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GNAT2 (G protein subunit alpha transducin 2)

Identity

Other namesACHM4
GNATC
HGNC (Hugo) GNAT2
LocusID (NCBI) 2780
Atlas_Id 43282
Location 1p13.3  [Link to chromosome band 1p13]
Location_base_pair Starts at 110145889 and ends at 110155705 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
GNAT2 (1p13.3) / GNAT2 (1p13.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GNAT2   4394
Cards
Entrez_Gene (NCBI)GNAT2  2780  G protein subunit alpha transducin 2
AliasesACHM4; GNATC
GeneCards (Weizmann)GNAT2
Ensembl hg19 (Hinxton)ENSG00000134183 [Gene_View]  chr1:110145889-110155705 [Contig_View]  GNAT2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000134183 [Gene_View]  chr1:110145889-110155705 [Contig_View]  GNAT2 [Vega]
ICGC DataPortalENSG00000134183
TCGA cBioPortalGNAT2
AceView (NCBI)GNAT2
Genatlas (Paris)GNAT2
WikiGenes2780
SOURCE (Princeton)GNAT2
Genomic and cartography
GoldenPath hg19 (UCSC)GNAT2  -     chr1:110145889-110155705 -  1p13.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)GNAT2  -     1p13.3   [Description]    (hg38-Dec_2013)
EnsemblGNAT2 - 1p13.3 [CytoView hg19]  GNAT2 - 1p13.3 [CytoView hg38]
Mapping of homologs : NCBIGNAT2 [Mapview hg19]  GNAT2 [Mapview hg38]
OMIM139340   613856   
Gene and transcription
Genbank (Entrez)AF493909 BC000233 BT009844 DQ892860 DQ896109
RefSeq transcript (Entrez)NM_005272
RefSeq genomic (Entrez)NC_000001 NC_018912 NG_009099 NT_032977 NW_004929290
Consensus coding sequences : CCDS (NCBI)GNAT2
Cluster EST : UnigeneHs.36973 [ NCBI ]
CGAP (NCI)Hs.36973
Alternative Splicing GalleryENSG00000134183
Gene ExpressionGNAT2 [ NCBI-GEO ]   GNAT2 [ EBI - ARRAY_EXPRESS ]   GNAT2 [ SEEK ]   GNAT2 [ MEM ]
Gene Expression Viewer (FireBrowse)GNAT2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2780
GTEX Portal (Tissue expression)GNAT2
Protein : pattern, domain, 3D structure
UniProt/SwissProtP19087 (Uniprot)
NextProtP19087  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP19087
Splice isoforms : SwissVarP19087 (Swissvar)
PhosPhoSitePlusP19087
Domains : Interpro (EBI)Gprotein_alpha_I    Gprotein_alpha_su    GproteinA_insert    P-loop_NTPase   
Domain families : Pfam (Sanger)G-alpha (PF00503)   
Domain families : Pfam (NCBI)pfam00503   
Domain families : Smart (EMBL)G_alpha (SM00275)  
DMDM Disease mutations2780
Blocks (Seattle)GNAT2
SuperfamilyP19087
Human Protein AtlasENSG00000134183
Peptide AtlasP19087
HPRD00762
IPIIPI00217269   
Protein Interaction databases
DIP (DOE-UCLA)P19087
IntAct (EBI)P19087
FunCoupENSG00000134183
BioGRIDGNAT2
STRING (EMBL)GNAT2
ZODIACGNAT2
Ontologies - Pathways
QuickGOP19087
Ontology : AmiGOdetection of chemical stimulus involved in sensory perception of bitter taste  G-protein coupled receptor binding  photoreceptor outer segment  photoreceptor outer segment  photoreceptor inner segment  GTPase activity  GTPase activity  signal transducer activity  GTP binding  GTP binding  cytosol  heterotrimeric G-protein complex  heterotrimeric G-protein complex  plasma membrane  protein folding  G-protein coupled receptor signaling pathway  adenylate cyclase-modulating G-protein coupled receptor signaling pathway  positive regulation of cytosolic calcium ion concentration  Wnt signaling pathway, calcium modulating pathway  visual perception  phototransduction  G-protein coupled photoreceptor activity  metabolic process  response to light intensity  G-protein beta/gamma-subunit complex binding  photoreceptor outer segment membrane  retinal cone cell development  metal ion binding  detection of light stimulus involved in visual perception  
Ontology : EGO-EBIdetection of chemical stimulus involved in sensory perception of bitter taste  G-protein coupled receptor binding  photoreceptor outer segment  photoreceptor outer segment  photoreceptor inner segment  GTPase activity  GTPase activity  signal transducer activity  GTP binding  GTP binding  cytosol  heterotrimeric G-protein complex  heterotrimeric G-protein complex  plasma membrane  protein folding  G-protein coupled receptor signaling pathway  adenylate cyclase-modulating G-protein coupled receptor signaling pathway  positive regulation of cytosolic calcium ion concentration  Wnt signaling pathway, calcium modulating pathway  visual perception  phototransduction  G-protein coupled photoreceptor activity  metabolic process  response to light intensity  G-protein beta/gamma-subunit complex binding  photoreceptor outer segment membrane  retinal cone cell development  metal ion binding  detection of light stimulus involved in visual perception  
Pathways : KEGGPhototransduction   
NDEx NetworkGNAT2
Atlas of Cancer Signalling NetworkGNAT2
Wikipedia pathwaysGNAT2
Orthology - Evolution
OrthoDB2780
GeneTree (enSembl)ENSG00000134183
Phylogenetic Trees/Animal Genes : TreeFamGNAT2
Homologs : HomoloGeneGNAT2
Homology/Alignments : Family Browser (UCSC)GNAT2
Gene fusions - Rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerGNAT2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GNAT2
dbVarGNAT2
ClinVarGNAT2
1000_GenomesGNAT2 
Exome Variant ServerGNAT2
ExAC (Exome Aggregation Consortium)GNAT2 (select the gene name)
Genetic variants : HAPMAP2780
Genomic Variants (DGV)GNAT2 [DGVbeta]
Mutations
ICGC Data PortalGNAT2 
TCGA Data PortalGNAT2 
Broad Tumor PortalGNAT2
OASIS PortalGNAT2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGNAT2 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Eye diseases - LOVD
BioMutasearch GNAT2
DgiDB (Drug Gene Interaction Database)GNAT2
DoCM (Curated mutations)GNAT2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GNAT2 (select a term)
intoGenGNAT2
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)1:110145889-110155705  ENSG00000134183
CONAN: Copy Number AnalysisGNAT2 
Mutations and Diseases : HGMDGNAT2
OMIM139340    613856   
MedgenGNAT2
Genetic Testing Registry GNAT2
NextProtP19087 [Medical]
TSGene2780
GENETestsGNAT2
Huge Navigator GNAT2 [HugePedia]
snp3D : Map Gene to Disease2780
BioCentury BCIQGNAT2
ClinGenGNAT2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2780
Chemical/Pharm GKB GenePA28774
Clinical trialGNAT2
Miscellaneous
canSAR (ICR)GNAT2 (select the gene name)
Probes
Litterature
PubMed35 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGNAT2
EVEXGNAT2
GoPubMedGNAT2
iHOPGNAT2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 19 18:51:11 CEST 2016

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