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GPAM (glycerol-3-phosphate acyltransferase, mitochondrial)

Identity

Alias (NCBI)GPAT
GPAT1
HGNC (Hugo) GPAM
HGNC Alias symbKIAA1560
MGC26846
GPAT1
HGNC Alias nameglycerol-3-phosphate acyltransferase 1, mitochondrial
LocusID (NCBI) 57678
Atlas_Id 52786
Location 10q25.2  [Link to chromosome band 10q25]
Location_base_pair Starts at 112149865 and ends at 112183765 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
GPAM (10q25.2) / PRKCB (16p12.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)GPAM   24865
Cards
Entrez_Gene (NCBI)GPAM    glycerol-3-phosphate acyltransferase, mitochondrial
AliasesGPAT; GPAT1
GeneCards (Weizmann)GPAM
Ensembl hg19 (Hinxton)ENSG00000119927 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000119927 [Gene_View]  ENSG00000119927 [Sequence]  chr10:112149865-112183765 [Contig_View]  GPAM [Vega]
ICGC DataPortalENSG00000119927
TCGA cBioPortalGPAM
AceView (NCBI)GPAM
Genatlas (Paris)GPAM
SOURCE (Princeton)GPAM
Genetics Home Reference (NIH)GPAM
Genomic and cartography
GoldenPath hg38 (UCSC)GPAM  -     chr10:112149865-112183765 -  10q25.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GPAM  -     10q25.2   [Description]    (hg19-Feb_2009)
GoldenPathGPAM - 10q25.2 [CytoView hg19]  GPAM - 10q25.2 [CytoView hg38]
ImmunoBaseENSG00000119927
Genome Data Viewer NCBIGPAM [Mapview hg19]  
OMIM602395   
Gene and transcription
Genbank (Entrez)AB046780 AK025752 AK172782 AK172799 AL598680
RefSeq transcript (Entrez)NM_001244949 NM_020918
Consensus coding sequences : CCDS (NCBI)GPAM
Gene ExpressionGPAM [ NCBI-GEO ]   GPAM [ EBI - ARRAY_EXPRESS ]   GPAM [ SEEK ]   GPAM [ MEM ]
Gene Expression Viewer (FireBrowse)GPAM [ Firebrowse - Broad ]
GenevisibleExpression of GPAM in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57678
GTEX Portal (Tissue expression)GPAM
Human Protein AtlasENSG00000119927-GPAM [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9HCL2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9HCL2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9HCL2
PhosPhoSitePlusQ9HCL2
Domains : Interpro (EBI)GPAT/DHAPAT    GPAT/DHAPAT_LPLAT    GPAT_PlsB    Plipid/glycerol_acylTrfase   
Domain families : Pfam (Sanger)Acyltransferase (PF01553)   
Domain families : Pfam (NCBI)pfam01553   
Domain families : Smart (EMBL)PlsC (SM00563)  
Conserved Domain (NCBI)GPAM
SuperfamilyQ9HCL2
AlphaFold pdb e-kbQ9HCL2   
Human Protein Atlas [tissue]ENSG00000119927-GPAM [tissue]
HPRD03865
Protein Interaction databases
DIP (DOE-UCLA)Q9HCL2
IntAct (EBI)Q9HCL2
BioGRIDGPAM
STRING (EMBL)GPAM
ZODIACGPAM
Ontologies - Pathways
QuickGOQ9HCL2
Ontology : AmiGOregulation of cytokine production  glycerol-3-phosphate O-acyltransferase activity  glycerol-3-phosphate O-acyltransferase activity  glycerol-3-phosphate O-acyltransferase activity  protein binding  mitochondrial outer membrane  plasma membrane  glycerol-3-phosphate metabolic process  fatty acid metabolic process  acyl-CoA metabolic process  diacylglycerol biosynthetic process  phosphatidic acid biosynthetic process  phosphatidic acid biosynthetic process  phosphatidylglycerol biosynthetic process  phospholipid biosynthetic process  response to glucose  integral component of membrane  CDP-diacylglycerol biosynthetic process  regulation of lipid metabolic process  triglyceride biosynthetic process  triglyceride biosynthetic process  triglyceride biosynthetic process  mitochondrial membrane  regulation of intracellular estrogen receptor signaling pathway  positive regulation of multicellular organism growth  positive regulation of activated T cell proliferation  defense response to virus  fatty acid homeostasis  phospholipid homeostasis  negative regulation of activation-induced cell death of T cells  sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity  
