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GP1BA (glycoprotein Ib platelet alpha subunit)

Identity

Alias_namesGP1B
glycoprotein Ib (platelet)
Alias_symbol (synonym)CD42b
GPIbalpha
Other aliasBDPLT1
BDPLT3
BSS
CD42B
CD42b-alpha
DBPLT3
GPIbA
VWDP
HGNC (Hugo) GP1BA
LocusID (NCBI) 2811
Atlas_Id 46312
Location 17p13.2  [Link to chromosome band 17p13]
Location_base_pair Starts at 4932275 and ends at 4935030 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GP1BA   4439
LRG (Locus Reference Genomic)LRG_480
Cards
Entrez_Gene (NCBI)GP1BA  2811  glycoprotein Ib platelet alpha subunit
AliasesBDPLT1; BDPLT3; BSS; CD42B; 
CD42b-alpha; DBPLT3; GP1B; GPIbA; GPIbalpha; VWDP
GeneCards (Weizmann)GP1BA
Ensembl hg19 (Hinxton)ENSG00000185245 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000185245 [Gene_View]  chr17:4932275-4935030 [Contig_View]  GP1BA [Vega]
ICGC DataPortalENSG00000185245
TCGA cBioPortalGP1BA
AceView (NCBI)GP1BA
Genatlas (Paris)GP1BA
WikiGenes2811
SOURCE (Princeton)GP1BA
Genetics Home Reference (NIH)GP1BA
Genomic and cartography
GoldenPath hg38 (UCSC)GP1BA  -     chr17:4932275-4935030 +  17p13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GP1BA  -     17p13.2   [Description]    (hg19-Feb_2009)
EnsemblGP1BA - 17p13.2 [CytoView hg19]  GP1BA - 17p13.2 [CytoView hg38]
Mapping of homologs : NCBIGP1BA [Mapview hg19]  GP1BA [Mapview hg38]
OMIM153670   177820   231200   258660   606672   
Gene and transcription
Genbank (Entrez)AI357061 BC027955 BE463855 DQ890943 DQ894105
RefSeq transcript (Entrez)NM_000173
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GP1BA
Cluster EST : UnigeneHs.1472 [ NCBI ]
CGAP (NCI)Hs.1472
Alternative Splicing GalleryENSG00000185245
Gene ExpressionGP1BA [ NCBI-GEO ]   GP1BA [ EBI - ARRAY_EXPRESS ]   GP1BA [ SEEK ]   GP1BA [ MEM ]
Gene Expression Viewer (FireBrowse)GP1BA [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2811
GTEX Portal (Tissue expression)GP1BA
Protein : pattern, domain, 3D structure
UniProt/SwissProtP07359   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP07359  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP07359
Splice isoforms : SwissVarP07359
PhosPhoSitePlusP07359
Domaine pattern : Prosite (Expaxy)LRR (PS51450)   
Domains : Interpro (EBI)Cys-rich_flank_reg_C    L_dom-like    Leu-rich_rpt    Leu-rich_rpt_typical-subtyp    LRRNT   
Domain families : Pfam (Sanger)LRR_8 (PF13855)    LRRNT (PF01462)   
Domain families : Pfam (NCBI)pfam13855    pfam01462   
Domain families : Smart (EMBL)LRR_TYP (SM00369)  LRRCT (SM00082)  LRRNT (SM00013)  
Conserved Domain (NCBI)GP1BA
DMDM Disease mutations2811
Blocks (Seattle)GP1BA
PDB (SRS)1GWB    1K13    1M0Z    1M10    1OOK    1P8V    1P9A    1QYY    1SQ0    1U0N    2BP3    3P72    3PMH    4C2A    4C2B    4CH2    4CH8    4MGX    4YR6   
PDB (PDBSum)1GWB    1K13    1M0Z    1M10    1OOK    1P8V    1P9A    1QYY    1SQ0    1U0N    2BP3    3P72    3PMH    4C2A    4C2B    4CH2    4CH8    4MGX    4YR6   
PDB (IMB)1GWB    1K13    1M0Z    1M10    1OOK    1P8V    1P9A    1QYY    1SQ0    1U0N    2BP3    3P72    3PMH    4C2A    4C2B    4CH2    4CH8    4MGX    4YR6   
PDB (RSDB)1GWB    1K13    1M0Z    1M10    1OOK    1P8V    1P9A    1QYY    1SQ0    1U0N    2BP3    3P72    3PMH    4C2A    4C2B    4CH2    4CH8    4MGX    4YR6   
Structural Biology KnowledgeBase1GWB    1K13    1M0Z    1M10    1OOK    1P8V    1P9A    1QYY    1SQ0    1U0N    2BP3    3P72    3PMH    4C2A    4C2B    4CH2    4CH8    4MGX    4YR6   
SCOP (Structural Classification of Proteins)1GWB    1K13    1M0Z    1M10    1OOK    1P8V    1P9A    1QYY    1SQ0    1U0N    2BP3    3P72    3PMH    4C2A    4C2B    4CH2    4CH8    4MGX    4YR6   
CATH (Classification of proteins structures)1GWB    1K13    1M0Z    1M10    1OOK    1P8V    1P9A    1QYY    1SQ0    1U0N    2BP3    3P72    3PMH    4C2A    4C2B    4CH2    4CH8    4MGX    4YR6   
