiGenes2779
SOURCE (Princeton)GNAT1
Genomic and cartography
GoldenPath hg19 (UCSC)GNAT1  -     chr3:50229043-50235129 +  3p21.31   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)GNAT1  -     3p21.31   [Description]    (hg38-Dec_2013)
EnsemblGNAT1 - 3p21.31 [CytoView hg19]  GNAT1 - 3p21.31 [CytoView hg38]
Mapping of homologs : NCBIGNAT1 [Mapview hg19]  GNAT1 [Mapview hg38]
OMIM139330   610444   616389   
Gene and transcription
Genbank (Entrez)AF493908 BC095505 BQ637667 BU727496 BU728210
RefSeq transcript (Entrez)NM_000172 NM_144499
RefSeq genomic (Entrez)NC_000003 NC_018914 NG_009831 NT_022517 NW_004929309
Consensus coding sequences : CCDS (NCBI)GNAT1
Cluster EST : UnigeneHs.517978 [ NCBI ]
CGAP (NCI)Hs.517978
Alternative Splicing GalleryENSG00000114349
Gene ExpressionGNAT1 [ NCBI-GEO ]   GNAT1 [ EBI - ARRAY_EXPRESS ]   GNAT1 [ SEEK ]   GNAT1 [ MEM ]
Gene Expression Viewer (FireBrowse)GNAT1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2779
GTEX Portal (Tissue expression)GNAT1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP11488 (Uniprot)
NextProtP11488  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP11488
Splice isoforms : SwissVarP11488 (Swissvar)
PhosPhoSitePlusP11488
Domains : Interpro (EBI)Gprotein_alpha_I    Gprotein_alpha_su    GproteinA_insert    P-loop_NTPase   
Domain families : Pfam (Sanger)G-alpha (PF00503)   
Domain families : Pfam (NCBI)pfam00503   
Domain families : Smart (EMBL)G_alpha (SM00275)  
DMDM Disease mutations2779
Blocks (Seattle)GNAT1
PDB (SRS)3RBQ   
PDB (PDBSum)3RBQ   
PDB (IMB)3RBQ   
PDB (RSDB)3RBQ   
Structural Biology KnowledgeBase3RBQ   
SCOP (Structural Classification of Proteins)3RBQ   
CATH (Classification of proteins structures)3RBQ   
SuperfamilyP11488
Human Protein AtlasENSG00000114349
Peptide AtlasP11488
HPRD08850
IPIIPI00218488   IPI00925584   
Protein Interaction databases
DIP (DOE-UCLA)P11488
IntAct (EBI)P11488
FunCoupENSG00000114349
BioGRIDGNAT1
STRING (EMBL)GNAT1
ZODIACGNAT1
Ontologies - Pathways
QuickGOP11488
Ontology : AmiGOacyl binding  detection of chemical stimulus involved in sensory perception of bitter taste  G-protein coupled receptor binding  photoreceptor outer segment  photoreceptor inner segment  GTPase activity  GTPase activity  GTPase activity  signal transducer activity  GTP binding  GTP binding  cytosol  heterotrimeric G-protein complex  plasma membrane  protein folding  signal transduction  adenylate cyclase-modulating G-protein coupled receptor signaling pathway  visual perception  phototransduction, visible light  metabolic process  cell proliferation  response to light stimulus  response to light intensity  membrane  membrane  rhodopsin mediated signaling pathway  apical plasma membrane  GDP binding  protein kinase binding  regulation of rhodopsin mediated signaling pathway  G-protein beta/gamma-subunit complex binding  photoreceptor connecting cilium  eye photoreceptor cell development  photoreceptor outer segment membrane  neuronal cell body  metal ion binding  detection of light stimulus involved in visual perception  sensory perception of umami taste  positive regulation of cyclic-nucleotide phosphodiesterase activity  negative regulation of cyclic-nucleotide phosphodiesterase activity  retina development in camera-type eye  cellular response to electrical stimulus  photoreceptor disc membrane  
Ontology : EGO-EBIacyl binding  detection of chemical stimulus involved in sensory perception of bitter taste  G-protein coupled receptor binding  photoreceptor outer segment  photoreceptor inner segment  GTPase activity  GTPase activity  GTPase activity  signal transducer activity  GTP binding  GTP binding  cytosol  heterotrimeric G-protein complex  plasma membrane  protein folding  signal transduction  adenylate cyclase-modulating G-protein coupled receptor signaling pathway  visual perception  phototransduction, visible light  metabolic process  cell proliferation  response to light stimulus  response to light intensity  membrane  membrane  rhodopsin mediated signaling pathway  apical plasma membrane  GDP binding  protein kinase binding  regulation of rhodopsin mediated signaling pathway  G-protein beta/gamma-subunit complex binding  photoreceptor connecting cilium  eye photoreceptor cell development  photoreceptor outer segment membrane  neuronal cell body  metal ion binding  detection of light stimulus involved in visual perception  sensory perception of umami taste  positive regulation of cyclic-nucleotide phosphodiesterase activity  negative regulation of cyclic-nucleotide phosphodiesterase activity  retina development in camera-type eye  cellular response to electrical stimulus  photoreceptor disc membrane  
Pathways : KEGGPhototransduction   
NDEx NetworkGNAT1
Atlas of Cancer Signalling NetworkGNAT1
Wikipedia pathwaysGNAT1
Orthology - Evolution
OrthoDB2779
GeneTree (enSembl)ENSG00000114349
Phylogenetic Trees/Animal Genes : TreeFamGNAT1
Homologs : HomoloGeneGNAT1
Homology/Alignments : Family Browser (UCSC)GNAT1
Gene fusions - Rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerGNAT1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GNAT1
dbVarGNAT1
ClinVarGNAT1
1000_GenomesGNAT1 
Exome Variant ServerGNAT1
ExAC (Exome Aggregation Consortium)GNAT1 (select the gene name)
Genetic variants : HAPMAP2779
Genomic Variants (DGV)GNAT1 [DGVbeta]
Mutations
ICGC Data PortalGNAT1 
TCGA Data PortalGNAT1 
Broad Tumor PortalGNAT1
OASIS PortalGNAT1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGNAT1 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Eye diseases - LOVD
BioMutasearch GNAT1
DgiDB (Drug Gene Interaction Database)GNAT1
DoCM (Curated mutations)GNAT1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GNAT1 (select a term)
intoGenGNAT1
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)3:50229043-50235129  ENSG00000114349
CONAN: Copy Number AnalysisGNAT1 
Mutations and Diseases : HGMDGNAT1
OMIM139330    610444    616389   
MedgenGNAT1
Genetic Testing Registry GNAT1
NextProtP11488 [Medical]
TSGene2779
GENETestsGNAT1
Huge Navigator GNAT1 [HugePedia]
snp3D : Map Gene to Disease2779
BioCentury BCIQGNAT1
ClinGenGNAT1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2779
Chemical/Pharm GKB GenePA28773
Clinical trialGNAT1
Miscellaneous
canSAR (ICR)GNAT1 (select the gene name)
Probes
Litterature
PubMed31 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGNAT1
EVEXGNAT1
GoPubMedGNAT1
iHOPGNAT1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 19 18:51:10 CEST 2016

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