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GNAT3 (G protein subunit alpha transducin 3)

Identity

Alias_namesguanine nucleotide binding protein, alpha transducing 3
Alias_symbol (synonym)gustducin
GDCA
Other alias
HGNC (Hugo) GNAT3
LocusID (NCBI) 346562
Atlas_Id 63860
Location 7q21.11  [Link to chromosome band 7q21]
Location_base_pair Starts at 80458635 and ends at 80512009 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GNAT3   22800
Cards
Entrez_Gene (NCBI)GNAT3  346562  G protein subunit alpha transducin 3
AliasesGDCA
GeneCards (Weizmann)GNAT3
Ensembl hg19 (Hinxton)ENSG00000214415 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000214415 [Gene_View]  chr7:80458635-80512009 [Contig_View]  GNAT3 [Vega]
ICGC DataPortalENSG00000214415
TCGA cBioPortalGNAT3
AceView (NCBI)GNAT3
Genatlas (Paris)GNAT3
WikiGenes346562
SOURCE (Princeton)GNAT3
Genetics Home Reference (NIH)GNAT3
Genomic and cartography
GoldenPath hg38 (UCSC)GNAT3  -     chr7:80458635-80512009 -  7q21.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GNAT3  -     7q21.11   [Description]    (hg19-Feb_2009)
EnsemblGNAT3 - 7q21.11 [CytoView hg19]  GNAT3 - 7q21.11 [CytoView hg38]
Mapping of homologs : NCBIGNAT3 [Mapview hg19]  GNAT3 [Mapview hg38]
OMIM139395   
Gene and transcription
Genbank (Entrez)BC147016 BC147017
RefSeq transcript (Entrez)NM_001102386
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GNAT3
Cluster EST : UnigeneHs.335049 [ NCBI ]
CGAP (NCI)Hs.335049
Alternative Splicing GalleryENSG00000214415
Gene ExpressionGNAT3 [ NCBI-GEO ]   GNAT3 [ EBI - ARRAY_EXPRESS ]   GNAT3 [ SEEK ]   GNAT3 [ MEM ]
Gene Expression Viewer (FireBrowse)GNAT3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)346562
GTEX Portal (Tissue expression)GNAT3
Human Protein AtlasENSG00000214415-GNAT3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtA8MTJ3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtA8MTJ3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProA8MTJ3
Splice isoforms : SwissVarA8MTJ3
PhosPhoSitePlusA8MTJ3
Domains : Interpro (EBI)Gprotein_alpha_I    Gprotein_alpha_su    GproteinA_insert    P-loop_NTPase   
Domain families : Pfam (Sanger)G-alpha (PF00503)   
Domain families : Pfam (NCBI)pfam00503   
Domain families : Smart (EMBL)G_alpha (SM00275)  
Conserved Domain (NCBI)GNAT3
DMDM Disease mutations346562
Blocks (Seattle)GNAT3
SuperfamilyA8MTJ3
Human Protein Atlas [tissue]ENSG00000214415-GNAT3 [tissue]
Peptide AtlasA8MTJ3
IPIIPI00248911   
Protein Interaction databases
DIP (DOE-UCLA)A8MTJ3
IntAct (EBI)A8MTJ3
FunCoupENSG00000214415
BioGRIDGNAT3
STRING (EMBL)GNAT3
ZODIACGNAT3
Ontologies - Pathways
QuickGOA8MTJ3
Ontology : AmiGOdetection of chemical stimulus involved in sensory perception of bitter taste  G-protein coupled receptor binding  acrosomal vesicle  photoreceptor outer segment  photoreceptor inner segment  GTPase activity  GTPase activity  signal transducer activity  GTP binding  heterotrimeric G-protein complex  plasma membrane  axoneme  protein folding  adenylate cyclase-modulating G-protein coupled receptor signaling pathway  adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway  apical plasma membrane  G-protein beta/gamma-subunit complex binding  response to nicotine  protein complex  metal ion binding  sensory perception of sweet taste  sensory perception of umami taste  
Ontology : EGO-EBIdetection of chemical stimulus involved in sensory perception of bitter taste  G-protein coupled receptor binding  acrosomal vesicle  photoreceptor outer segment  photoreceptor inner segment  GTPase activity  GTPase activity  signal transducer activity  GTP binding  heterotrimeric G-protein complex  plasma membrane  axoneme  protein folding  adenylate cyclase-modulating G-protein coupled receptor signaling pathway  adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway  apical plasma membrane  G-protein beta/gamma-subunit complex binding  response to nicotine  protein complex  metal ion binding  sensory perception of sweet taste  sensory perception of umami taste  
Pathways : KEGGTaste transduction    Phototransduction    Carbohydrate digestion and absorption   
NDEx NetworkGNAT3
Atlas of Cancer Signalling NetworkGNAT3
Wikipedia pathwaysGNAT3
Orthology - Evolution
OrthoDB346562
GeneTree (enSembl)ENSG00000214415
Phylogenetic Trees/Animal Genes : TreeFamGNAT3
HOVERGENA8MTJ3
HOGENOMA8MTJ3
Homologs : HomoloGeneGNAT3
Homology/Alignments : Family Browser (UCSC)GNAT3
Gene fusions - Rearrangements
Tumor Fusion PortalGNAT3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGNAT3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GNAT3
dbVarGNAT3
ClinVarGNAT3
1000_GenomesGNAT3 
Exome Variant ServerGNAT3
ExAC (Exome Aggregation Consortium)ENSG00000214415
GNOMAD BrowserENSG00000214415
Genetic variants : HAPMAP346562
Genomic Variants (DGV)GNAT3 [DGVbeta]
DECIPHERGNAT3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGNAT3 
Mutations
ICGC Data PortalGNAT3 
TCGA Data PortalGNAT3 
Broad Tumor PortalGNAT3
OASIS PortalGNAT3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGNAT3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGNAT3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GNAT3
DgiDB (Drug Gene Interaction Database)GNAT3
DoCM (Curated mutations)GNAT3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GNAT3 (select a term)
intoGenGNAT3
Cancer3DGNAT3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM139395   
Orphanet
DisGeNETGNAT3
MedgenGNAT3
Genetic Testing Registry GNAT3
NextProtA8MTJ3 [Medical]
TSGene346562
GENETestsGNAT3
Target ValidationGNAT3
Huge Navigator GNAT3 [HugePedia]
snp3D : Map Gene to Disease346562
BioCentury BCIQGNAT3
ClinGenGNAT3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD346562
Chemical/Pharm GKB GenePA134931156
Clinical trialGNAT3
Miscellaneous
canSAR (ICR)GNAT3 (select the gene name)
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGNAT3
EVEXGNAT3
GoPubMedGNAT3
iHOPGNAT3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 13:16:10 CET 2017

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