Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

GNMT (glycine N-methyltransferase)

Identity

Other namesHEL-S-182mP
HGNC (Hugo) GNMT
LocusID (NCBI) 27232
Atlas_Id 45999
Location 6p21.1  [Link to chromosome band 6p21]
Location_base_pair Starts at 42928492 and ends at 42931618 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
TRERF1 (6p21.1) / GNMT (6p21.1)TRERF1 6p21.1 / GNMT 6p21.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GNMT   4415
Cards
Entrez_Gene (NCBI)GNMT  27232  glycine N-methyltransferase
AliasesHEL-S-182mP
GeneCards (Weizmann)GNMT
Ensembl hg19 (Hinxton)ENSG00000124713 [Gene_View]  chr6:42928492-42931618 [Contig_View]  GNMT [Vega]
Ensembl hg38 (Hinxton)ENSG00000124713 [Gene_View]  chr6:42928492-42931618 [Contig_View]  GNMT [Vega]
ICGC DataPortalENSG00000124713
TCGA cBioPortalGNMT
AceView (NCBI)GNMT
Genatlas (Paris)GNMT
WikiGenes27232
SOURCE (Princeton)GNMT
Genomic and cartography
GoldenPath hg19 (UCSC)GNMT  -     chr6:42928492-42931618 +  6p21.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)GNMT  -     6p21.1   [Description]    (hg38-Dec_2013)
EnsemblGNMT - 6p21.1 [CytoView hg19]  GNMT - 6p21.1 [CytoView hg38]
Mapping of homologs : NCBIGNMT [Mapview hg19]  GNMT [Mapview hg38]
OMIM606628   606664   
Gene and transcription
Genbank (Entrez)AF101477 BC032627 DQ890819 DQ893974 FJ224320
RefSeq transcript (Entrez)NM_001318865 NM_018960
RefSeq genomic (Entrez)NC_000006 NC_018917 NG_008396 NT_007592 NW_004929326
Consensus coding sequences : CCDS (NCBI)GNMT
Cluster EST : UnigeneHs.144914 [ NCBI ]
CGAP (NCI)Hs.144914
Alternative Splicing GalleryENSG00000124713
Gene ExpressionGNMT [ NCBI-GEO ]   GNMT [ EBI - ARRAY_EXPRESS ]   GNMT [ SEEK ]   GNMT [ MEM ]
Gene Expression Viewer (FireBrowse)GNMT [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)27232
GTEX Portal (Tissue expression)GNMT
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14749 (Uniprot)
NextProtQ14749  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ14749
Splice isoforms : SwissVarQ14749 (Swissvar)
PhosPhoSitePlusQ14749
Domaine pattern : Prosite (Expaxy)SAM_GNMT (PS51600)   
Domains : Interpro (EBI)Gly/Sar_N_MeTrfase    SAM-dependent_MTases   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
DMDM Disease mutations27232
Blocks (Seattle)GNMT
PDB (SRS)1R74    2AZT   
PDB (PDBSum)1R74    2AZT   
PDB (IMB)1R74    2AZT   
PDB (RSDB)1R74    2AZT   
Structural Biology KnowledgeBase1R74    2AZT   
SCOP (Structural Classification of Proteins)1R74    2AZT   
CATH (Classification of proteins structures)1R74    2AZT   
SuperfamilyQ14749
Human Protein AtlasENSG00000124713
Peptide AtlasQ14749
HPRD05970
IPIIPI00215925   
Protein Interaction databases
DIP (DOE-UCLA)Q14749
IntAct (EBI)Q14749
FunCoupENSG00000124713
BioGRIDGNMT
STRING (EMBL)GNMT
ZODIACGNMT
Ontologies - Pathways
QuickGOQ14749
Ontology : AmiGOprotein binding  folic acid binding  cytoplasm  cytosol  glycogen metabolic process  regulation of gluconeogenesis  cellular protein modification process  methionine metabolic process  one-carbon metabolic process  glycine binding  glycine N-methyltransferase activity  glycine N-methyltransferase activity  methylation  glyoxylate metabolic process  S-adenosylmethionine metabolic process  protein homotetramerization  
Ontology : EGO-EBIprotein binding  folic acid binding  cytoplasm  cytosol  glycogen metabolic process  regulation of gluconeogenesis  cellular protein modification process  methionine metabolic process  one-carbon metabolic process  glycine binding  glycine N-methyltransferase activity  glycine N-methyltransferase activity  methylation  glyoxylate metabolic process  S-adenosylmethionine metabolic process  protein homotetramerization  
Pathways : KEGGGlycine, serine and threonine metabolism   
NDEx NetworkGNMT
Atlas of Cancer Signalling NetworkGNMT
Wikipedia pathwaysGNMT
Orthology - Evolution
OrthoDB27232
GeneTree (enSembl)ENSG00000124713
Phylogenetic Trees/Animal Genes : TreeFamGNMT
Homologs : HomoloGeneGNMT
Homology/Alignments : Family Browser (UCSC)GNMT
Gene fusions - Rearrangements
Fusion: TCGATRERF1 6p21.1 GNMT 6p21.1 LUAD
Polymorphisms : SNP, variants
NCBI Variation ViewerGNMT [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GNMT
dbVarGNMT
ClinVarGNMT
1000_GenomesGNMT 
Exome Variant ServerGNMT
ExAC (Exome Aggregation Consortium)GNMT (select the gene name)
Genetic variants : HAPMAP27232
Genomic Variants (DGV)GNMT [DGVbeta]
Mutations
ICGC Data PortalGNMT 
TCGA Data PortalGNMT 
Broad Tumor PortalGNMT
OASIS PortalGNMT [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGNMT 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GNMT
DgiDB (Drug Gene Interaction Database)GNMT
DoCM (Curated mutations)GNMT (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GNMT (select a term)
intoGenGNMT
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)6:42928492-42931618  ENSG00000124713
CONAN: Copy Number AnalysisGNMT 
Mutations and Diseases : HGMDGNMT
OMIM606628    606664   
MedgenGNMT
Genetic Testing Registry GNMT
NextProtQ14749 [Medical]
TSGene27232
GENETestsGNMT
Huge Navigator GNMT [HugePedia]
snp3D : Map Gene to Disease27232
BioCentury BCIQGNMT
ClinGenGNMT
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD27232
Chemical/Pharm GKB GenePA28794
Clinical trialGNMT
Miscellaneous
canSAR (ICR)GNMT (select the gene name)
Probes
Litterature
PubMed46 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGNMT
EVEXGNMT
GoPubMedGNMT
iHOPGNMT
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 19 18:51:17 CEST 2016

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.