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GPAM (glycerol-3-phosphate acyltransferase, mitochondrial)

Identity

Alias_namesmitochondrial
Alias_symbol (synonym)KIAA1560
MGC26846
GPAT1
Other aliasGPAT
HGNC (Hugo) GPAM
LocusID (NCBI) 57678
Atlas_Id 52786
Location 10q25.2  [Link to chromosome band 10q25]
Location_base_pair Starts at 112149864 and ends at 112183779 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
GPAM (10q25.2) / PRKCB (16p12.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GPAM   24865
Cards
Entrez_Gene (NCBI)GPAM  57678  glycerol-3-phosphate acyltransferase, mitochondrial
AliasesGPAT; GPAT1
GeneCards (Weizmann)GPAM
Ensembl hg19 (Hinxton)ENSG00000119927 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000119927 [Gene_View]  chr10:112149864-112183779 [Contig_View]  GPAM [Vega]
ICGC DataPortalENSG00000119927
TCGA cBioPortalGPAM
AceView (NCBI)GPAM
Genatlas (Paris)GPAM
WikiGenes57678
SOURCE (Princeton)GPAM
Genetics Home Reference (NIH)GPAM
Genomic and cartography
GoldenPath hg38 (UCSC)GPAM  -     chr10:112149864-112183779 -  10q25.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GPAM  -     10q25.2   [Description]    (hg19-Feb_2009)
EnsemblGPAM - 10q25.2 [CytoView hg19]  GPAM - 10q25.2 [CytoView hg38]
Mapping of homologs : NCBIGPAM [Mapview hg19]  GPAM [Mapview hg38]
OMIM602395   
Gene and transcription
Genbank (Entrez)AB046780 AK025752 AK172782 AK172799 AL598680
RefSeq transcript (Entrez)NM_001244949 NM_020918
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GPAM
Cluster EST : UnigeneHs.42586 [ NCBI ]
CGAP (NCI)Hs.42586
Alternative Splicing GalleryENSG00000119927
Gene ExpressionGPAM [ NCBI-GEO ]   GPAM [ EBI - ARRAY_EXPRESS ]   GPAM [ SEEK ]   GPAM [ MEM ]
Gene Expression Viewer (FireBrowse)GPAM [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57678
GTEX Portal (Tissue expression)GPAM
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9HCL2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9HCL2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9HCL2
Splice isoforms : SwissVarQ9HCL2
Catalytic activity : Enzyme2.3.1.15 [ Enzyme-Expasy ]   2.3.1.152.3.1.15 [ IntEnz-EBI ]   2.3.1.15 [ BRENDA ]   2.3.1.15 [ KEGG ]   
PhosPhoSitePlusQ9HCL2
Domains : Interpro (EBI)GPAT/DHAPAT    GPAT_PlsB    Plipid/glycerol_acylTrfase   
Domain families : Pfam (Sanger)Acyltransferase (PF01553)   
Domain families : Pfam (NCBI)pfam01553   
Domain families : Smart (EMBL)PlsC (SM00563)  
Conserved Domain (NCBI)GPAM
DMDM Disease mutations57678
Blocks (Seattle)GPAM
SuperfamilyQ9HCL2
Human Protein AtlasENSG00000119927
Peptide AtlasQ9HCL2
HPRD03865
IPIIPI00844249   IPI00640749   
Protein Interaction databases
DIP (DOE-UCLA)Q9HCL2
IntAct (EBI)Q9HCL2
FunCoupENSG00000119927
BioGRIDGPAM
STRING (EMBL)GPAM
ZODIACGPAM
Ontologies - Pathways
QuickGOQ9HCL2
Ontology : AmiGOglycerol-3-phosphate O-acyltransferase activity  glycerol-3-phosphate O-acyltransferase activity  mitochondrial outer membrane  mitochondrial inner membrane  plasma membrane  fatty acid metabolic process  acyl-CoA metabolic process  phosphatidic acid biosynthetic process  response to glucose  integral component of membrane  CDP-diacylglycerol biosynthetic process  triglyceride biosynthetic process  triglyceride biosynthetic process  positive regulation of multicellular organism growth  positive regulation of activated T cell proliferation  regulation of cytokine secretion  defense response to virus  fatty acid homeostasis  phospholipid homeostasis  negative regulation of activation-induced cell death of T cells  interleukin-2 secretion  
Ontology : EGO-EBIglycerol-3-phosphate O-acyltransferase activity  glycerol-3-phosphate O-acyltransferase activity  mitochondrial outer membrane  mitochondrial inner membrane  plasma membrane  fatty acid metabolic process  acyl-CoA metabolic process  phosphatidic acid biosynthetic process  response to glucose  integral component of membrane  CDP-diacylglycerol biosynthetic process  triglyceride biosynthetic process  triglyceride biosynthetic process  positive regulation of multicellular organism growth  positive regulation of activated T cell proliferation  regulation of cytokine secretion  defense response to virus  fatty acid homeostasis  phospholipid homeostasis  negative regulation of activation-induced cell death of T cells  interleukin-2 secretion  
Pathways : KEGGGlycerolipid metabolism    Glycerophospholipid metabolism   
NDEx NetworkGPAM
Atlas of Cancer Signalling NetworkGPAM
Wikipedia pathwaysGPAM
Orthology - Evolution
OrthoDB57678
GeneTree (enSembl)ENSG00000119927
Phylogenetic Trees/Animal Genes : TreeFamGPAM
HOVERGENQ9HCL2
HOGENOMQ9HCL2
Homologs : HomoloGeneGPAM
Homology/Alignments : Family Browser (UCSC)GPAM
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGPAM [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GPAM
dbVarGPAM
ClinVarGPAM
1000_GenomesGPAM 
Exome Variant ServerGPAM
ExAC (Exome Aggregation Consortium)GPAM (select the gene name)
Genetic variants : HAPMAP57678
Genomic Variants (DGV)GPAM [DGVbeta]
DECIPHERGPAM [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGPAM 
Mutations
ICGC Data PortalGPAM 
TCGA Data PortalGPAM 
Broad Tumor PortalGPAM
OASIS PortalGPAM [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGPAM  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGPAM
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch GPAM
DgiDB (Drug Gene Interaction Database)GPAM
DoCM (Curated mutations)GPAM (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GPAM (select a term)
intoGenGPAM
Cancer3DGPAM(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602395   
Orphanet
MedgenGPAM
Genetic Testing Registry GPAM
NextProtQ9HCL2 [Medical]
TSGene57678
GENETestsGPAM
Target ValidationGPAM
Huge Navigator GPAM [HugePedia]
snp3D : Map Gene to Disease57678
BioCentury BCIQGPAM
ClinGenGPAM
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57678
Chemical/Pharm GKB GenePA134983031
Clinical trialGPAM
Miscellaneous
canSAR (ICR)GPAM (select the gene name)
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGPAM
EVEXGPAM
GoPubMedGPAM
iHOPGPAM
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:35:44 CEST 2017

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