GOLM1 (golgi membrane protein 1)

2007-12-01  

Identity

HGNC
GOLM1
LOCATION
9q21.33
LOCUSID
51280
ALIAS
C9orf155,GOLPH2,GP73,HEL46,PSEC0257,bA379P1.3
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 51280
MIM: 606804
HGNC: 15451
Ensembl: ENSG00000135052

Variants:

dbSNP: 51280
ClinVar: 51280
TCGA: ENSG00000135052
COSMIC: GOLM1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000135052ENST00000388711Q8NBJ4
ENSG00000135052ENST00000388711B3KNK9
ENSG00000135052ENST00000388712Q8NBJ4
ENSG00000135052ENST00000388712B3KNK9
ENSG00000135052ENST00000466178C9J941
ENSG00000135052ENST00000470762F8WAT9
ENSG00000135052ENST00000486130C9JYM4

Expression (GTEx)

0
50
100
150
200
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
179984372008Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease.189
120296282002Expression of GP73, a resident Golgi membrane protein, in viral and nonviral liver disease.65
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
251153962014The microRNA-23b/27b/24-1 cluster is a disease progression marker and tumor suppressor in prostate cancer.50
242843622014The tumor-suppressive microRNA-143/145 cluster inhibits cell migration and invasion by targeting GOLM1 in prostate cancer.45
273765742016Inter-individual variability and genetic influences on cytokine responses to bacteria and fungi.45
187811512008GOLPH2 protein expression as a novel tissue biomarker for prostate cancer: implications for tissue-based diagnostics.42
176620252007Endosomal trafficking and proprotein convertase cleavage of cis Golgi protein GP73 produces marker for hepatocellular carcinoma.35
192917862009Golgi phosphoprotein 2 (GOLPH2) expression in liver tumors and its value as a serum marker in hepatocellular carcinomas.34
275695822016GOLM1 Modulates EGFR/RTK Cell-Surface Recycling to Drive Hepatocellular Carcinoma Metastasis.34

Citation

Dessen P

GOLM1 (golgi membrane protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-12-01

Online version: http://atlasgeneticsoncology.org/gene/49952/golm1