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GPATCH8 (G-patch domain containing 8)

Identity

Alias_namesKIAA0553
GPATC8
KIAA0553
Other alias
HGNC (Hugo) GPATCH8
LocusID (NCBI) 23131
Atlas_Id 54341
Location 17q21.31  [Link to chromosome band 17q21]
Location_base_pair Starts at 44395277 and ends at 44503602 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
DHX8 (17q21.31) / GPATCH8 (17q21.31)GPATCH8 (17q21.31) / C8orf46 (8q13.1)GPATCH8 (17q21.31) / COMTD1 (10q22.2)
GPATCH8 (17q21.31) / GPATCH8 (17q21.31)GPATCH8 (17q21.31) / HNRNPUL1 (19q13.2)GPATCH8 (17q21.31) / IRAK4 (12q12)
GPATCH8 (17q21.31) / MYO1D (17q11.2)GPATCH8 (17q21.31) / NPLOC4 (17q25.3)GPATCH8 (17q21.31) / SESN1 (6q21)
GPATCH8 (17q21.31) / ZMYM4 (1p34.3)RLF (1p34.2) / GPATCH8 (17q21.31)TMEM132E (17q12) / GPATCH8 (17q21.31)
TMEM98 (17q11.2) / GPATCH8 (17q21.31)DHX8 17q21.31 / GPATCH8 17q21.31GPATCH8 17q21.31 / COMTD1 10q22.2
GPATCH8 17q21.31 / MYO1D 17q11.2GPATCH8 17q21.31 / NPLOC4 17q25.3GPATCH8 17q21.31 / ZMYM4 1p34.3
RLF 1p34.2 / GPATCH8 17q21.31TMEM132E 17q12 / GPATCH8 17q21.31TMEM98 17q11.2 / GPATCH8 17q21.31