SuperfamilyP07359
Human Protein AtlasENSG00000185245
Peptide AtlasP07359
HPRD01976
IPIIPI00748955   IPI00943099   
Protein Interaction databases
DIP (DOE-UCLA)P07359
IntAct (EBI)P07359
FunCoupENSG00000185245
BioGRIDGP1BA
STRING (EMBL)GP1BA
ZODIACGP1BA
Ontologies - Pathways
QuickGOP07359
Ontology : AmiGOcell morphogenesis  protein kinase inhibitor activity  protein binding  cytoplasm  plasma membrane  plasma membrane  integral component of plasma membrane  negative regulation of protein kinase activity  cell adhesion  cell surface receptor signaling pathway  blood coagulation  blood coagulation  blood coagulation, intrinsic pathway  cell surface  thrombin-activated receptor activity  membrane  cytokine-mediated signaling pathway  platelet activation  regulation of blood coagulation  anchored component of external side of plasma membrane  fibrinolysis  negative regulation of JAK-STAT cascade  extracellular exosome  thrombin-activated receptor signaling pathway  platelet aggregation  
Ontology : EGO-EBIcell morphogenesis  protein kinase inhibitor activity  protein binding  cytoplasm  plasma membrane  plasma membrane  integral component of plasma membrane  negative regulation of protein kinase activity  cell adhesion  cell surface receptor signaling pathway  blood coagulation  blood coagulation  blood coagulation, intrinsic pathway  cell surface  thrombin-activated receptor activity  membrane  cytokine-mediated signaling pathway  platelet activation  regulation of blood coagulation  anchored component of external side of plasma membrane  fibrinolysis  negative regulation of JAK-STAT cascade  extracellular exosome  thrombin-activated receptor signaling pathway  platelet aggregation  
Pathways : KEGGECM-receptor interaction    Hematopoietic cell lineage   
NDEx NetworkGP1BA
Atlas of Cancer Signalling NetworkGP1BA
Wikipedia pathwaysGP1BA
Orthology - Evolution
OrthoDB2811
GeneTree (enSembl)ENSG00000185245
Phylogenetic Trees/Animal Genes : TreeFamGP1BA
HOVERGENP07359
HOGENOMP07359
Homologs : HomoloGeneGP1BA
Homology/Alignments : Family Browser (UCSC)GP1BA
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGP1BA [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GP1BA
dbVarGP1BA
ClinVarGP1BA
1000_GenomesGP1BA 
Exome Variant ServerGP1BA
ExAC (Exome Aggregation Consortium)GP1BA (select the gene name)
Genetic variants : HAPMAP2811
Genomic Variants (DGV)GP1BA [DGVbeta]
DECIPHERGP1BA [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGP1BA 
Mutations
ICGC Data PortalGP1BA 
TCGA Data PortalGP1BA 
Broad Tumor PortalGP1BA
OASIS PortalGP1BA [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGP1BA  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGP1BA
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)EAHAD Coagulation Factor Variant Databases
BioMutasearch GP1BA
DgiDB (Drug Gene Interaction Database)GP1BA
DoCM (Curated mutations)GP1BA (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GP1BA (select a term)
intoGenGP1BA
Cancer3DGP1BA(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM153670    177820    231200    258660    606672   
Orphanet796    8692    10700   
MedgenGP1BA
Genetic Testing Registry GP1BA
NextProtP07359 [Medical]
TSGene2811
GENETestsGP1BA
Target ValidationGP1BA
Huge Navigator GP1BA [HugePedia]
snp3D : Map Gene to Disease2811
BioCentury BCIQGP1BA
ClinGenGP1BA
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2811
Chemical/Pharm GKB GenePA178
Clinical trialGP1BA
Miscellaneous
canSAR (ICR)GP1BA (select the gene name)
Probes
Litterature
PubMed306 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGP1BA
EVEXGP1BA
GoPubMedGP1BA
iHOPGP1BA
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:35:43 CEST 2017

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