Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

GPAT4 (glycerol-3-phosphate acyltransferase 4)

Identity

Alias (NCBI)1-AGPAT 6
AGPAT6
LPAAT-zeta
LPAATZ
TSARG7
HGNC (Hugo) GPAT4
HGNC Alias symbDKFZp586M1819
LPAAT-zeta
TSARG7
HGNC Alias namelysophosphatidic acid acyltransferase, zeta
HGNC Previous nameAGPAT6
HGNC Previous name1-acylglycerol-3-phosphate O-acyltransferase 6 (lysophosphatidic acid acyltransferase, zeta)
 1-acylglycerol-3-phosphate O-acyltransferase 6
LocusID (NCBI) 137964
Atlas_Id 77796
Location 8p11.21  [Link to chromosome band 8p11]
Location_base_pair Starts at 41578200 and ends at 41625001 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CDK2AP2 (11q13.2) / GPAT4 (8p11.21)GPAT4 (8p11.21) / ADAM9 (8p11.22)HGSNAT (8p11.21) / GPAT4 (8p11.21)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)GPAT4   20880
Cards
Entrez_Gene (NCBI)GPAT4    glycerol-3-phosphate acyltransferase 4
Aliases1-AGPAT; AGPAT6; LPAAT-zeta; LPAATZ; 
TSARG7
GeneCards (Weizmann)GPAT4
Ensembl hg19 (Hinxton)ENSG00000158669 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000158669 [Gene_View]  ENSG00000158669 [Sequence]  chr8:41578200-41625001 [Contig_View]  GPAT4 [Vega]
ICGC DataPortalENSG00000158669
TCGA cBioPortalGPAT4
AceView (NCBI)GPAT4
Genatlas (Paris)GPAT4
SOURCE (Princeton)GPAT4
Genetics Home Reference (NIH)GPAT4
Genomic and cartography
GoldenPath hg38 (UCSC)GPAT4  -     chr8:41578200-41625001 +  8p11.21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GPAT4  -     8p11.21   [Description]    (hg19-Feb_2009)
GoldenPathGPAT4 - 8p11.21 [CytoView hg19]  GPAT4 - 8p11.21 [CytoView hg38]
ImmunoBaseENSG00000158669
Genome Data Viewer NCBIGPAT4 [Mapview hg19]  
OMIM608143   
Gene and transcription
Genbank (Entrez)AF317516 AF406612 AL834255 AY358670 AY513610
RefSeq transcript (Entrez)NM_001363197 NM_001363198 NM_178819
Consensus coding sequences : CCDS (NCBI)GPAT4
Gene ExpressionGPAT4 [ NCBI-GEO ]   GPAT4 [ EBI - ARRAY_EXPRESS ]   GPAT4 [ SEEK ]   GPAT4 [ MEM ]
Gene Expression Viewer (FireBrowse)GPAT4 [ Firebrowse - Broad ]
GenevisibleExpression of GPAT4 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)137964
GTEX Portal (Tissue expression)GPAT4
Human Protein AtlasENSG00000158669-GPAT4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86UL3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86UL3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86UL3
PhosPhoSitePlusQ86UL3
Domains : Interpro (EBI)Plipid/glycerol_acylTrfase   
Domain families : Pfam (Sanger)Acyltransferase (PF01553)   
Domain families : Pfam (NCBI)pfam01553   
Domain families : Smart (EMBL)PlsC (SM00563)  
Conserved Domain (NCBI)GPAT4
SuperfamilyQ86UL3
AlphaFold pdb e-kbQ86UL3   
Human Protein Atlas [tissue]ENSG00000158669-GPAT4 [tissue]
HPRD12175
Protein Interaction databases
DIP (DOE-UCLA)Q86UL3
IntAct (EBI)Q86UL3
BioGRIDGPAT4
STRING (EMBL)GPAT4
ZODIACGPAT4
Ontologies - Pathways
QuickGOQ86UL3
Ontology : AmiGOglandular epithelial cell maturation  1-acylglycerol-3-phosphate O-acyltransferase activity  glycerol-3-phosphate O-acyltransferase activity  endoplasmic reticulum  endoplasmic reticulum  endoplasmic reticulum membrane  fatty acid metabolic process  acyl-CoA metabolic process  phosphatidic acid biosynthetic process  phosphatidylcholine biosynthetic process  lactation  lipid biosynthetic process  membrane  membrane  integral component of membrane  CDP-diacylglycerol biosynthetic process  triglyceride biosynthetic process  triglyceride biosynthetic process  regulation of multicellular organism growth  diacylglycerol metabolic process  sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity  
Ontology : EGO-EBIglandular epithelial cell maturation  1-acylglycerol-3-phosphate O-acyltransferase activity  glycerol-3-phosphate O-acyltransferase activity  endoplasmic reticulum  endoplasmic reticulum  endoplasmic reticulum membrane  fatty acid metabolic process  acyl-CoA metabolic process  phosphatidic acid biosynthetic process  phosphatidylcholine biosynthetic process  lactation  lipid biosynthetic process  membrane  membrane  integral component of membrane  CDP-diacylglycerol biosynthetic process  triglyceride biosynthetic process  triglyceride biosynthetic process  regulation of multicellular organism growth  diacylglycerol metabolic process  sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity  
NDEx NetworkGPAT4
Atlas of Cancer Signalling NetworkGPAT4
Wikipedia pathwaysGPAT4
Orthology - Evolution
OrthoDB137964
GeneTree (enSembl)ENSG00000158669
Phylogenetic Trees/Animal Genes : TreeFamGPAT4
Homologs : HomoloGeneGPAT4
Homology/Alignments : Family Browser (UCSC)GPAT4
Gene fusions - Rearrangements
Fusion : QuiverGPAT4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGPAT4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GPAT4
dbVarGPAT4
ClinVarGPAT4
MonarchGPAT4
1000_GenomesGPAT4 
Exome Variant ServerGPAT4
GNOMAD BrowserENSG00000158669
Varsome BrowserGPAT4
ACMGGPAT4 variants
VarityQ86UL3
Genomic Variants (DGV)GPAT4 [DGVbeta]
DECIPHERGPAT4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGPAT4 
Mutations
ICGC Data PortalGPAT4 
TCGA Data PortalGPAT4 
Broad Tumor PortalGPAT4
OASIS PortalGPAT4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGPAT4  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DGPAT4
Mutations and Diseases : HGMDGPAT4
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaGPAT4
DgiDB (Drug Gene Interaction Database)GPAT4
DoCM (Curated mutations)GPAT4
CIViC (Clinical Interpretations of Variants in Cancer)GPAT4
Cancer3DGPAT4
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608143   
Orphanet
DisGeNETGPAT4
MedgenGPAT4
Genetic Testing Registry GPAT4
NextProtQ86UL3 [Medical]
GENETestsGPAT4
Target ValidationGPAT4
Huge Navigator GPAT4 [HugePedia]
ClinGenGPAT4
Clinical trials, drugs, therapy
MyCancerGenomeGPAT4
Protein Interactions : CTDGPAT4
Pharm GKB GenePA142672637
PharosQ86UL3
Clinical trialGPAT4
Miscellaneous
canSAR (ICR)GPAT4
HarmonizomeGPAT4
DataMed IndexGPAT4
Probes
Litterature
PubMed35 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXGPAT4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 15:51:50 CEST 2021

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.