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GNMT (glycine N-methyltransferase)

Identity

Other names-
HGNC (Hugo) GNMT
LocusID (NCBI) 27232
Location 6p21.1
Location_base_pair Starts at 42928500 and ends at 42931618 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)GNMT   4415
Cards
Entrez_Gene (NCBI)GNMT  27232  glycine N-methyltransferase
GeneCards (Weizmann)GNMT
Ensembl (Hinxton)ENSG00000124713 [Gene_View]  chr6:42928500-42931618 [Contig_View]  GNMT [Vega]
ICGC DataPortalENSG00000124713
cBioPortalGNMT
AceView (NCBI)GNMT
Genatlas (Paris)GNMT
WikiGenes27232
SOURCE (Princeton)NM_018960
Genomic and cartography
GoldenPath (UCSC)GNMT  -  6p21.1   chr6:42928500-42931618 +  6p21.1   [Description]    (hg19-Feb_2009)
EnsemblGNMT - 6p21.1 [CytoView]
Mapping of homologs : NCBIGNMT [Mapview]
OMIM606628   606664   
Gene and transcription
Genbank (Entrez)AF101477 BC032627 DQ890819 DQ893974 FJ224320
RefSeq transcript (Entrez)NM_018960
RefSeq genomic (Entrez)AC_000138 NC_000006 NC_018917 NG_008396 NT_007592 NW_001838981 NW_004929326
Consensus coding sequences : CCDS (NCBI)GNMT
Cluster EST : UnigeneHs.144914 [ NCBI ]
CGAP (NCI)Hs.144914
Alternative Splicing : Fast-db (Paris)GSHG0025740
Alternative Splicing GalleryENSG00000124713
Gene ExpressionGNMT [ NCBI-GEO ]     GNMT [ SEEK ]   GNMT [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14749 (Uniprot)
NextProtQ14749  [Medical]
With graphics : InterProQ14749
Splice isoforms : SwissVarQ14749 (Swissvar)
Domaine pattern : Prosite (Expaxy)SAM_GNMT (PS51600)   
Domains : Interpro (EBI)Gly/Sar_N_MeTrfase [organisation]   SAM-dependent_MTases-like [organisation]  
Related proteins : CluSTrQ14749
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
DMDM Disease mutations27232
Blocks (Seattle)Q14749
PDB (SRS)1R74    2AZT   
PDB (PDBSum)1R74    2AZT   
PDB (IMB)1R74    2AZT   
PDB (RSDB)1R74    2AZT   
Human Protein AtlasENSG00000124713 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasQ14749
HPRD05970
IPIIPI00215925   
Protein Interaction databases
DIP (DOE-UCLA)Q14749
IntAct (EBI)Q14749
FunCoupENSG00000124713
BioGRIDGNMT
InParanoidQ14749
Interologous Interaction database Q14749
IntegromeDBGNMT
STRING (EMBL)GNMT
Ontologies - Pathways
Ontology : AmiGOprotein binding  folic acid binding  cytoplasm  glycogen metabolic process  regulation of gluconeogenesis  cellular protein modification process  methionine metabolic process  one-carbon metabolic process  glycine binding  glycine N-methyltransferase activity  methylation  S-adenosylmethionine metabolic process  protein homotetramerization  
Ontology : EGO-EBIprotein binding  folic acid binding  cytoplasm  glycogen metabolic process  regulation of gluconeogenesis  cellular protein modification process  methionine metabolic process  one-carbon metabolic process  glycine binding  glycine N-methyltransferase activity  methylation  S-adenosylmethionine metabolic process  protein homotetramerization  
Pathways : KEGGGlycine, serine and threonine metabolism   
Protein Interaction DatabaseGNMT
Wikipedia pathwaysGNMT
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)GNMT
snp3D : Map Gene to Disease27232
SNP (GeneSNP Utah)GNMT
SNP : HGBaseGNMT
Genetic variants : HAPMAPGNMT
Exome VariantGNMT
1000_GenomesGNMT 
ICGC programENSG00000124713 
Somatic Mutations in Cancer : COSMICGNMT 
CONAN: Copy Number AnalysisGNMT 
Mutations and Diseases : HGMDGNMT
Genomic VariantsGNMT  GNMT [DGVbeta]
dbVarGNMT
ClinVarGNMT
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM606628    606664   
MedgenGNMT
GENETestsGNMT
Disease Genetic AssociationGNMT
Huge Navigator GNMT [HugePedia]  GNMT [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneGNMT
Homology/Alignments : Family Browser (UCSC)GNMT
Phylogenetic Trees/Animal Genes : TreeFamGNMT
Chemical/Protein Interactions : CTD27232
Chemical/Pharm GKB GenePA28794
Clinical trialGNMT
Cancer Resource (Charite)ENSG00000124713
Other databases
Probes
Litterature
PubMed38 Pubmed reference(s) in Entrez
CoreMineGNMT
iHOPGNMT
OncoSearchGNMT
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jul 30 13:56:37 CEST 2014

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