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GOLPH3 (golgi phosphoprotein 3)

Identity

Alias_namesgolgi phosphoprotein 3 (coat-protein)
Alias_symbol (synonym)GPP34
GOPP1
MIDAS
Vps74
Other alias
HGNC (Hugo) GOLPH3
LocusID (NCBI) 64083
Atlas_Id 51006
Location 5p13.3  [Link to chromosome band 5p13]
Location_base_pair Starts at 32124718 and ends at 32174319 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
GOLPH3 (5p13.3) / HNRNPC (14q11.2)GOLPH3 (5p13.3) / LRTM1 (3p14.3)GOLPH3 (5p13.3) / RAB11FIP1 (8p11.23)
PARN (16p13.12) / GOLPH3 (5p13.3)ROBO2 (3p12.3) / GOLPH3 (5p13.3)GOLPH3 5p13.3 / LRTM1 3p14.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GOLPH3   15452
Cards
Entrez_Gene (NCBI)GOLPH3  64083  golgi phosphoprotein 3
AliasesGOPP1; GPP34; MIDAS; Vps74
GeneCards (Weizmann)GOLPH3
Ensembl hg19 (Hinxton)ENSG00000113384 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000113384 [Gene_View]  chr5:32124718-32174319 [Contig_View]  GOLPH3 [Vega]
ICGC DataPortalENSG00000113384
TCGA cBioPortalGOLPH3
AceView (NCBI)GOLPH3
Genatlas (Paris)GOLPH3
WikiGenes64083
SOURCE (Princeton)GOLPH3
Genetics Home Reference (NIH)GOLPH3
Genomic and cartography
GoldenPath hg38 (UCSC)GOLPH3  -     chr5:32124718-32174319 -  5p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GOLPH3  -     5p13.3   [Description]    (hg19-Feb_2009)
EnsemblGOLPH3 - 5p13.3 [CytoView hg19]  GOLPH3 - 5p13.3 [CytoView hg38]
Mapping of homologs : NCBIGOLPH3 [Mapview hg19]  GOLPH3 [Mapview hg38]
OMIM612207   
Gene and transcription
Genbank (Entrez)AJ296152 AK057544 AK075077 AK075156 AK092604
RefSeq transcript (Entrez)NM_022130
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GOLPH3
Cluster EST : UnigeneHs.408909 [ NCBI ]
CGAP (NCI)Hs.408909
Alternative Splicing GalleryENSG00000113384
Gene ExpressionGOLPH3 [ NCBI-GEO ]   GOLPH3 [ EBI - ARRAY_EXPRESS ]   GOLPH3 [ SEEK ]   GOLPH3 [ MEM ]
Gene Expression Viewer (FireBrowse)GOLPH3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)64083
GTEX Portal (Tissue expression)GOLPH3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H4A6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H4A6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H4A6
Splice isoforms : SwissVarQ9H4A6
PhosPhoSitePlusQ9H4A6
Domains : Interpro (EBI)GPP34-like   
Domain families : Pfam (Sanger)GPP34 (PF05719)   
Domain families : Pfam (NCBI)pfam05719   
Conserved Domain (NCBI)GOLPH3
DMDM Disease mutations64083
Blocks (Seattle)GOLPH3
PDB (SRS)3KN1   
PDB (PDBSum)3KN1   
PDB (IMB)3KN1   
PDB (RSDB)3KN1   
Structural Biology KnowledgeBase3KN1   
SCOP (Structural Classification of Proteins)3KN1   
CATH (Classification of proteins structures)3KN1   
SuperfamilyQ9H4A6
Human Protein AtlasENSG00000113384
Peptide AtlasQ9H4A6
HPRD11007
IPIIPI00005490   IPI01010778   IPI00975873   IPI00965013   
Protein Interaction databases
DIP (DOE-UCLA)Q9H4A6
IntAct (EBI)Q9H4A6
FunCoupENSG00000113384
BioGRIDGOLPH3
STRING (EMBL)GOLPH3
ZODIACGOLPH3
Ontologies - Pathways
QuickGOQ9H4A6
