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GPAA1 (glycosylphosphatidylinositol anchor attachment 1)

Identity

Alias_namesanchor attachment protein 1 (Gaa1p, yeast) homolog
GPAA1P anchor attachment protein 1 homolog (yeast)
glycosylphosphatidylinositol anchor attachment protein 1 homolog (yeast)
Alias_symbol (synonym)GAA1
hGAA1
Other alias
HGNC (Hugo) GPAA1
LocusID (NCBI) 8733
Atlas_Id 43871
Location 8q24.3  [Link to chromosome band 8q24]
Location_base_pair Starts at 145137524 and ends at 145141119 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
GPAA1 (8q24.3) / CD24 (Yq11.222)MROH1 (8q24.3) / GPAA1 (8q24.3)HEATR7A GPAA1 8q24.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GPAA1   4446
Cards
Entrez_Gene (NCBI)GPAA1  8733  glycosylphosphatidylinositol anchor attachment 1
AliasesGAA1; hGAA1
GeneCards (Weizmann)GPAA1
Ensembl hg19 (Hinxton)ENSG00000197858 [Gene_View]  chr8:145137524-145141119 [Contig_View]  GPAA1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000197858 [Gene_View]  chr8:145137524-145141119 [Contig_View]  GPAA1 [Vega]
ICGC DataPortalENSG00000197858
TCGA cBioPortalGPAA1
AceView (NCBI)GPAA1
Genatlas (Paris)GPAA1
WikiGenes8733
SOURCE (Princeton)GPAA1
Genetics Home Reference (NIH)GPAA1
Genomic and cartography
GoldenPath hg19 (UCSC)GPAA1  -     chr8:145137524-145141119 +  8q24.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)GPAA1  -     8q24.3   [Description]    (hg38-Dec_2013)
EnsemblGPAA1 - 8q24.3 [CytoView hg19]  GPAA1 - 8q24.3 [CytoView hg38]
Mapping of homologs : NCBIGPAA1 [Mapview hg19]  GPAA1 [Mapview hg38]
OMIM603048   
Gene and transcription
Genbank (Entrez)AB002135 AB006969 AK312759 AL157437 BC003171
RefSeq transcript (Entrez)NM_003801
RefSeq genomic (Entrez)NC_000008 NC_018919 NT_008046 NW_004929340
Consensus coding sequences : CCDS (NCBI)GPAA1
Cluster EST : UnigeneHs.627962 [ NCBI ]
CGAP (NCI)Hs.627962
Alternative Splicing GalleryENSG00000197858
Gene ExpressionGPAA1 [ NCBI-GEO ]   GPAA1 [ EBI - ARRAY_EXPRESS ]   GPAA1 [ SEEK ]   GPAA1 [ MEM ]
Gene Expression Viewer (FireBrowse)GPAA1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8733
GTEX Portal (Tissue expression)GPAA1
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43292   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO43292  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO43292
Splice isoforms : SwissVarO43292
PhosPhoSitePlusO43292
Domains : Interpro (EBI)Gaa1   
Domain families : Pfam (Sanger)Gaa1 (PF04114)   
Domain families : Pfam (NCBI)pfam04114   
Conserved Domain (NCBI)GPAA1
DMDM Disease mutations8733
Blocks (Seattle)GPAA1
SuperfamilyO43292
Human Protein AtlasENSG00000197858
Peptide AtlasO43292
HPRD04334
IPIIPI00021594   IPI00400944   IPI00789883   IPI00979924   IPI00978533   IPI00979031   IPI00979149   IPI00791388   IPI01015615   IPI00976100   
Protein Interaction databases
DIP (DOE-UCLA)O43292
IntAct (EBI)O43292
FunCoupENSG00000197858
BioGRIDGPAA1
STRING (EMBL)GPAA1
ZODIACGPAA1
Ontologies - Pathways
QuickGOO43292
Ontology : AmiGOGPI-anchor transamidase activity  protein binding  endoplasmic reticulum membrane  protein complex assembly  protein retention in ER lumen  tubulin binding  membrane  attachment of GPI anchor to protein  attachment of GPI anchor to protein  GPI anchor binding  GPI-anchor transamidase complex  
Ontology : EGO-EBIGPI-anchor transamidase activity  protein binding  endoplasmic reticulum membrane  protein complex assembly  protein retention in ER lumen  tubulin binding  membrane  attachment of GPI anchor to protein  attachment of GPI anchor to protein  GPI anchor binding  GPI-anchor transamidase complex  
Pathways : KEGGGlycosylphosphatidylinositol(GPI)-anchor biosynthesis   
NDEx NetworkGPAA1
Atlas of Cancer Signalling NetworkGPAA1
Wikipedia pathwaysGPAA1
Orthology - Evolution
OrthoDB8733
GeneTree (enSembl)ENSG00000197858
Phylogenetic Trees/Animal Genes : TreeFamGPAA1
HOVERGENO43292
HOGENOMO43292
Homologs : HomoloGeneGPAA1
Homology/Alignments : Family Browser (UCSC)GPAA1
Gene fusions - Rearrangements
Fusion : MitelmanGPAA1/CD24 [8q24.3/Yq11.222]  
Fusion : MitelmanMROH1/GPAA1 [8q24.3/8q24.3]  [t(8;8)(q24;q24)]  
Fusion: TCGAHEATR7A GPAA1 8q24.3 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGPAA1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GPAA1
dbVarGPAA1
ClinVarGPAA1
1000_GenomesGPAA1 
Exome Variant ServerGPAA1
ExAC (Exome Aggregation Consortium)GPAA1 (select the gene name)
Genetic variants : HAPMAP8733
Genomic Variants (DGV)GPAA1 [DGVbeta]
DECIPHER (Syndromes)8:145137524-145141119  ENSG00000197858
CONAN: Copy Number AnalysisGPAA1 
Mutations
ICGC Data PortalGPAA1 
TCGA Data PortalGPAA1 
Broad Tumor PortalGPAA1
OASIS PortalGPAA1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGPAA1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGPAA1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GPAA1
DgiDB (Drug Gene Interaction Database)GPAA1
DoCM (Curated mutations)GPAA1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GPAA1 (select a term)
intoGenGPAA1
Cancer3DGPAA1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603048   
Orphanet
MedgenGPAA1
Genetic Testing Registry GPAA1
NextProtO43292 [Medical]
TSGene8733
GENETestsGPAA1
Huge Navigator GPAA1 [HugePedia]
snp3D : Map Gene to Disease8733
BioCentury BCIQGPAA1
ClinGenGPAA1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8733
Chemical/Pharm GKB GenePA28827
Clinical trialGPAA1
Miscellaneous
canSAR (ICR)GPAA1 (select the gene name)
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGPAA1
EVEXGPAA1
GoPubMedGPAA1
iHOPGPAA1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:02:48 CEST 2017

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