GPCPD1 (glycerophosphocholine phosphodiesterase 1)

2015-08-01  

Identity

HGNC
LOCATION
20p12.3
LOCUSID
ALIAS
EDI3,GDE5,GDPD6,PREI4
FUSION GENES

Other Information

Locus ID:

NCBI: 56261
MIM: 614124
HGNC: 26957
Ensembl: ENSG00000125772

Variants:

dbSNP: 56261
ClinVar: 56261
TCGA: ENSG00000125772
COSMIC: GPCPD1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000125772ENST00000379019Q9NPB8
ENSG00000125772ENST00000418646H0Y565
ENSG00000125772ENST00000481690A0A0J9YY12
ENSG00000125772ENST00000633552A0A0J9YVP8

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Pathways

PathwaySourceExternal ID
Glycerophospholipid metabolismKEGGko00564
Glycerophospholipid metabolismKEGGhsa00564
Choline metabolism in cancerKEGGhsa05231
Choline metabolism in cancerKEGGko05231
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Phospholipid metabolismREACTOMER-HSA-1483257
Glycerophospholipid biosynthesisREACTOMER-HSA-1483206
Hydrolysis of LPEREACTOMER-HSA-1483152
Hydrolysis of LPCREACTOMER-HSA-1483115

References

Pubmed IDYearTitleCitations
225705032012Choline-releasing glycerophosphodiesterase EDI3 drives tumor cell migration and metastasis.46
223432852012Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans.26
254825272014EDI3 links choline metabolism to integrin expression, cell adhesion and spreading.13

Citation

Dessen P

GPCPD1 (glycerophosphocholine phosphodiesterase 1)

Atlas Genet Cytogenet Oncol Haematol. 2015-08-01

Online version: http://atlasgeneticsoncology.org/gene/55316/gpcpd1