Atlas of Genetics and Cytogenetics in Oncology and Haematology


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GNPDA1 (glucosamine-6-phosphate deaminase 1)

Identity

Alias_namesGNPI
glucosamine-6-phosphate isomerase
Alias_symbol (synonym)GNPDA
HLN
GPI
KIAA0060
Other aliasGNP1
HGNC (Hugo) GNPDA1
LocusID (NCBI) 10007
Atlas_Id 63865
Location 5q31.3  [Link to chromosome band 5q31]
Location_base_pair Starts at 142000669 and ends at 142013055 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
GNPDA1 (5q31.3) / GNPDA1 (5q31.3)GNPDA1 (5q31.3) / PPP2R2B (5q32)GNPDA1 (5q31.3) / RNGTT (6q15)
KLHL10 (17q21.2) / GNPDA1 (5q31.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GNPDA1   4417
Cards
Entrez_Gene (NCBI)GNPDA1  10007  glucosamine-6-phosphate deaminase 1
AliasesGNP1; GNPDA; GNPI; GPI; 
HLN
GeneCards (Weizmann)GNPDA1
Ensembl hg19 (Hinxton)ENSG00000113552 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000113552 [Gene_View]  chr5:142000669-142013055 [Contig_View]  GNPDA1 [Vega]
ICGC DataPortalENSG00000113552
TCGA cBioPortalGNPDA1
AceView (NCBI)GNPDA1
Genatlas (Paris)GNPDA1
WikiGenes10007
SOURCE (Princeton)GNPDA1
Genetics Home Reference (NIH)GNPDA1
Genomic and cartography
GoldenPath hg38 (UCSC)GNPDA1  -     chr5:142000669-142013055 -  5q31.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GNPDA1  -     5q31.3   [Description]    (hg19-Feb_2009)
EnsemblGNPDA1 - 5q31.3 [CytoView hg19]  GNPDA1 - 5q31.3 [CytoView hg38]
Mapping of homologs : NCBIGNPDA1 [Mapview hg19]  GNPDA1 [Mapview hg38]
OMIM601798   
Gene and transcription
Genbank (Entrez)AF029914 AF048826 AJ002231 AK022779 AK290686
RefSeq transcript (Entrez)NM_005471
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GNPDA1
Cluster EST : UnigeneHs.633853 [ NCBI ]
CGAP (NCI)Hs.633853
Alternative Splicing GalleryENSG00000113552
Gene ExpressionGNPDA1 [ NCBI-GEO ]   GNPDA1 [ EBI - ARRAY_EXPRESS ]   GNPDA1 [ SEEK ]   GNPDA1 [ MEM ]
Gene Expression Viewer (FireBrowse)GNPDA1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10007
GTEX Portal (Tissue expression)GNPDA1
Human Protein AtlasENSG00000113552-GNPDA1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP46926   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP46926  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP46926
Splice isoforms : SwissVarP46926
Catalytic activity : Enzyme3.5.99.6 [ Enzyme-Expasy ]   3.5.99.63.5.99.6 [ IntEnz-EBI ]   3.5.99.6 [ BRENDA ]   3.5.99.6 [ KEGG ]   
PhosPhoSitePlusP46926
Domaine pattern : Prosite (Expaxy)GLC_GALNAC_ISOMERASE (PS01161)   
Domains : Interpro (EBI)Glc/Gal-6P_isomerase    Glucosamine6P_isomerase    Glucosamine6P_isomerase_CS   
Domain families : Pfam (Sanger)Glucosamine_iso (PF01182)   
Domain families : Pfam (NCBI)pfam01182   
Conserved Domain (NCBI)GNPDA1
DMDM Disease mutations10007
Blocks (Seattle)GNPDA1
PDB (SRS)1NE7   
PDB (PDBSum)1NE7   
PDB (IMB)1NE7   
PDB (RSDB)1NE7   
Structural Biology KnowledgeBase1NE7   
SCOP (Structural Classification of Proteins)1NE7   
CATH (Classification of proteins structures)1NE7   
SuperfamilyP46926
Human Protein Atlas [tissue]ENSG00000113552-GNPDA1 [tissue]
Peptide AtlasP46926
HPRD09048
IPIIPI00009305   IPI00903190   IPI00922562   IPI00967567   IPI00965994   IPI00963908   IPI00963913   IPI00967259   
Protein Interaction databases
DIP (DOE-UCLA)P46926
IntAct (EBI)P46926
FunCoupENSG00000113552
BioGRIDGNPDA1
STRING (EMBL)GNPDA1
ZODIACGNPDA1
Ontologies - Pathways
QuickGOP46926
Ontology : AmiGOglucosamine-6-phosphate deaminase activity  glucosamine-6-phosphate deaminase activity  protein binding  cytoplasm  cytosol  glucose metabolic process  glucosamine catabolic process  N-acetylglucosamine metabolic process  generation of precursor metabolites and energy  single fertilization  hydrolase activity  extracellular exosome  
Ontology : EGO-EBIglucosamine-6-phosphate deaminase activity  glucosamine-6-phosphate deaminase activity  protein binding  cytoplasm  cytosol  glucose metabolic process  glucosamine catabolic process  N-acetylglucosamine metabolic process  generation of precursor metabolites and energy  single fertilization  hydrolase activity  extracellular exosome  
Pathways : KEGGAmino sugar and nucleotide sugar metabolism   
NDEx NetworkGNPDA1
Atlas of Cancer Signalling NetworkGNPDA1
Wikipedia pathwaysGNPDA1
Orthology - Evolution
OrthoDB10007
GeneTree (enSembl)ENSG00000113552
Phylogenetic Trees/Animal Genes : TreeFamGNPDA1
HOVERGENP46926
HOGENOMP46926
Homologs : HomoloGeneGNPDA1
Homology/Alignments : Family Browser (UCSC)GNPDA1
Gene fusions - Rearrangements
Fusion: Tumor Portal GNPDA1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGNPDA1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GNPDA1
dbVarGNPDA1
ClinVarGNPDA1
1000_GenomesGNPDA1 
Exome Variant ServerGNPDA1
ExAC (Exome Aggregation Consortium)ENSG00000113552
GNOMAD BrowserENSG00000113552
Genetic variants : HAPMAP10007
Genomic Variants (DGV)GNPDA1 [DGVbeta]
DECIPHERGNPDA1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGNPDA1 
Mutations
ICGC Data PortalGNPDA1 
TCGA Data PortalGNPDA1 
Broad Tumor PortalGNPDA1
OASIS PortalGNPDA1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGNPDA1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGNPDA1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GNPDA1
DgiDB (Drug Gene Interaction Database)GNPDA1
DoCM (Curated mutations)GNPDA1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GNPDA1 (select a term)
intoGenGNPDA1
Cancer3DGNPDA1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601798   
Orphanet
MedgenGNPDA1
Genetic Testing Registry GNPDA1
NextProtP46926 [Medical]
TSGene10007
GENETestsGNPDA1
Target ValidationGNPDA1
Huge Navigator GNPDA1 [HugePedia]
snp3D : Map Gene to Disease10007
BioCentury BCIQGNPDA1
ClinGenGNPDA1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10007
Chemical/Pharm GKB GenePA28796
Clinical trialGNPDA1
Miscellaneous
canSAR (ICR)GNPDA1 (select the gene name)
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGNPDA1
EVEXGNPDA1
GoPubMedGNPDA1
iHOPGNPDA1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Nov 9 11:49:14 CET 2017

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