Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

GNPAT (glyceronephosphate O-acyltransferase)

Identity

Alias_symbol (synonym)DHAPAT
DAPAT
DAP-AT
Other aliasRCDP2
HGNC (Hugo) GNPAT
LocusID (NCBI) 8443
Atlas_Id 63864
Location 1q42.2  [Link to chromosome band 1q42]
Location_base_pair Starts at 231241173 and ends at 231277973 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ARID4B (1q42.3) / GNPAT (1q42.2)GNPAT (1q42.2) / GNPAT (1q42.2)GNPAT (1q42.2) / PCNX2 (1q42.2)
GNPAT (1q42.2) / TRIM67 (1q42.2)NFIA (1p31.3) / GNPAT (1q42.2)PLP1 (Xq22.2) / GNPAT (1q42.2)
GNPAT TRIM67GNPAT PCNXL2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GNPAT   4416
Cards
Entrez_Gene (NCBI)GNPAT  8443  glyceronephosphate O-acyltransferase
AliasesDAP-AT; DAPAT; DHAPAT; RCDP2
GeneCards (Weizmann)GNPAT
Ensembl hg19 (Hinxton)ENSG00000116906 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000116906 [Gene_View]  chr1:231241173-231277973 [Contig_View]  GNPAT [Vega]
ICGC DataPortalENSG00000116906
TCGA cBioPortalGNPAT
AceView (NCBI)GNPAT
Genatlas (Paris)GNPAT
WikiGenes8443
SOURCE (Princeton)GNPAT
Genetics Home Reference (NIH)GNPAT
Genomic and cartography
GoldenPath hg38 (UCSC)GNPAT  -     chr1:231241173-231277973 +  1q42.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GNPAT  -     1q42.2   [Description]    (hg19-Feb_2009)
EnsemblGNPAT - 1q42.2 [CytoView hg19]  GNPAT - 1q42.2 [CytoView hg38]
Mapping of homologs : NCBIGNPAT [Mapview hg19]  GNPAT [Mapview hg38]
OMIM222765   602744   
Gene and transcription
Genbank (Entrez)AB209882 AF035285 AF043937 AJ002190 AK222773
RefSeq transcript (Entrez)NM_001316350 NM_014236
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GNPAT
Cluster EST : UnigeneHs.498028 [ NCBI ]
CGAP (NCI)Hs.498028
Alternative Splicing GalleryENSG00000116906
Gene ExpressionGNPAT [ NCBI-GEO ]   GNPAT [ EBI - ARRAY_EXPRESS ]   GNPAT [ SEEK ]   GNPAT [ MEM ]
Gene Expression Viewer (FireBrowse)GNPAT [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8443
GTEX Portal (Tissue expression)GNPAT
Protein : pattern, domain, 3D structure
UniProt/SwissProtO15228   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO15228  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO15228
Splice isoforms : SwissVarO15228
Catalytic activity : Enzyme2.3.1.42 [ Enzyme-Expasy ]   2.3.1.422.3.1.42 [ IntEnz-EBI ]   2.3.1.42 [ BRENDA ]   2.3.1.42 [ KEGG ]   
PhosPhoSitePlusO15228
Domains : Interpro (EBI)DHAPAT    GPAT/DHAPAT    Plipid/glycerol_acylTrfase   
Domain families : Pfam (Sanger)Acyltransferase (PF01553)   
Domain families : Pfam (NCBI)pfam01553   
Domain families : Smart (EMBL)PlsC (SM00563)  
Conserved Domain (NCBI)GNPAT
DMDM Disease mutations8443
Blocks (Seattle)GNPAT
SuperfamilyO15228
Human Protein AtlasENSG00000116906
Peptide AtlasO15228
HPRD04120
IPIIPI00005677   IPI00514057   IPI00640892   
Protein Interaction databases
DIP (DOE-UCLA)O15228
IntAct (EBI)O15228
FunCoupENSG00000116906
BioGRIDGNPAT
STRING (EMBL)GNPAT
ZODIACGNPAT
Ontologies - Pathways
QuickGOO15228
Ontology : AmiGOreceptor binding  mitochondrion  peroxisome  peroxisome  peroxisomal membrane  peroxisomal membrane  peroxisomal matrix  phosphatidic acid biosynthetic process  synapse assembly  response to nutrient  ether lipid biosynthetic process  ether lipid biosynthetic process  membrane  glycerone-phosphate O-acyltransferase activity  glycerone-phosphate O-acyltransferase activity  palmitoyl-CoA hydrolase activity  cerebellum morphogenesis  paranodal junction assembly  response to drug  response to starvation  membrane organization  response to fatty acid  
Ontology : EGO-EBIreceptor binding  mitochondrion  peroxisome  peroxisome  peroxisomal membrane  peroxisomal membrane  peroxisomal matrix  phosphatidic acid biosynthetic process  synapse assembly  response to nutrient  ether lipid biosynthetic process  ether lipid biosynthetic process  membrane  glycerone-phosphate O-acyltransferase activity  glycerone-phosphate O-acyltransferase activity  palmitoyl-CoA hydrolase activity  cerebellum morphogenesis  paranodal junction assembly  response to drug  response to starvation  membrane organization  response to fatty acid  
Pathways : KEGGGlycerophospholipid metabolism    Peroxisome   
NDEx NetworkGNPAT
Atlas of Cancer Signalling NetworkGNPAT
Wikipedia pathwaysGNPAT
Orthology - Evolution
OrthoDB8443
GeneTree (enSembl)ENSG00000116906
Phylogenetic Trees/Animal Genes : TreeFamGNPAT
HOVERGENO15228
HOGENOMO15228
Homologs : HomoloGeneGNPAT
Homology/Alignments : Family Browser (UCSC)GNPAT
Gene fusions - Rearrangements
Fusion: TCGAGNPAT TRIM67
Fusion: TCGAGNPAT PCNXL2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGNPAT [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GNPAT
dbVarGNPAT
ClinVarGNPAT
1000_GenomesGNPAT 
Exome Variant ServerGNPAT
ExAC (Exome Aggregation Consortium)GNPAT (select the gene name)
Genetic variants : HAPMAP8443
Genomic Variants (DGV)GNPAT [DGVbeta]
DECIPHERGNPAT [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGNPAT 
Mutations
ICGC Data PortalGNPAT 
TCGA Data PortalGNPAT 
Broad Tumor PortalGNPAT
OASIS PortalGNPAT [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGNPAT  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGNPAT
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Mendelian genes
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch GNPAT
DgiDB (Drug Gene Interaction Database)GNPAT
DoCM (Curated mutations)GNPAT (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GNPAT (select a term)
intoGenGNPAT
Cancer3DGNPAT(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM222765    602744   
Orphanet21389   
MedgenGNPAT
Genetic Testing Registry GNPAT
NextProtO15228 [Medical]
TSGene8443
GENETestsGNPAT
Target ValidationGNPAT
Huge Navigator GNPAT [HugePedia]
snp3D : Map Gene to Disease8443
BioCentury BCIQGNPAT
ClinGenGNPAT
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8443
Chemical/Pharm GKB GenePA28795
Clinical trialGNPAT
Miscellaneous
canSAR (ICR)GNPAT (select the gene name)
Probes
Litterature
PubMed36 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGNPAT
EVEXGNPAT
GoPubMedGNPAT
iHOPGNPAT
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 15:50:52 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.