Atlas of Genetics and Cytogenetics in Oncology and Haematology


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GNL3 (G protein nucleolar 3)

Identity

Alias_namesguanine nucleotide binding protein-like 3 (nucleolar)
Alias_symbol (synonym)C77032
E2IG3
MGC800
NS
Other aliasNNP47
HGNC (Hugo) GNL3
LocusID (NCBI) 26354
Atlas_Id 41584
Location 3p21.1  [Link to chromosome band 3p21]
Location_base_pair Starts at 52719936 and ends at 52728510 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
GNL3 (3p21.1) / ARHGAP9 (12q13.3)GNL3 (3p21.1) / COL3A1 (2q32.2)GNL3 (3p21.1) / GNL3 (3p21.1)
GNL3 (3p21.1) / PI4KA (22q11.21)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GNL3   29931
Cards
Entrez_Gene (NCBI)GNL3  26354  G protein nucleolar 3
AliasesC77032; E2IG3; NNP47; NS
GeneCards (Weizmann)GNL3
Ensembl hg19 (Hinxton)ENSG00000163938 [Gene_View]  chr3:52719936-52728510 [Contig_View]  GNL3 [Vega]
Ensembl hg38 (Hinxton)ENSG00000163938 [Gene_View]  chr3:52719936-52728510 [Contig_View]  GNL3 [Vega]
ICGC DataPortalENSG00000163938
TCGA cBioPortalGNL3
AceView (NCBI)GNL3
Genatlas (Paris)GNL3
WikiGenes26354
SOURCE (Princeton)GNL3
Genetics Home Reference (NIH)GNL3
Genomic and cartography
GoldenPath hg19 (UCSC)GNL3  -     chr3:52719936-52728510 +  3p21.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)GNL3  -     3p21.1   [Description]    (hg38-Dec_2013)
EnsemblGNL3 - 3p21.1 [CytoView hg19]  GNL3 - 3p21.1 [CytoView hg38]
Mapping of homologs : NCBIGNL3 [Mapview hg19]  GNL3 [Mapview hg38]
OMIM608011   
Gene and transcription
Genbank (Entrez)AF191018 AI028402 AK027514 AK027516 AK315484
RefSeq transcript (Entrez)NM_014366 NM_206825 NM_206826
RefSeq genomic (Entrez)NC_000003 NC_018914 NG_027871 NT_022517 NW_004929309
Consensus coding sequences : CCDS (NCBI)GNL3
Cluster EST : UnigeneHs.313544 [ NCBI ]
CGAP (NCI)Hs.313544
Alternative Splicing GalleryENSG00000163938
Gene ExpressionGNL3 [ NCBI-GEO ]   GNL3 [ EBI - ARRAY_EXPRESS ]   GNL3 [ SEEK ]   GNL3 [ MEM ]
Gene Expression Viewer (FireBrowse)GNL3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)26354
GTEX Portal (Tissue expression)GNL3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BVP2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BVP2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BVP2
Splice isoforms : SwissVarQ9BVP2
PhosPhoSitePlusQ9BVP2
Domaine pattern : Prosite (Expaxy)G_CP (PS51721)   
Domains : Interpro (EBI)G_CP_dom    Gnl3_N_dom    GTP_binding_domain    P-loop_NTPase   
Domain families : Pfam (Sanger)GN3L_Grn1 (PF08701)    MMR_HSR1 (PF01926)   
Domain families : Pfam (NCBI)pfam08701    pfam01926   
Conserved Domain (NCBI)GNL3
DMDM Disease mutations26354
Blocks (Seattle)GNL3
SuperfamilyQ9BVP2
Human Protein AtlasENSG00000163938
Peptide AtlasQ9BVP2
HPRD06419
IPIIPI00306380   IPI00003886   IPI00798037   IPI00945015   IPI00946884   
Protein Interaction databases
DIP (DOE-UCLA)Q9BVP2
IntAct (EBI)Q9BVP2
FunCoupENSG00000163938
BioGRIDGNL3
STRING (EMBL)GNL3
ZODIACGNL3
Ontologies - Pathways
QuickGOQ9BVP2
Ontology : AmiGOGTPase activity  protein binding  GTP binding  extracellular space  nucleus  nucleoplasm  nucleolus  nucleolus  cell proliferation  membrane  positive regulation of telomere maintenance  positive regulation of protein sumoylation  regulation of cell proliferation  ribosome biogenesis  poly(A) RNA binding  positive regulation of pri-miRNA transcription from RNA polymerase II promoter  positive regulation of protein localization to chromosome, telomeric region  
Ontology : EGO-EBIGTPase activity  protein binding  GTP binding  extracellular space  nucleus  nucleoplasm  nucleolus  nucleolus  cell proliferation  membrane  positive regulation of telomere maintenance  positive regulation of protein sumoylation  regulation of cell proliferation  ribosome biogenesis  poly(A) RNA binding  positive regulation of pri-miRNA transcription from RNA polymerase II promoter  positive regulation of protein localization to chromosome, telomeric region  
Pathways : KEGGRibosome biogenesis in eukaryotes   
NDEx NetworkGNL3
Atlas of Cancer Signalling NetworkGNL3
Wikipedia pathwaysGNL3
Orthology - Evolution
OrthoDB26354
GeneTree (enSembl)ENSG00000163938
Phylogenetic Trees/Animal Genes : TreeFamGNL3
HOVERGENQ9BVP2
HOGENOMQ9BVP2
Homologs : HomoloGeneGNL3
Homology/Alignments : Family Browser (UCSC)GNL3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGNL3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GNL3
dbVarGNL3
ClinVarGNL3
1000_GenomesGNL3 
Exome Variant ServerGNL3
ExAC (Exome Aggregation Consortium)GNL3 (select the gene name)
Genetic variants : HAPMAP26354
Genomic Variants (DGV)GNL3 [DGVbeta]
DECIPHER (Syndromes)3:52719936-52728510  ENSG00000163938
CONAN: Copy Number AnalysisGNL3 
Mutations
ICGC Data PortalGNL3 
TCGA Data PortalGNL3 
Broad Tumor PortalGNL3
OASIS PortalGNL3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGNL3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGNL3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GNL3
DgiDB (Drug Gene Interaction Database)GNL3
DoCM (Curated mutations)GNL3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GNL3 (select a term)
intoGenGNL3
Cancer3DGNL3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608011   
Orphanet
MedgenGNL3
Genetic Testing Registry GNL3
NextProtQ9BVP2 [Medical]
TSGene26354
GENETestsGNL3
Huge Navigator GNL3 [HugePedia]
snp3D : Map Gene to Disease26354
BioCentury BCIQGNL3
ClinGenGNL3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD26354
Chemical/Pharm GKB GenePA134952132
Clinical trialGNL3
Miscellaneous
canSAR (ICR)GNL3 (select the gene name)
Probes
Litterature
PubMed100 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGNL3
EVEXGNL3
GoPubMedGNL3
iHOPGNL3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 13:07:47 CET 2017

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