Ontology : EGO-EBIregulation of cytokine production  glycerol-3-phosphate O-acyltransferase activity  glycerol-3-phosphate O-acyltransferase activity  glycerol-3-phosphate O-acyltransferase activity  protein binding  mitochondrial outer membrane  plasma membrane  glycerol-3-phosphate metabolic process  fatty acid metabolic process  acyl-CoA metabolic process  diacylglycerol biosynthetic process  phosphatidic acid biosynthetic process  phosphatidic acid biosynthetic process  phosphatidylglycerol biosynthetic process  phospholipid biosynthetic process  response to glucose  integral component of membrane  CDP-diacylglycerol biosynthetic process  regulation of lipid metabolic process  triglyceride biosynthetic process  triglyceride biosynthetic process  triglyceride biosynthetic process  mitochondrial membrane  regulation of intracellular estrogen receptor signaling pathway  positive regulation of multicellular organism growth  positive regulation of activated T cell proliferation  defense response to virus  fatty acid homeostasis  phospholipid homeostasis  negative regulation of activation-induced cell death of T cells  sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity  
Pathways : KEGGGlycerolipid metabolism    Glycerophospholipid metabolism   
NDEx NetworkGPAM
Atlas of Cancer Signalling NetworkGPAM
Wikipedia pathwaysGPAM
Orthology - Evolution
OrthoDB57678
GeneTree (enSembl)ENSG00000119927
Phylogenetic Trees/Animal Genes : TreeFamGPAM
Homologs : HomoloGeneGPAM
Homology/Alignments : Family Browser (UCSC)GPAM
Gene fusions - Rearrangements
Fusion : QuiverGPAM
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGPAM [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GPAM
dbVarGPAM
ClinVarGPAM
MonarchGPAM
1000_GenomesGPAM 
Exome Variant ServerGPAM
GNOMAD BrowserENSG00000119927
Varsome BrowserGPAM
ACMGGPAM variants
VarityQ9HCL2
Genomic Variants (DGV)GPAM [DGVbeta]
DECIPHERGPAM [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGPAM 
Mutations
ICGC Data PortalGPAM 
TCGA Data PortalGPAM 
Broad Tumor PortalGPAM
OASIS PortalGPAM [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGPAM  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DGPAM
Mutations and Diseases : HGMDGPAM
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaGPAM
DgiDB (Drug Gene Interaction Database)GPAM
DoCM (Curated mutations)GPAM
CIViC (Clinical Interpretations of Variants in Cancer)GPAM
Cancer3DGPAM
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602395   
Orphanet
DisGeNETGPAM
MedgenGPAM
Genetic Testing Registry GPAM
NextProtQ9HCL2 [Medical]
GENETestsGPAM
Target ValidationGPAM
Huge Navigator GPAM [HugePedia]
ClinGenGPAM
Clinical trials, drugs, therapy
MyCancerGenomeGPAM
Protein Interactions : CTDGPAM
Pharm GKB GenePA134983031
Pharm GKB PathwaysPA165948566   
PharosQ9HCL2
Clinical trialGPAM
Miscellaneous
canSAR (ICR)GPAM
HarmonizomeGPAM
DataMed IndexGPAM
Probes
Litterature
PubMed39 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXGPAM
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:11:13 CEST 2021

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