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GOT1L1 (glutamic-oxaloacetic transaminase 1-like 1)

Identity

Alias_symbol (synonym)MGC33309
Other alias-
HGNC (Hugo) GOT1L1
LocusID (NCBI) 137362
Atlas_Id 63914
Location 8p11.23  [Link to chromosome band 8p11]
Location_base_pair Starts at 37934281 and ends at 37940129 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
KAT6A (8p11.21) / GOT1L1 (8p11.23)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GOT1L1   28487
Cards
Entrez_Gene (NCBI)GOT1L1  137362  glutamic-oxaloacetic transaminase 1-like 1
Aliases
GeneCards (Weizmann)GOT1L1
Ensembl hg19 (Hinxton)ENSG00000169154 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000169154 [Gene_View]  chr8:37934281-37940129 [Contig_View]  GOT1L1 [Vega]
ICGC DataPortalENSG00000169154
TCGA cBioPortalGOT1L1
AceView (NCBI)GOT1L1
Genatlas (Paris)GOT1L1
WikiGenes137362
SOURCE (Princeton)GOT1L1
Genetics Home Reference (NIH)GOT1L1
Genomic and cartography
GoldenPath hg38 (UCSC)GOT1L1  -     chr8:37934281-37940129 -  8p11.23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GOT1L1  -     8p11.23   [Description]    (hg19-Feb_2009)
EnsemblGOT1L1 - 8p11.23 [CytoView hg19]  GOT1L1 - 8p11.23 [CytoView hg38]
Mapping of homologs : NCBIGOT1L1 [Mapview hg19]  GOT1L1 [Mapview hg38]
Gene and transcription
Genbank (Entrez)BC029504 BM559469
RefSeq transcript (Entrez)NM_152413
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GOT1L1
Cluster EST : UnigeneHs.380740 [ NCBI ]
CGAP (NCI)Hs.380740
Alternative Splicing GalleryENSG00000169154
Gene ExpressionGOT1L1 [ NCBI-GEO ]   GOT1L1 [ EBI - ARRAY_EXPRESS ]   GOT1L1 [ SEEK ]   GOT1L1 [ MEM ]
Gene Expression Viewer (FireBrowse)GOT1L1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)137362
GTEX Portal (Tissue expression)GOT1L1
Human Protein AtlasENSG00000169154-GOT1L1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NHS2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NHS2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NHS2
Splice isoforms : SwissVarQ8NHS2
Catalytic activity : Enzyme2.6.1.- [ Enzyme-Expasy ]   2.6.1.-2.6.1.- [ IntEnz-EBI ]   2.6.1.- [ BRENDA ]   2.6.1.- [ KEGG ]   
PhosPhoSitePlusQ8NHS2
Domains : Interpro (EBI)Aminotransferase_I/II    Asp_trans    PyrdxlP-dep_Trfase    PyrdxlP-dep_Trfase_major_sub2   
Domain families : Pfam (Sanger)Aminotran_1_2 (PF00155)   
Domain families : Pfam (NCBI)pfam00155   
Conserved Domain (NCBI)GOT1L1
DMDM Disease mutations137362
Blocks (Seattle)GOT1L1
SuperfamilyQ8NHS2
Human Protein Atlas [tissue]ENSG00000169154-GOT1L1 [tissue]
Peptide AtlasQ8NHS2
HPRD14558
IPIIPI00169311   IPI00974528   IPI00974097   
Protein Interaction databases
DIP (DOE-UCLA)Q8NHS2
IntAct (EBI)Q8NHS2
FunCoupENSG00000169154
BioGRIDGOT1L1
STRING (EMBL)GOT1L1
ZODIACGOT1L1
Ontologies - Pathways
QuickGOQ8NHS2
Ontology : AmiGOL-aspartate:2-oxoglutarate aminotransferase activity  mitochondrion  cytosol  aspartate biosynthetic process  pyridoxal phosphate binding  
Ontology : EGO-EBIL-aspartate:2-oxoglutarate aminotransferase activity  mitochondrion  cytosol  aspartate biosynthetic process  pyridoxal phosphate binding  
NDEx NetworkGOT1L1
Atlas of Cancer Signalling NetworkGOT1L1
Wikipedia pathwaysGOT1L1
Orthology - Evolution
OrthoDB137362
GeneTree (enSembl)ENSG00000169154
Phylogenetic Trees/Animal Genes : TreeFamGOT1L1
HOVERGENQ8NHS2
HOGENOMQ8NHS2
Homologs : HomoloGeneGOT1L1
Homology/Alignments : Family Browser (UCSC)GOT1L1
Gene fusions - Rearrangements
Tumor Fusion PortalGOT1L1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGOT1L1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GOT1L1
dbVarGOT1L1
ClinVarGOT1L1
1000_GenomesGOT1L1 
Exome Variant ServerGOT1L1
ExAC (Exome Aggregation Consortium)ENSG00000169154
GNOMAD BrowserENSG00000169154
Genetic variants : HAPMAP137362
Genomic Variants (DGV)GOT1L1 [DGVbeta]
DECIPHERGOT1L1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGOT1L1 
Mutations
ICGC Data PortalGOT1L1 
TCGA Data PortalGOT1L1 
Broad Tumor PortalGOT1L1
OASIS PortalGOT1L1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGOT1L1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGOT1L1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GOT1L1
DgiDB (Drug Gene Interaction Database)GOT1L1
DoCM (Curated mutations)GOT1L1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GOT1L1 (select a term)
intoGenGOT1L1
Cancer3DGOT1L1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETGOT1L1
MedgenGOT1L1
Genetic Testing Registry GOT1L1
NextProtQ8NHS2 [Medical]
TSGene137362
GENETestsGOT1L1
Target ValidationGOT1L1
Huge Navigator GOT1L1 [HugePedia]
snp3D : Map Gene to Disease137362
BioCentury BCIQGOT1L1
ClinGenGOT1L1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD137362
Chemical/Pharm GKB GenePA142671724
Clinical trialGOT1L1
Miscellaneous
canSAR (ICR)GOT1L1 (select the gene name)
Probes
Litterature
PubMed5 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGOT1L1
EVEXGOT1L1
GoPubMedGOT1L1
iHOPGOT1L1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 13:18:13 CET 2017

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