GNB1L (G protein subunit beta 1 like)

2003-05-01  

Identity

HGNC
LOCATION
22q11.21
LOCUSID
ALIAS
DGCRK3,FKSG1,GY2,WDR14,WDVCF
FUSION GENES

Other Information

Locus ID:

NCBI: 54584
MIM: 610778
HGNC: 4397
Ensembl: ENSG00000185838

Variants:

dbSNP: 54584
ClinVar: 54584
TCGA: ENSG00000185838
COSMIC: GNB1L

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000185838ENST00000329517Q9BYB4
ENSG00000185838ENST00000403325Q9BYB4
ENSG00000185838ENST00000405009Q9BYB4
ENSG00000185838ENST00000453108C9JPQ6

Expression (GTEx)

0
1
2
3
4

Protein levels (Protein atlas)

Not detected
Low
Medium
High

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA33384PLCB1GenePathwayassociated
PA33385PLCB2GenePathwayassociated
PA33386PLCB3GenePathwayassociated
PA33387PLCB4GenePathwayassociated

References

Pubmed IDYearTitleCitations
180036362008Strong evidence that GNB1L is associated with schizophrenia.23
180036362008Strong evidence that GNB1L is associated with schizophrenia.23
190112332010Supportive evidence for reduced expression of GNB1L in schizophrenia.9
190112332010Supportive evidence for reduced expression of GNB1L in schizophrenia.9
205383452011Association study between GNB1L and three major mental disorders in Chinese Han populations.5
205383452011Association study between GNB1L and three major mental disorders in Chinese Han populations.5
187552692008GbetaL regulates TNFalpha-induced NF-kappaB signaling by directly inhibiting the activation of IkappaB kinase.3
208604622010β-blocker therapy and heart rate control during exercise testing in the general population: role of a common G-protein β-3 subunit variant.2
248314362015The schizophrenia/bipolar disorder candidate gene GNB1L is regulated in human temporal cortex by a cis-acting element located within the 3'-region.1

Citation

Dessen P

GNB1L (G protein subunit beta 1 like)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/40729/gnb1l