GNB1 (guanine nucleotide binding protein (G protein), beta polypeptide 1)

Identity

Other names	-
HGNC	GNB1
Location	1p36.33
Location_base_pair	Starts at 1706589 and ends at 1812355 bp from pter (hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	GNB1   4396
Entrez_Gene	GNB1  2782  guanine nucleotide binding protein (G protein), beta polypeptide 1
	Cards
GeneCards	GNB1
Ensembl	GNB1 [Search_View]   ENSG00000078369 [Gene_View]
Genatlas	GNB1
GeneLynx	GNB1
eGenome	GNB1
euGene	2782
	Genomic and cartography
GoldenPath	GNB1  -  1p36.33   chr1:1706589-1812355 -  1p36.33   [Description]    (hg18-March_2006)
Ensembl	GNB1 - 1p36.33 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	GNB1
	Gene and transcription
Genbank	AF070597 [ ENTREZ ]
Genbank	AF070603 [ ENTREZ ]
Genbank	AF501882 [ ENTREZ ]
Genbank	AK096614 [ ENTREZ ]
Genbank	AK122949 [ ENTREZ ]
RefSeq	NM_002074 [ SRS ]    NM_002074 [ ENTREZ ]
RefSeq	AC_000044 [ SRS ]    AC_000044 [ ENTREZ ]
RefSeq	AC_000133 [ SRS ]    AC_000133 [ ENTREZ ]
RefSeq	NC_000001 [ SRS ]    NC_000001 [ ENTREZ ]
RefSeq	NT_004350 [ SRS ]    NT_004350 [ ENTREZ ]
RefSeq	NW_001838585 [ SRS ]    NW_001838585 [ ENTREZ ]
RefSeq	NW_921350 [ SRS ]    NW_921350 [ ENTREZ ]
AceView	GNB1 AceView - NCBI
Unigene	Hs.709208 [ SRS ]    Hs.709208 [ NCBI ]     HS709208 [ spliceNest ]
Fast-db	18013 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P62873 [ SRS]    P62873 [ EXPASY ]     P62873 [ INTERPRO ]     P62873 [ UNIPROT ]
Prosite	PS00678 WD_REPEATS_1 [ SRS ]    PS00678 WD_REPEATS_1 [ Expasy ]
Prosite	PS50082 WD_REPEATS_2 [ SRS ]    PS50082 WD_REPEATS_2 [ Expasy ]
Prosite	PS50294 WD_REPEATS_REGION [ SRS ]    PS50294 WD_REPEATS_REGION [ Expasy ]
Interpro	IPR001632 Gprotein_B [ SRS ]    IPR001632 Gprotein_B [ EBI ]
Interpro	IPR016346 Guanine_nucleotide-bd_bsu [ SRS ]    IPR016346 Guanine_nucleotide-bd_bsu [ EBI ]
Interpro	IPR015943 WD40/YVTN_repeat-like [ SRS ]    IPR015943 WD40/YVTN_repeat-like [ EBI ]
Interpro	IPR001680 WD40_repeat [ SRS ]    IPR001680 WD40_repeat [ EBI ]
CluSTr	P62873
Pfam	PF00400 WD40 [ SRS ]    PF00400 WD40 [ Sanger ]    pfam00400 [ NCBI-CDD ]
Smart	SM00320 WD40 [EMBL]
Prodom	PD000018 WD40[INRA-Toulouse]
Prodom	P62873 GBB1_HUMAN [ Domain structure ]   P62873 GBB1_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	P62873
HPRD	00766
	Protein Interaction databases
DIP	P62873
IntAct	P62873
	Polymorphism : SNP, mutations, diseases
OMIM	139380    [ map ]
GENECLINICS	139380
SNP	GNB1 [dbSNP-NCBI]
SNP	NM_002074 [SNP-NCI]
SNP	GNB1 [GeneSNPs - Utah]  GNB1] [HGBASE - SRS]
HAPMAP	GNB1 [HAPMAP]
COSMIC	GNB1 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	GNB1
	General knowledge
Family Browser	GNB1 [UCSC Family Browser]
SOURCE	NM_002074
SMD	Hs.709208
SAGE	Hs.709208
GO	GTPase activity [Amigo]  GTPase activity
GO	signal transducer activity [Amigo]  signal transducer activity
GO	signal transduction [Amigo]  signal transduction
GO	acetylcholine receptor signaling, muscarinic pathway [Amigo]  acetylcholine receptor signaling, muscarinic pathway
GO	Ras protein signal transduction [Amigo]  Ras protein signal transduction
GO	hormone-mediated signaling [Amigo]  hormone-mediated signaling
BIOCARTA	CCR3 signaling in Eosinophils    [Genes]
BIOCARTA	Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor    [Genes]
BIOCARTA	Thrombin signaling and protease-activated receptors    [Genes]
BIOCARTA	Attenuation of GPCR Signaling    [Genes]
BIOCARTA	Roles of §-arrestin-dependent Recruitment of Src Kinases in GPCR Signaling    [Genes]
BIOCARTA	§-arrestins in GPCR Desensitization    [Genes]
BIOCARTA	Role of §-arrestins in the activation and targeting of MAP kinases    [Genes]
BIOCARTA	Bioactive Peptide Induced Signaling Pathway    [Genes]
BIOCARTA	ChREBP regulation by carbohydrates and cAMP    [Genes]
BIOCARTA	CXCR4 Signaling Pathway    [Genes]
BIOCARTA	Phospholipids as signalling intermediaries    [Genes]
BIOCARTA	Erk1/Erk2 Mapk Signaling pathway    [Genes]
BIOCARTA	fMLP induced chemokine gene expression in HMC-1 cells    [Genes]
BIOCARTA	Corticosteroids and cardioprotection    [Genes]
BIOCARTA	Signaling Pathway from G-Protein Families    [Genes]
BIOCARTA	Activation of cAMP-dependent protein kinase, PKA    [Genes]
BIOCARTA	How Progesterone Initiates the Oocyte Maturation    [Genes]
BIOCARTA	PKC-catalyzed phosphorylation of inhibitory phosphoprotein of myosin phosphatase    [Genes]
BIOCARTA	Ion Channels and Their Functional Role in Vascular Endothelium    [Genes]
BIOCARTA	Aspirin Blocks Signaling Pathway Involved in Platelet Activation    [Genes]
BIOCARTA	G-Protein Signaling Through Tubby Proteins    [Genes]
KEGG	Taste transduction
PubGene	GNB1
TreeFam	GNB1
CTD	2782 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	GNB1 Related clones (RZPD - Berlin)
	PubMed
PubMed	51 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 11 13:14:52 2008