GOLGA1 (golgin A1)

2016-10-01  

Identity

HGNC
GOLGA1
LOCATION
9q33.3
LOCUSID
2800
ALIAS
golgin-97
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 2800
MIM: 602502
HGNC: 4424
Ensembl: ENSG00000136935

Variants:

dbSNP: 2800
ClinVar: 2800
TCGA: ENSG00000136935
COSMIC: GOLGA1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000136935ENST00000373555Q92805
ENSG00000136935ENST00000421514Q5T165
ENSG00000136935ENST00000475407R4GNH1
ENSG00000136935ENST00000485337H0YE54

Expression (GTEx)

0
5
10
15
20
25
30
35
40
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
Intra-Golgi and retrograde Golgi-to-ER trafficREACTOMER-HSA-6811442
Retrograde transport at the Trans-Golgi-NetworkREACTOMER-HSA-6811440

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
152692792004Autoantigen Golgin-97, an effector of Arl1 GTPase, participates in traffic from the endosome to the trans-golgi network.66
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
162627252005E-cadherin transport from the trans-Golgi network in tubulovesicular carriers is selectively regulated by golgin-97.36
206106572010FIP1/RCP binding to Golgin-97 regulates retrograde transport from recycling endosomes to the trans-Golgi network.16
156547692005The trans-Golgi network GRIP-domain proteins form alpha-helical homodimers.11
205831702010Follow-up association studies of chromosome region 9q and nonsyndromic cleft lip/palate.8
172764772007A host cell membrane protein, golgin-97, is essential for poxvirus morphogenesis.6

Citation

Dessen P

GOLGA1 (golgin A1)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56536/golga1