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GP6 (glycoprotein VI platelet)

Identity

Alias_namesglycoprotein VI (platelet)
Alias_symbol (synonym)GPVI
Other aliasBDPLT11
GPIV
HGNC (Hugo) GP6
LocusID (NCBI) 51206
Atlas_Id 63918
Location 19q13.42  [Link to chromosome band 19q13]
Location_base_pair Starts at 55013707 and ends at 55038264 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GP6   14388
LRG (Locus Reference Genomic)LRG_560
Cards
Entrez_Gene (NCBI)GP6  51206  glycoprotein VI platelet
AliasesBDPLT11; GPIV; GPVI
GeneCards (Weizmann)GP6
Ensembl hg19 (Hinxton)ENSG00000088053 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000088053 [Gene_View]  chr19:55013707-55038264 [Contig_View]  GP6 [Vega]
ICGC DataPortalENSG00000088053
TCGA cBioPortalGP6
AceView (NCBI)GP6
Genatlas (Paris)GP6
WikiGenes51206
SOURCE (Princeton)GP6
Genetics Home Reference (NIH)GP6
Genomic and cartography
GoldenPath hg38 (UCSC)GP6  -     chr19:55013707-55038264 -  19q13.42   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GP6  -     19q13.42   [Description]    (hg19-Feb_2009)
EnsemblGP6 - 19q13.42 [CytoView hg19]  GP6 - 19q13.42 [CytoView hg38]
Mapping of homologs : NCBIGP6 [Mapview hg19]  GP6 [Mapview hg38]
OMIM605546   614201   
Gene and transcription
Genbank (Entrez)AB035073 AB043819 AB043820 AB043821 BC069485
RefSeq transcript (Entrez)NM_001083899 NM_001256017 NM_016363
RefSeq genomic (Entrez)NC_000019 NC_018930 NG_031963 NT_187693 NW_003571054 NW_003571055 NW_003571056 NW_003571057 NW_003571058 NW_003571059 NW_003571060 NW_003571061
Consensus coding sequences : CCDS (NCBI)GP6
Cluster EST : UnigeneHs.661752 [ NCBI ]
CGAP (NCI)Hs.661752
Alternative Splicing GalleryENSG00000088053
Gene ExpressionGP6 [ NCBI-GEO ]   GP6 [ EBI - ARRAY_EXPRESS ]   GP6 [ SEEK ]   GP6 [ MEM ]
Gene Expression Viewer (FireBrowse)GP6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51206
GTEX Portal (Tissue expression)GP6
Human Protein AtlasENSG00000088053-GP6 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9HCN6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9HCN6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9HCN6
Splice isoforms : SwissVarQ9HCN6
PhosPhoSitePlusQ9HCN6
Domains : Interpro (EBI)Ig-like_dom    Ig-like_fold    Ig_sub    Ig_sub2   
Domain families : Pfam (Sanger)Ig_2 (PF13895)   
Domain families : Pfam (NCBI)pfam13895   
Domain families : Smart (EMBL)IG (SM00409)  IGc2 (SM00408)  
Conserved Domain (NCBI)GP6
DMDM Disease mutations51206
Blocks (Seattle)GP6
PDB (SRS)2GI7   
PDB (PDBSum)2GI7   
PDB (IMB)2GI7   
PDB (RSDB)2GI7   
Structural Biology KnowledgeBase2GI7   
SCOP (Structural Classification of Proteins)2GI7   
CATH (Classification of proteins structures)2GI7   
SuperfamilyQ9HCN6
Human Protein Atlas [tissue]ENSG00000088053-GP6 [tissue]
Peptide AtlasQ9HCN6
HPRD10406
IPIIPI00737479   IPI00163074   IPI00102300   
Protein Interaction databases
DIP (DOE-UCLA)Q9HCN6
IntAct (EBI)Q9HCN6
FunCoupENSG00000088053
BioGRIDGP6
STRING (EMBL)GP6
ZODIACGP6
Ontologies - Pathways
QuickGOQ9HCN6
Ontology : AmiGOreceptor activity  transmembrane signaling receptor activity  protein binding  collagen binding  plasma membrane  integral component of plasma membrane  enzyme linked receptor protein signaling pathway  blood coagulation  cell surface  platelet activation  platelet activation  leukocyte migration  extracellular exosome  tetraspanin-enriched microdomain  
Ontology : EGO-EBIreceptor activity  transmembrane signaling receptor activity  protein binding  collagen binding  plasma membrane  integral component of plasma membrane  enzyme linked receptor protein signaling pathway  blood coagulation  cell surface  platelet activation  platelet activation  leukocyte migration  extracellular exosome  tetraspanin-enriched microdomain  
Pathways : KEGGECM-receptor interaction   
NDEx NetworkGP6
Atlas of Cancer Signalling NetworkGP6
Wikipedia pathwaysGP6
Orthology - Evolution
OrthoDB51206
GeneTree (enSembl)ENSG00000088053
Phylogenetic Trees/Animal Genes : TreeFamGP6
HOVERGENQ9HCN6
HOGENOMQ9HCN6
Homologs : HomoloGeneGP6
Homology/Alignments : Family Browser (UCSC)GP6
Gene fusions - Rearrangements
Tumor Fusion PortalGP6
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGP6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GP6
dbVarGP6
ClinVarGP6
1000_GenomesGP6 
Exome Variant ServerGP6
ExAC (Exome Aggregation Consortium)ENSG00000088053
GNOMAD BrowserENSG00000088053
Genetic variants : HAPMAP51206
Genomic Variants (DGV)GP6 [DGVbeta]
DECIPHERGP6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGP6 
Mutations
ICGC Data PortalGP6 
TCGA Data PortalGP6 
Broad Tumor PortalGP6
OASIS PortalGP6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGP6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGP6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GP6
DgiDB (Drug Gene Interaction Database)GP6
DoCM (Curated mutations)GP6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GP6 (select a term)
intoGenGP6
Cancer3DGP6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605546    614201   
Orphanet13902   
DisGeNETGP6
MedgenGP6
Genetic Testing Registry GP6
NextProtQ9HCN6 [Medical]
TSGene51206
GENETestsGP6
Target ValidationGP6
Huge Navigator GP6 [HugePedia]
snp3D : Map Gene to Disease51206
BioCentury BCIQGP6
ClinGenGP6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51206
Chemical/Pharm GKB GenePA28824
Clinical trialGP6
Miscellaneous
canSAR (ICR)GP6 (select the gene name)
Probes
Litterature
PubMed171 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGP6
EVEXGP6
GoPubMedGP6
iHOPGP6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 13:38:39 CET 2017

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