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GNGT1 (G protein subunit gamma transducin 1)

Identity

Alias_namesguanine nucleotide binding protein (G protein)
Alias_symbol (synonym)GNG1
Other alias
HGNC (Hugo) GNGT1
LocusID (NCBI) 2792
Atlas_Id 43297
Location 7q21.3  [Link to chromosome band 7q21]
Location_base_pair Starts at 93906508 and ends at 93911265 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
GNGT1 (7q21.3) / GLG1 (16q23.1)GNGT1 (7q21.3) / UBE2I (16p13.3)KRIT1 (7q21.2) / GNGT1 (7q21.3)
PARD3B (2q33.3) / GNGT1 (7q21.3)PPP1R21 (2p16.3) / GNGT1 (7q21.3)PSD3 (8p22) / GNGT1 (7q21.3)
TMCO3 (13q34) / GNGT1 (7q21.3)KRIT1 7q21.2 / GNGT1 7q21.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GNGT1   4411
Cards
Entrez_Gene (NCBI)GNGT1  2792  G protein subunit gamma transducin 1
AliasesGNG1
GeneCards (Weizmann)GNGT1
Ensembl hg19 (Hinxton)ENSG00000127928 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000127928 [Gene_View]  chr7:93906508-93911265 [Contig_View]  GNGT1 [Vega]
ICGC DataPortalENSG00000127928
TCGA cBioPortalGNGT1
AceView (NCBI)GNGT1
Genatlas (Paris)GNGT1
WikiGenes2792
SOURCE (Princeton)GNGT1
Genetics Home Reference (NIH)GNGT1
Genomic and cartography
GoldenPath hg38 (UCSC)GNGT1  -     chr7:93906508-93911265 +  7q21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GNGT1  -     7q21.3   [Description]    (hg19-Feb_2009)
EnsemblGNGT1 - 7q21.3 [CytoView hg19]  GNGT1 - 7q21.3 [CytoView hg38]
Mapping of homologs : NCBIGNGT1 [Mapview hg19]  GNGT1 [Mapview hg38]
OMIM189970   
Gene and transcription
Genbank (Entrez)AF493869 BC029367 BG435040 BQ637754 CR456912
RefSeq transcript (Entrez)NM_001329426 NM_021955
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GNGT1
Cluster EST : UnigeneHs.732212 [ NCBI ]
CGAP (NCI)Hs.732212
Alternative Splicing GalleryENSG00000127928
Gene ExpressionGNGT1 [ NCBI-GEO ]   GNGT1 [ EBI - ARRAY_EXPRESS ]   GNGT1 [ SEEK ]   GNGT1 [ MEM ]
Gene Expression Viewer (FireBrowse)GNGT1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2792
GTEX Portal (Tissue expression)GNGT1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP63211   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP63211  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP63211
Splice isoforms : SwissVarP63211
PhosPhoSitePlusP63211
Domaine pattern : Prosite (Expaxy)G_PROTEIN_GAMMA (PS50058)   
Domains : Interpro (EBI)G-protein_gamma-like_dom    Gprotein-gamma   
Domain families : Pfam (Sanger)G-gamma (PF00631)   
Domain families : Pfam (NCBI)pfam00631   
Domain families : Smart (EMBL)GGL (SM00224)  
Conserved Domain (NCBI)GNGT1
DMDM Disease mutations2792
Blocks (Seattle)GNGT1
SuperfamilyP63211
Human Protein AtlasENSG00000127928
Peptide AtlasP63211
HPRD01805
IPIIPI00221386   IPI00926907   
Protein Interaction databases
DIP (DOE-UCLA)P63211
IntAct (EBI)P63211
FunCoupENSG00000127928
BioGRIDGNGT1
STRING (EMBL)GNGT1
ZODIACGNGT1
Ontologies - Pathways
QuickGOP63211
Ontology : AmiGOphotoreceptor inner segment  GTPase activity  signal transducer activity  protein binding  heterotrimeric G-protein complex  plasma membrane  signal transduction  protein localization  cardiac muscle cell apoptotic process  rhodopsin mediated signaling pathway  regulation of rhodopsin mediated signaling pathway  eye photoreceptor cell development  cellular response to hypoxia  photoreceptor disc membrane  
Ontology : EGO-EBIphotoreceptor inner segment  GTPase activity  signal transducer activity  protein binding  heterotrimeric G-protein complex  plasma membrane  signal transduction  protein localization  cardiac muscle cell apoptotic process  rhodopsin mediated signaling pathway  regulation of rhodopsin mediated signaling pathway  eye photoreceptor cell development  cellular response to hypoxia  photoreceptor disc membrane  
Pathways : KEGG   
NDEx NetworkGNGT1
Atlas of Cancer Signalling NetworkGNGT1
Wikipedia pathwaysGNGT1
Orthology - Evolution
OrthoDB2792
GeneTree (enSembl)ENSG00000127928
Phylogenetic Trees/Animal Genes : TreeFamGNGT1
HOVERGENP63211
HOGENOMP63211
Homologs : HomoloGeneGNGT1
Homology/Alignments : Family Browser (UCSC)GNGT1
Gene fusions - Rearrangements
Fusion : MitelmanKRIT1/GNGT1 [7q21.2/7q21.3]  [t(7;7)(q21;q21)]  
Fusion: TCGAKRIT1 7q21.2 GNGT1 7q21.3 GBM
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGNGT1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GNGT1
dbVarGNGT1
ClinVarGNGT1
1000_GenomesGNGT1 
Exome Variant ServerGNGT1
ExAC (Exome Aggregation Consortium)GNGT1 (select the gene name)
Genetic variants : HAPMAP2792
Genomic Variants (DGV)GNGT1 [DGVbeta]
DECIPHERGNGT1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGNGT1 
Mutations
ICGC Data PortalGNGT1 
TCGA Data PortalGNGT1 
Broad Tumor PortalGNGT1
OASIS PortalGNGT1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGNGT1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGNGT1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GNGT1
DgiDB (Drug Gene Interaction Database)GNGT1
DoCM (Curated mutations)GNGT1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GNGT1 (select a term)
intoGenGNGT1
Cancer3DGNGT1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM189970   
Orphanet
MedgenGNGT1
Genetic Testing Registry GNGT1
NextProtP63211 [Medical]
TSGene2792
GENETestsGNGT1
Target ValidationGNGT1
Huge Navigator GNGT1 [HugePedia]
snp3D : Map Gene to Disease2792
BioCentury BCIQGNGT1
ClinGenGNGT1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2792
Chemical/Pharm GKB GenePA28790
Clinical trialGNGT1
Miscellaneous
canSAR (ICR)GNGT1 (select the gene name)
Probes
Litterature
PubMed31 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGNGT1
EVEXGNGT1
GoPubMedGNGT1
iHOPGNGT1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:35:35 CEST 2017

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