Atlas of Genetics and Cytogenetics in Oncology and Haematology


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GNE (glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase)

Identity

Other namesDMRV
GLCNE
IBM2
NM
Uae1
HGNC (Hugo) GNE
LocusID (NCBI) 10020
Location 9p13.3
Location_base_pair Starts at 36214439 and ends at 36277053 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)GNE   23657
Cards
Entrez_Gene (NCBI)GNE  10020  glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GeneCards (Weizmann)GNE
Ensembl (Hinxton)ENSG00000159921 [Gene_View]  chr9:36214439-36277053 [Contig_View]  GNE [Vega]
ICGC DataPortalENSG00000159921
cBioPortalGNE
AceView (NCBI)GNE
Genatlas (Paris)GNE
WikiGenes10020
SOURCE (Princeton)NM_001128227 NM_001190383 NM_001190384 NM_001190388 NM_005476
Genomic and cartography
GoldenPath (UCSC)GNE  -  9p13.3   chr9:36214439-36277053 -  9p13.3   [Description]    (hg19-Feb_2009)
EnsemblGNE - 9p13.3 [CytoView]
Mapping of homologs : NCBIGNE [Mapview]
OMIM269921   600737   603824   605820   
Gene and transcription
Genbank (Entrez)AF051852 AF155663 AJ238764 AK295562 AK296687
RefSeq transcript (Entrez)NM_001128227 NM_001190383 NM_001190384 NM_001190388 NM_005476
RefSeq genomic (Entrez)AC_000141 NC_000009 NC_018920 NG_008246 NT_008413 NW_001839151 NW_004929342
Consensus coding sequences : CCDS (NCBI)GNE
Cluster EST : UnigeneHs.5920 [ NCBI ]
CGAP (NCI)Hs.5920
Alternative Splicing : Fast-db (Paris)GSHG0030800
Alternative Splicing GalleryENSG00000159921
Gene ExpressionGNE [ NCBI-GEO ]     GNE [ SEEK ]   GNE [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y223 (Uniprot)
NextProtQ9Y223  [Medical]
With graphics : InterProQ9Y223
Splice isoforms : SwissVarQ9Y223 (Swissvar)
Catalytic activity : Enzyme3.2.1.183 [ Enzyme-Expasy ]   3.2.1.1833.2.1.183 [ IntEnz-EBI ]   3.2.1.183 [ BRENDA ]   3.2.1.183 [ KEGG ]   
Domains : Interpro (EBI)Hexokinase [organisation]   ROK [organisation]   UDP-GlcNAc_Epase [organisation]   UDP_GlcNAc_Epimerase_2 [organisation]  
Related proteins : CluSTrQ9Y223
Domain families : Pfam (Sanger)Epimerase_2 (PF02350)    ROK (PF00480)   
Domain families : Pfam (NCBI)pfam02350    pfam00480   
DMDM Disease mutations10020
Blocks (Seattle)Q9Y223
PDB (SRS)2YHW    2YHY    2YI1    3EO3   
PDB (PDBSum)2YHW    2YHY    2YI1    3EO3   
PDB (IMB)2YHW    2YHY    2YI1    3EO3   
PDB (RSDB)2YHW    2YHY    2YI1    3EO3   
Human Protein AtlasENSG00000159921 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasQ9Y223
HPRD04825
IPIIPI00023162   IPI00896504   IPI01018963   IPI00982551   IPI00922266   IPI00867674   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y223
IntAct (EBI)Q9Y223
FunCoupENSG00000159921
BioGRIDGNE
InParanoidQ9Y223
Interologous Interaction database Q9Y223
IntegromeDBGNE
STRING (EMBL)GNE
Ontologies - Pathways
Ontology : AmiGOATP binding  cytoplasm  cytosol  N-acetylglucosamine biosynthetic process  UDP-N-acetylglucosamine metabolic process  N-acetylneuraminate metabolic process  cell adhesion  UDP-N-acetylglucosamine 2-epimerase activity  lipopolysaccharide biosynthetic process  N-acylmannosamine kinase activity  hydrolase activity  N-acetylneuraminate biosynthetic process  carbohydrate phosphorylation  carbohydrate phosphorylation  metal ion binding  
Ontology : EGO-EBIATP binding  cytoplasm  cytosol  N-acetylglucosamine biosynthetic process  UDP-N-acetylglucosamine metabolic process  N-acetylneuraminate metabolic process  cell adhesion  UDP-N-acetylglucosamine 2-epimerase activity  lipopolysaccharide biosynthetic process  N-acylmannosamine kinase activity  hydrolase activity  N-acetylneuraminate biosynthetic process  carbohydrate phosphorylation  carbohydrate phosphorylation  metal ion binding  
Pathways : KEGGAmino sugar and nucleotide sugar metabolism   
Protein Interaction DatabaseGNE
Wikipedia pathwaysGNE
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)GNE
snp3D : Map Gene to Disease10020
SNP (GeneSNP Utah)GNE
SNP : HGBaseGNE
Genetic variants : HAPMAPGNE
Exome VariantGNE
1000_GenomesGNE 
ICGC programENSG00000159921 
Somatic Mutations in Cancer : COSMICGNE 
CONAN: Copy Number AnalysisGNE 
Mutations and Diseases : HGMDGNE
Genomic VariantsGNE  GNE [DGVbeta]
dbVarGNE
ClinVarGNE
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM269921    600737    603824    605820   
MedgenGNE
GENETestsGNE
Disease Genetic AssociationGNE
Huge Navigator GNE [HugePedia]  GNE [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneGNE
Homology/Alignments : Family Browser (UCSC)GNE
Phylogenetic Trees/Animal Genes : TreeFamGNE
Chemical/Protein Interactions : CTD10020
Chemical/Pharm GKB GenePA134987566
Clinical trialGNE
Cancer Resource (Charite)ENSG00000159921
Other databases
Probes
Litterature
PubMed86 Pubmed reference(s) in Entrez
CoreMineGNE
iHOPGNE
OncoSearchGNE
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jul 30 13:56:33 CEST 2014

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