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GPATCH8   29066
Cards
Entrez_Gene (NCBI)GPATCH8  23131  G-patch domain containing 8
AliasesGPATC8; KIAA0553
GeneCards (Weizmann)GPATCH8
Ensembl hg19 (Hinxton)ENSG00000186566 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000186566 [Gene_View]  chr17:44395277-44503602 [Contig_View]  GPATCH8 [Vega]
ICGC DataPortalENSG00000186566
TCGA cBioPortalGPATCH8
AceView (NCBI)GPATCH8
Genatlas (Paris)GPATCH8
WikiGenes23131
SOURCE (Princeton)GPATCH8
Genetics Home Reference (NIH)GPATCH8
Genomic and cartography
GoldenPath hg38 (UCSC)GPATCH8  -     chr17:44395277-44503602 -  17q21.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GPATCH8  -     17q21.31   [Description]    (hg19-Feb_2009)
EnsemblGPATCH8 - 17q21.31 [CytoView hg19]  GPATCH8 - 17q21.31 [CytoView hg38]
Mapping of homologs : NCBIGPATCH8 [Mapview hg19]  GPATCH8 [Mapview hg38]
OMIM614396   
Gene and transcription
Genbank (Entrez)AB011125 AK025600 BC017808 BC024147 BC063601
RefSeq transcript (Entrez)NM_001002909 NM_001304939 NM_001304940 NM_001304941 NM_001304942 NM_001304943
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GPATCH8
Cluster EST : UnigeneHs.463129 [ NCBI ]
CGAP (NCI)Hs.463129
Alternative Splicing GalleryENSG00000186566
Gene ExpressionGPATCH8 [ NCBI-GEO ]   GPATCH8 [ EBI - ARRAY_EXPRESS ]   GPATCH8 [ SEEK ]   GPATCH8 [ MEM ]
Gene Expression Viewer (FireBrowse)GPATCH8 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23131
GTEX Portal (Tissue expression)GPATCH8
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UKJ3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UKJ3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UKJ3
Splice isoforms : SwissVarQ9UKJ3
PhosPhoSitePlusQ9UKJ3
Domaine pattern : Prosite (Expaxy)G_PATCH (PS50174)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)G_patch_dom    Znf_C2H2    Znf_C2H2_jaz   
Domain families : Pfam (Sanger)G-patch (PF01585)    zf-C2H2_jaz (PF12171)   
Domain families : Pfam (NCBI)pfam01585    pfam12171   
Domain families : Smart (EMBL)G_patch (SM00443)  
Conserved Domain (NCBI)GPATCH8
DMDM Disease mutations23131
Blocks (Seattle)GPATCH8
SuperfamilyQ9UKJ3
Human Protein AtlasENSG00000186566
Peptide AtlasQ9UKJ3
HPRD11089
IPIIPI00457284   IPI00942874   IPI00941748   IPI01018988   
Protein Interaction databases
DIP (DOE-UCLA)Q9UKJ3
IntAct (EBI)Q9UKJ3
FunCoupENSG00000186566
BioGRIDGPATCH8
STRING (EMBL)GPATCH8
ZODIACGPATCH8
Ontologies - Pathways
QuickGOQ9UKJ3
Ontology : AmiGORNA binding  protein binding  cellular_component  biological_process  metal ion binding  
Ontology : EGO-EBIRNA binding  protein binding  cellular_component  biological_process  metal ion binding  
NDEx NetworkGPATCH8
Atlas of Cancer Signalling NetworkGPATCH8
Wikipedia pathwaysGPATCH8
Orthology - Evolution
OrthoDB23131
GeneTree (enSembl)ENSG00000186566
Phylogenetic Trees/Animal Genes : TreeFamGPATCH8
HOVERGENQ9UKJ3
HOGENOMQ9UKJ3
Homologs : HomoloGeneGPATCH8
Homology/Alignments : Family Browser (UCSC)GPATCH8
Gene fusions - Rearrangements
Fusion : MitelmanDHX8/GPATCH8 [17q21.31/17q21.31]  [t(17;17)(q21;q21)]  
Fusion : MitelmanGPATCH8/C8orf46 [17q21.31/8q13.1]  [t(8;17)(q13;q21)]  
Fusion : MitelmanGPATCH8/COMTD1 [17q21.31/10q22.2]  [t(10;17)(q22;q21)]  
Fusion : MitelmanGPATCH8/MYO1D [17q21.31/17q11.2]  [t(17;17)(q11;q21)]  
Fusion : MitelmanGPATCH8/NPLOC4 [17q21.31/17q25.3]  [t(17;17)(q21;q25)]  
Fusion : MitelmanGPATCH8/ZMYM4 [17q21.31/1p34.3]  [t(1;17)(p34;q21)]  
Fusion : MitelmanRLF/GPATCH8 [1p34.2/17q21.31]  [t(1;17)(p34;q21)]  
Fusion : MitelmanTMEM132E/GPATCH8 [17q12/17q21.31]  [t(17;17)(q12;q21)]  
Fusion : MitelmanTMEM98/GPATCH8 [17q11.2/17q21.31]  [t(17;17)(q11;q21)]  
Fusion: TCGADHX8 17q21.31 GPATCH8 17q21.31 LUAD
Fusion: TCGAGPATCH8 17q21.31 COMTD1 10q22.2 PRAD
Fusion: TCGAGPATCH8 17q21.31 MYO1D 17q11.2 OV
Fusion: TCGAGPATCH8 17q21.31 NPLOC4 17q25.3 BRCA
Fusion: TCGAGPATCH8 17q21.31 ZMYM4 1p34.3 KIRC
Fusion: TCGARLF 1p34.2 GPATCH8 17q21.31 PRAD
Fusion: TCGATMEM132E 17q12 GPATCH8 17q21.31 BRCA
Fusion: TCGATMEM98 17q11.2 GPATCH8 17q21.31 LUSC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGPATCH8 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GPATCH8
dbVarGPATCH8
ClinVarGPATCH8
1000_GenomesGPATCH8 
Exome Variant ServerGPATCH8
ExAC (Exome Aggregation Consortium)GPATCH8 (select the gene name)
Genetic variants : HAPMAP23131
Genomic Variants (DGV)GPATCH8 [DGVbeta]
DECIPHERGPATCH8 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGPATCH8 
Mutations
ICGC Data PortalGPATCH8 
TCGA Data PortalGPATCH8 
Broad Tumor PortalGPATCH8
OASIS PortalGPATCH8 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGPATCH8  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGPATCH8
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GPATCH8
DgiDB (Drug Gene Interaction Database)GPATCH8
DoCM (Curated mutations)GPATCH8 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GPATCH8 (select a term)
intoGenGPATCH8
Cancer3DGPATCH8(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614396   
Orphanet
MedgenGPATCH8
Genetic Testing Registry GPATCH8
NextProtQ9UKJ3 [Medical]
TSGene23131
GENETestsGPATCH8
Target ValidationGPATCH8
Huge Navigator GPATCH8 [HugePedia]
snp3D : Map Gene to Disease23131
BioCentury BCIQGPATCH8
ClinGenGPATCH8
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23131
Chemical/Pharm GKB GenePA162390105
Clinical trialGPATCH8
Miscellaneous
canSAR (ICR)GPATCH8 (select the gene name)
Probes
Litterature
PubMed30 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGPATCH8
EVEXGPATCH8
GoPubMedGPATCH8
iHOPGPATCH8
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 1 17:02:19 CEST 2017

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