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GNAZ (G protein subunit alpha z)

Identity

Alias_namesguanine nucleotide binding protein (G protein)
Other aliasgz-alpha
HGNC (Hugo) GNAZ
LocusID (NCBI) 2781
Atlas_Id 43283
Location 22q11.22  [Link to chromosome band 22q11]
Location_base_pair Starts at 23070349 and ends at 23125037 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
BCR (22q11.23) / GNAZ (22q11.22)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GNAZ   4395
Cards
Entrez_Gene (NCBI)GNAZ  2781  G protein subunit alpha z
Aliasesgz-alpha
GeneCards (Weizmann)GNAZ
Ensembl hg19 (Hinxton)ENSG00000128266 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000128266 [Gene_View]  chr22:23070349-23125037 [Contig_View]  GNAZ [Vega]
ICGC DataPortalENSG00000128266
TCGA cBioPortalGNAZ
AceView (NCBI)GNAZ
Genatlas (Paris)GNAZ
WikiGenes2781
SOURCE (Princeton)GNAZ
Genetics Home Reference (NIH)GNAZ
Genomic and cartography
GoldenPath hg38 (UCSC)GNAZ  -     chr22:23070349-23125037 +  22q11.22   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GNAZ  -     22q11.22   [Description]    (hg19-Feb_2009)
EnsemblGNAZ - 22q11.22 [CytoView hg19]  GNAZ - 22q11.22 [CytoView hg38]
Mapping of homologs : NCBIGNAZ [Mapview hg19]  GNAZ [Mapview hg38]
OMIM139160   
Gene and transcription
Genbank (Entrez)AF493899 AK126747 AK293653 AK309397 AK312519
RefSeq transcript (Entrez)NM_002073
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GNAZ
Cluster EST : UnigeneHs.584760 [ NCBI ]
CGAP (NCI)Hs.584760
Alternative Splicing GalleryENSG00000128266
Gene ExpressionGNAZ [ NCBI-GEO ]   GNAZ [ EBI - ARRAY_EXPRESS ]   GNAZ [ SEEK ]   GNAZ [ MEM ]
Gene Expression Viewer (FireBrowse)GNAZ [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2781
GTEX Portal (Tissue expression)GNAZ
Human Protein AtlasENSG00000128266-GNAZ [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP19086   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP19086  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP19086
Splice isoforms : SwissVarP19086
PhosPhoSitePlusP19086
Domains : Interpro (EBI)Gprotein_alpha_I    Gprotein_alpha_su    GproteinA_insert    P-loop_NTPase   
Domain families : Pfam (Sanger)G-alpha (PF00503)   
Domain families : Pfam (NCBI)pfam00503   
Domain families : Smart (EMBL)G_alpha (SM00275)  
Conserved Domain (NCBI)GNAZ
DMDM Disease mutations2781
Blocks (Seattle)GNAZ
SuperfamilyP19086
Human Protein Atlas [tissue]ENSG00000128266-GNAZ [tissue]
Peptide AtlasP19086
HPRD00746
IPIIPI00328128   IPI01011503   
Protein Interaction databases
DIP (DOE-UCLA)P19086
IntAct (EBI)P19086
FunCoupENSG00000128266
BioGRIDGNAZ
STRING (EMBL)GNAZ
ZODIACGNAZ
Ontologies - Pathways
QuickGOP19086
Ontology : AmiGOG-protein coupled receptor binding  GTPase activity  GTPase activity  signal transducer activity, downstream of receptor  GTP binding  nuclear envelope  endoplasmic reticulum  cytosol  heterotrimeric G-protein complex  plasma membrane  protein folding  G-protein coupled receptor signaling pathway  adenylate cyclase-modulating G-protein coupled receptor signaling pathway  adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway  dendrite  G-protein beta/gamma-subunit complex binding  G-protein coupled serotonin receptor binding  cell body  metal ion binding  extracellular exosome  
Ontology : EGO-EBIG-protein coupled receptor binding  GTPase activity  GTPase activity  signal transducer activity, downstream of receptor  GTP binding  nuclear envelope  endoplasmic reticulum  cytosol  heterotrimeric G-protein complex  plasma membrane  protein folding  G-protein coupled receptor signaling pathway  adenylate cyclase-modulating G-protein coupled receptor signaling pathway  adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway  dendrite  G-protein beta/gamma-subunit complex binding  G-protein coupled serotonin receptor binding  cell body  metal ion binding  extracellular exosome  
Pathways : KEGGLong-term depression   
NDEx NetworkGNAZ
Atlas of Cancer Signalling NetworkGNAZ
Wikipedia pathwaysGNAZ
Orthology - Evolution
OrthoDB2781
GeneTree (enSembl)ENSG00000128266
Phylogenetic Trees/Animal Genes : TreeFamGNAZ
HOVERGENP19086
HOGENOMP19086
Homologs : HomoloGeneGNAZ
Homology/Alignments : Family Browser (UCSC)GNAZ
Gene fusions - Rearrangements
Tumor Fusion PortalGNAZ
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGNAZ [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GNAZ
dbVarGNAZ
ClinVarGNAZ
1000_GenomesGNAZ 
Exome Variant ServerGNAZ
ExAC (Exome Aggregation Consortium)ENSG00000128266
GNOMAD BrowserENSG00000128266
Genetic variants : HAPMAP2781
Genomic Variants (DGV)GNAZ [DGVbeta]
DECIPHERGNAZ [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGNAZ 
Mutations
ICGC Data PortalGNAZ 
TCGA Data PortalGNAZ 
Broad Tumor PortalGNAZ
OASIS PortalGNAZ [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGNAZ  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGNAZ
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GNAZ
DgiDB (Drug Gene Interaction Database)GNAZ
DoCM (Curated mutations)GNAZ (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GNAZ (select a term)
intoGenGNAZ
Cancer3DGNAZ(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM139160   
Orphanet
DisGeNETGNAZ
MedgenGNAZ
Genetic Testing Registry GNAZ
NextProtP19086 [Medical]
TSGene2781
GENETestsGNAZ
Target ValidationGNAZ
Huge Navigator GNAZ [HugePedia]
snp3D : Map Gene to Disease2781
BioCentury BCIQGNAZ
ClinGenGNAZ
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2781
Chemical/Pharm GKB GenePA28775
Clinical trialGNAZ
Miscellaneous
canSAR (ICR)GNAZ (select the gene name)
Probes
Litterature
PubMed48 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGNAZ
EVEXGNAZ
GoPubMedGNAZ
iHOPGNAZ
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:14:51 CET 2017

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