Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 57678
MIM: 602395
HGNC: 24865
Ensembl: ENSG00000119927
Variants:
dbSNP: 57678
ClinVar: 57678
TCGA: ENSG00000119927
COSMIC: GPAM
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000119927 | ENST00000348367 | Q9HCL2 |
| ENSG00000119927 | ENST00000369425 | Q5VW52 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA33744 | PRKAA1 | Gene | Pathway | associated | 22722338 | ||
| PA33745 | PRKAA2 | Gene | Pathway | associated | 22722338 | ||
| PA33746 | PRKAB1 | Gene | Pathway | associated | 22722338 | ||
| PA33747 | PRKAB2 | Gene | Pathway | associated | 22722338 | ||
| PA33751 | PRKAG1 | Gene | Pathway | associated | 22722338 | ||
| PA33752 | PRKAG2 | Gene | Pathway | associated | 22722338 | ||
| PA33753 | PRKAG3 | Gene | Pathway | associated | 22722338 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36522428 | 2023 | Structural basis of the acyl-transfer mechanism of human GPAT1. | 2 |
| 36522428 | 2023 | Structural basis of the acyl-transfer mechanism of human GPAT1. | 2 |
| 35662157 | 2022 | [Identification of GPAT1-dependent mitochondrial metabolism as a novel therapeutic target for AML]. | 1 |
| 35662157 | 2022 | [Identification of GPAT1-dependent mitochondrial metabolism as a novel therapeutic target for AML]. | 1 |
| 33347879 | 2021 | Exome-Wide Association Study on Alanine Aminotransferase Identifies Sequence Variants in the GPAM and APOE Associated With Fatty Liver Disease. | 44 |
| 34216018 | 2021 | Genetic Variation in the Mitochondrial Glycerol-3-Phosphate Acyltransferase Is Associated With Liver Injury. | 7 |
| 33347879 | 2021 | Exome-Wide Association Study on Alanine Aminotransferase Identifies Sequence Variants in the GPAM and APOE Associated With Fatty Liver Disease. | 44 |
| 34216018 | 2021 | Genetic Variation in the Mitochondrial Glycerol-3-Phosphate Acyltransferase Is Associated With Liver Injury. | 7 |
| 28652252 | 2017 | Glycerol-3-phosphate Acyltransferase 1 Promotes Tumor Cell Migration and Poor Survival in Ovarian Carcinoma. | 36 |
| 28652252 | 2017 | Glycerol-3-phosphate Acyltransferase 1 Promotes Tumor Cell Migration and Poor Survival in Ovarian Carcinoma. | 36 |
| 22070544 | 2012 | Integration of metabolomics and expression of glycerol-3-phosphate acyltransferase (GPAM) in breast cancer-link to patient survival, hormone receptor status, and metabolic profiling. | 36 |
| 22634312 | 2012 | Identification and functional characterization of human glycerol-3-phosphate acyltransferase 1 gene promoters. | 6 |
| 22070544 | 2012 | Integration of metabolomics and expression of glycerol-3-phosphate acyltransferase (GPAM) in breast cancer-link to patient survival, hormone receptor status, and metabolic profiling. | 36 |
| 22634312 | 2012 | Identification and functional characterization of human glycerol-3-phosphate acyltransferase 1 gene promoters. | 6 |
| 20453000 | 2010 | A Large-scale genetic association study of esophageal adenocarcinoma risk. | 26 |
Citation
Dessen P
GPAM (glycerol-3-phosphate acyltransferase, mitochondrial)
Atlas Genet Cytogenet Oncol Haematol. 2012-08-01
Online version: http://atlasgeneticsoncology.org/gene/52786/gpam