Ontology : AmiGOprotein binding  mitochondrion  mitochondrial intermembrane space  endosome  Golgi apparatus  Golgi apparatus  trans-Golgi network  cytosol  plasma membrane  retrograde vesicle-mediated transport, Golgi to ER  Golgi organization  cell proliferation  glycoprotein biosynthetic process  protein secretion  gene expression  regulation of mitochondrion organization  cell migration  enzyme binding  lamellipodium assembly  Golgi cisterna  positive regulation of TOR signaling  Golgi cisterna membrane  Golgi to plasma membrane protein transport  negative regulation of apoptotic process  intracellular membrane-bounded organelle  protein retention in Golgi apparatus  Golgi vesicle budding  positive regulation of protein secretion  leukocyte tethering or rolling  cell adhesion molecule production  phosphatidylinositol-4-phosphate binding  Golgi ribbon formation  asymmetric Golgi ribbon formation  
Ontology : EGO-EBIprotein binding  mitochondrion  mitochondrial intermembrane space  endosome  Golgi apparatus  Golgi apparatus  trans-Golgi network  cytosol  plasma membrane  retrograde vesicle-mediated transport, Golgi to ER  Golgi organization  cell proliferation  glycoprotein biosynthetic process  protein secretion  gene expression  regulation of mitochondrion organization  cell migration  enzyme binding  lamellipodium assembly  Golgi cisterna  positive regulation of TOR signaling  Golgi cisterna membrane  Golgi to plasma membrane protein transport  negative regulation of apoptotic process  intracellular membrane-bounded organelle  protein retention in Golgi apparatus  Golgi vesicle budding  positive regulation of protein secretion  leukocyte tethering or rolling  cell adhesion molecule production  phosphatidylinositol-4-phosphate binding  Golgi ribbon formation  asymmetric Golgi ribbon formation  
Pathways : KEGGTranscriptional misregulation in cancer   
NDEx NetworkGOLPH3
Atlas of Cancer Signalling NetworkGOLPH3
Wikipedia pathwaysGOLPH3
Orthology - Evolution
OrthoDB64083
GeneTree (enSembl)ENSG00000113384
Phylogenetic Trees/Animal Genes : TreeFamGOLPH3
HOVERGENQ9H4A6
HOGENOMQ9H4A6
Homologs : HomoloGeneGOLPH3
Homology/Alignments : Family Browser (UCSC)GOLPH3
Gene fusions - Rearrangements
Fusion : MitelmanGOLPH3/LRTM1 [5p13.3/3p14.3]  
Fusion: TCGAGOLPH3 5p13.3 LRTM1 3p14.3 LUSC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGOLPH3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GOLPH3
dbVarGOLPH3
ClinVarGOLPH3
1000_GenomesGOLPH3 
Exome Variant ServerGOLPH3
ExAC (Exome Aggregation Consortium)GOLPH3 (select the gene name)
Genetic variants : HAPMAP64083
Genomic Variants (DGV)GOLPH3 [DGVbeta]
DECIPHERGOLPH3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGOLPH3 
Mutations
ICGC Data PortalGOLPH3 
TCGA Data PortalGOLPH3 
Broad Tumor PortalGOLPH3
OASIS PortalGOLPH3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGOLPH3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGOLPH3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GOLPH3
DgiDB (Drug Gene Interaction Database)GOLPH3
DoCM (Curated mutations)GOLPH3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GOLPH3 (select a term)
intoGenGOLPH3
Cancer3DGOLPH3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612207   
Orphanet
MedgenGOLPH3
Genetic Testing Registry GOLPH3
NextProtQ9H4A6 [Medical]
TSGene64083
GENETestsGOLPH3
Target ValidationGOLPH3
Huge Navigator GOLPH3 [HugePedia]
snp3D : Map Gene to Disease64083
BioCentury BCIQGOLPH3
ClinGenGOLPH3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD64083
Chemical/Pharm GKB GenePA28812
Clinical trialGOLPH3
Miscellaneous
canSAR (ICR)GOLPH3 (select the gene name)
Probes
Litterature
PubMed66 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGOLPH3
EVEXGOLPH3
GoPubMedGOLPH3
iHOPGOLPH3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:54:33 CEST 2017

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