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GNG5 (G protein subunit gamma 5)

Identity

Alias_namesguanine nucleotide binding protein (G protein)
Other alias-
HGNC (Hugo) GNG5
LocusID (NCBI) 2787
Atlas_Id 43295
Location 1p22.3  [Link to chromosome band 1p22]
Location_base_pair Starts at 84964006 and ends at 84972262 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
CTBS (1p22.3) / GNG5 (1p22.3)GNG5 (1p22.3) / CTBS (1p22.3)RPF1 (1p22.3) / GNG5 (1p22.3)
TTLL7 (1p31.1) / GNG5 (1p22.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GNG5   4408
Cards
Entrez_Gene (NCBI)GNG5  2787  G protein subunit gamma 5
Aliases
GeneCards (Weizmann)GNG5
Ensembl hg19 (Hinxton)ENSG00000174021 [Gene_View]  chr1:84964006-84972262 [Contig_View]  GNG5 [Vega]
Ensembl hg38 (Hinxton)ENSG00000174021 [Gene_View]  chr1:84964006-84972262 [Contig_View]  GNG5 [Vega]
ICGC DataPortalENSG00000174021
TCGA cBioPortalGNG5
AceView (NCBI)GNG5
Genatlas (Paris)GNG5
WikiGenes2787
SOURCE (Princeton)GNG5
Genetics Home Reference (NIH)GNG5
Genomic and cartography
GoldenPath hg19 (UCSC)GNG5  -     chr1:84964006-84972262 -  1p22.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)GNG5  -     1p22.3   [Description]    (hg38-Dec_2013)
EnsemblGNG5 - 1p22.3 [CytoView hg19]  GNG5 - 1p22.3 [CytoView hg38]
Mapping of homologs : NCBIGNG5 [Mapview hg19]  GNG5 [Mapview hg38]
OMIM600874   
Gene and transcription
Genbank (Entrez)AF038955 AF493873 AK312111 BC003563 BM809260
RefSeq transcript (Entrez)NM_005274
RefSeq genomic (Entrez)NC_000001 NC_018912 NT_032977 NW_004929290
Consensus coding sequences : CCDS (NCBI)GNG5
Cluster EST : UnigeneHs.645427 [ NCBI ]
CGAP (NCI)Hs.645427
Alternative Splicing GalleryENSG00000174021
Gene ExpressionGNG5 [ NCBI-GEO ]   GNG5 [ EBI - ARRAY_EXPRESS ]   GNG5 [ SEEK ]   GNG5 [ MEM ]
Gene Expression Viewer (FireBrowse)GNG5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2787
GTEX Portal (Tissue expression)GNG5
Protein : pattern, domain, 3D structure
UniProt/SwissProtP63218   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP63218  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP63218
Splice isoforms : SwissVarP63218
PhosPhoSitePlusP63218
Domaine pattern : Prosite (Expaxy)G_PROTEIN_GAMMA (PS50058)   
Domains : Interpro (EBI)G-protein_gamma-like_dom    Gprotein-gamma   
Domain families : Pfam (Sanger)G-gamma (PF00631)   
Domain families : Pfam (NCBI)pfam00631   
Domain families : Smart (EMBL)GGL (SM00224)  
Conserved Domain (NCBI)GNG5
DMDM Disease mutations2787
Blocks (Seattle)GNG5
SuperfamilyP63218
Human Protein AtlasENSG00000174021
Peptide AtlasP63218
HPRD11865
IPIIPI00027240   
Protein Interaction databases
DIP (DOE-UCLA)P63218
IntAct (EBI)P63218
FunCoupENSG00000174021
BioGRIDGNG5
STRING (EMBL)GNG5
ZODIACGNG5
Ontologies - Pathways
QuickGOP63218
Ontology : AmiGOGTPase activity  signal transducer activity  protein binding  mitochondrion  heterotrimeric G-protein complex  plasma membrane  signal transduction  G-protein coupled receptor signaling pathway  membrane  PDZ domain binding  extracellular exosome  cellular response to glucagon stimulus  positive regulation of secondary heart field cardioblast proliferation  positive regulation of neural precursor cell proliferation  
Ontology : EGO-EBIGTPase activity  signal transducer activity  protein binding  mitochondrion  heterotrimeric G-protein complex  plasma membrane  signal transduction  G-protein coupled receptor signaling pathway  membrane  PDZ domain binding  extracellular exosome  cellular response to glucagon stimulus  positive regulation of secondary heart field cardioblast proliferation  positive regulation of neural precursor cell proliferation  
Pathways : KEGGRas signaling pathway    Chemokine signaling pathway    PI3K-Akt signaling pathway    Circadian entrainment    Retrograde endocannabinoid signaling    Glutamatergic synapse    Cholinergic synapse    Serotonergic synapse    GABAergic synapse    Dopaminergic synapse    Morphine addiction    Alcoholism   
NDEx NetworkGNG5
Atlas of Cancer Signalling NetworkGNG5
Wikipedia pathwaysGNG5
Orthology - Evolution
OrthoDB2787
GeneTree (enSembl)ENSG00000174021
Phylogenetic Trees/Animal Genes : TreeFamGNG5
HOVERGENP63218
HOGENOMP63218
Homologs : HomoloGeneGNG5
Homology/Alignments : Family Browser (UCSC)GNG5
Gene fusions - Rearrangements
Fusion Cancer (Beijing)CTBS [1p22.3]  -  GNG5 [1p22.3]  [FUSC000003]  [FUSC000003]  [FUSC000003]  [FUSC000003]  [FUSC000003]  [FUSC000003]  [FUSC000003]  [FUSC000003]  [FUSC000003]
Fusion Cancer (Beijing)GNG5 [1p22.3]  -  CTBS [1p22.3]  [FUSC000010]  [FUSC000010]  [FUSC000010]  [FUSC000010]  [FUSC000010]  [FUSC000010]  [FUSC000010]  [FUSC000010]  [FUSC000010]
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGNG5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GNG5
dbVarGNG5
ClinVarGNG5
1000_GenomesGNG5 
Exome Variant ServerGNG5
ExAC (Exome Aggregation Consortium)GNG5 (select the gene name)
Genetic variants : HAPMAP2787
Genomic Variants (DGV)GNG5 [DGVbeta]
DECIPHER (Syndromes)1:84964006-84972262  ENSG00000174021
CONAN: Copy Number AnalysisGNG5 
Mutations
ICGC Data PortalGNG5 
TCGA Data PortalGNG5 
Broad Tumor PortalGNG5
OASIS PortalGNG5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGNG5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGNG5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch GNG5
DgiDB (Drug Gene Interaction Database)GNG5
DoCM (Curated mutations)GNG5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GNG5 (select a term)
intoGenGNG5
Cancer3DGNG5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600874   
Orphanet
MedgenGNG5
Genetic Testing Registry GNG5
NextProtP63218 [Medical]
TSGene2787
GENETestsGNG5
Huge Navigator GNG5 [HugePedia]
snp3D : Map Gene to Disease2787
BioCentury BCIQGNG5
ClinGenGNG5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2787
Chemical/Pharm GKB GenePA28787
Clinical trialGNG5
Miscellaneous
canSAR (ICR)GNG5 (select the gene name)
Probes
Litterature
PubMed30 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGNG5
EVEXGNG5
GoPubMedGNG5
iHOPGNG5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 13:07:46 CET 2017

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