Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2783
MIM: 139390
HGNC: 4398
Ensembl: ENSG00000172354
Variants:
dbSNP: 2783
ClinVar: 2783
TCGA: ENSG00000172354
COSMIC: GNB2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA33384 | PLCB1 | Gene | Pathway | associated | |||
| PA33385 | PLCB2 | Gene | Pathway | associated | |||
| PA33386 | PLCB3 | Gene | Pathway | associated | |||
| PA33387 | PLCB4 | Gene | Pathway | associated |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35730811 | 2022 | A detailed multi-omics analysis of GNB2 gene in human cancers. | 14 |
| 35730811 | 2022 | A detailed multi-omics analysis of GNB2 gene in human cancers. | 14 |
| 34124757 | 2021 | A novel somatic mutation in GNB2 provides new insights to the pathogenesis of Sturge-Weber syndrome. | 10 |
| 34124757 | 2021 | A novel somatic mutation in GNB2 provides new insights to the pathogenesis of Sturge-Weber syndrome. | 10 |
| 28219978 | 2017 | A Mutation in the G-Protein Gene GNB2 Causes Familial Sinus Node and Atrioventricular Conduction Dysfunction. | 26 |
| 28219978 | 2017 | A Mutation in the G-Protein Gene GNB2 Causes Familial Sinus Node and Atrioventricular Conduction Dysfunction. | 26 |
| 25485910 | 2015 | Mutations in G protein β subunits promote transformation and kinase inhibitor resistance. | 41 |
| 25485910 | 2015 | Mutations in G protein β subunits promote transformation and kinase inhibitor resistance. | 41 |
| 22917497 | 2012 | Serum starvation activates NF-κB through G protein β2 subunit-mediated signal. | 6 |
| 23043599 | 2012 | Identification of cellular proteins interacting with influenza A virus PB1-F2 protein. | 6 |
| 22917497 | 2012 | Serum starvation activates NF-κB through G protein β2 subunit-mediated signal. | 6 |
| 23043599 | 2012 | Identification of cellular proteins interacting with influenza A virus PB1-F2 protein. | 6 |
| 20381070 | 2010 | Sex-specific proteome differences in the anterior cingulate cortex of schizophrenia. | 29 |
| 20381070 | 2010 | Sex-specific proteome differences in the anterior cingulate cortex of schizophrenia. | 29 |
| 16973746 | 2006 | The molecular basis for T-type Ca2+ channel inhibition by G protein beta2gamma2 subunits. | 20 |
Citation
Dessen P
GNB2 (G protein subunit beta 2)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43284/gnb2
