Atlas of Genetics and Cytogenetics in Oncology and Haematology


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GNG2 (G protein subunit gamma 2)

Identity

Alias_namesguanine nucleotide binding protein (G protein)
Other alias-
HGNC (Hugo) GNG2
LocusID (NCBI) 54331
Atlas_Id 43293
Location 14q22.1  [Link to chromosome band 14q22]
Location_base_pair Starts at 52327022 and ends at 52436518 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
GNG2 (14q22.1) / GNG2 (14q22.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GNG2   4404
Cards
Entrez_Gene (NCBI)GNG2  54331  G protein subunit gamma 2
Aliases
GeneCards (Weizmann)GNG2
Ensembl hg19 (Hinxton)ENSG00000186469 [Gene_View]  chr14:52327022-52436518 [Contig_View]  GNG2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000186469 [Gene_View]  chr14:52327022-52436518 [Contig_View]  GNG2 [Vega]
ICGC DataPortalENSG00000186469
TCGA cBioPortalGNG2
AceView (NCBI)GNG2
Genatlas (Paris)GNG2
WikiGenes54331
SOURCE (Princeton)GNG2
Genetics Home Reference (NIH)GNG2
Genomic and cartography
GoldenPath hg19 (UCSC)GNG2  -     chr14:52327022-52436518 +  14q22.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)GNG2  -     14q22.1   [Description]    (hg38-Dec_2013)
EnsemblGNG2 - 14q22.1 [CytoView hg19]  GNG2 - 14q22.1 [CytoView hg38]
Mapping of homologs : NCBIGNG2 [Mapview hg19]  GNG2 [Mapview hg38]
OMIM606981   
Gene and transcription
Genbank (Entrez)AB074180 AF130106 AF493870 AK001024 AK026424
RefSeq transcript (Entrez)NM_001243773 NM_001243774 NM_053064
RefSeq genomic (Entrez)NC_000014 NC_018925 NT_026437 NW_004929393
Consensus coding sequences : CCDS (NCBI)GNG2
Cluster EST : UnigeneHs.741081 [ NCBI ]
CGAP (NCI)Hs.741081
Alternative Splicing GalleryENSG00000186469
Gene ExpressionGNG2 [ NCBI-GEO ]   GNG2 [ EBI - ARRAY_EXPRESS ]   GNG2 [ SEEK ]   GNG2 [ MEM ]
Gene Expression Viewer (FireBrowse)GNG2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54331
GTEX Portal (Tissue expression)GNG2
Protein : pattern, domain, 3D structure
UniProt/SwissProtP59768   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP59768  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP59768
Splice isoforms : SwissVarP59768
PhosPhoSitePlusP59768
Domaine pattern : Prosite (Expaxy)G_PROTEIN_GAMMA (PS50058)   
Domains : Interpro (EBI)G-protein_gamma-like_dom    Gprotein-gamma   
Domain families : Pfam (Sanger)G-gamma (PF00631)   
Domain families : Pfam (NCBI)pfam00631   
Domain families : Smart (EMBL)GGL (SM00224)  
Conserved Domain (NCBI)GNG2
DMDM Disease mutations54331
Blocks (Seattle)GNG2
PDB (SRS)4KFM   
PDB (PDBSum)4KFM   
PDB (IMB)4KFM   
PDB (RSDB)4KFM   
Structural Biology KnowledgeBase4KFM   
SCOP (Structural Classification of Proteins)4KFM   
CATH (Classification of proteins structures)4KFM   
SuperfamilyP59768
Human Protein AtlasENSG00000186469
Peptide AtlasP59768
HPRD16234
IPIIPI00470619   IPI00301173   IPI01024726   IPI01026472   IPI01026353   IPI01025193   IPI01025035   
Protein Interaction databases
DIP (DOE-UCLA)P59768
IntAct (EBI)P59768
FunCoupENSG00000186469
BioGRIDGNG2
STRING (EMBL)GNG2
ZODIACGNG2
Ontologies - Pathways
QuickGOP59768
Ontology : AmiGOsignal transducer activity  heterotrimeric G-protein complex  plasma membrane  protein folding  adenylate cyclase-activating dopamine receptor signaling pathway  Wnt signaling pathway, calcium modulating pathway  cell proliferation  membrane  platelet activation  G-protein beta-subunit binding  extracellular exosome  cellular response to glucagon stimulus  cellular response to prostaglandin E stimulus  cellular response to catecholamine stimulus  
Ontology : EGO-EBIsignal transducer activity  heterotrimeric G-protein complex  plasma membrane  protein folding  adenylate cyclase-activating dopamine receptor signaling pathway  Wnt signaling pathway, calcium modulating pathway  cell proliferation  membrane  platelet activation  G-protein beta-subunit binding  extracellular exosome  cellular response to glucagon stimulus  cellular response to prostaglandin E stimulus  cellular response to catecholamine stimulus  
Pathways : KEGGRas signaling pathway    Chemokine signaling pathway    PI3K-Akt signaling pathway    Circadian entrainment    Retrograde endocannabinoid signaling    Glutamatergic synapse    Cholinergic synapse    Serotonergic synapse    GABAergic synapse    Dopaminergic synapse    Morphine addiction    Alcoholism   
NDEx NetworkGNG2
Atlas of Cancer Signalling NetworkGNG2
Wikipedia pathwaysGNG2
Orthology - Evolution
OrthoDB54331
GeneTree (enSembl)ENSG00000186469
Phylogenetic Trees/Animal Genes : TreeFamGNG2
HOVERGENP59768
HOGENOMP59768
Homologs : HomoloGeneGNG2
Homology/Alignments : Family Browser (UCSC)GNG2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGNG2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GNG2
dbVarGNG2
ClinVarGNG2
1000_GenomesGNG2 
Exome Variant ServerGNG2
ExAC (Exome Aggregation Consortium)GNG2 (select the gene name)
Genetic variants : HAPMAP54331
Genomic Variants (DGV)GNG2 [DGVbeta]
DECIPHER (Syndromes)14:52327022-52436518  ENSG00000186469
CONAN: Copy Number AnalysisGNG2 
Mutations
ICGC Data PortalGNG2 
TCGA Data PortalGNG2 
Broad Tumor PortalGNG2
OASIS PortalGNG2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGNG2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGNG2
intOGen PortalGNG2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GNG2
DgiDB (Drug Gene Interaction Database)GNG2
DoCM (Curated mutations)GNG2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GNG2 (select a term)
intoGenGNG2
Cancer3DGNG2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606981   
Orphanet
MedgenGNG2
Genetic Testing Registry GNG2
NextProtP59768 [Medical]
TSGene54331
GENETestsGNG2
Huge Navigator GNG2 [HugePedia]
snp3D : Map Gene to Disease54331
BioCentury BCIQGNG2
ClinGenGNG2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54331
Chemical/Pharm GKB GenePA28784
Clinical trialGNG2
Miscellaneous
canSAR (ICR)GNG2 (select the gene name)
Probes
Litterature
PubMed74 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGNG2
EVEXGNG2
GoPubMedGNG2
iHOPGNG2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 30 15:02:40 CEST 2017

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