Identity
HGNC
LOCATION
12q13.12
LOCUSID
ALIAS
GPD-C,GPDH-C,HTGTI
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2819
MIM: 138420
HGNC: 4455
Ensembl: ENSG00000167588
Variants:
dbSNP: 2819
ClinVar: 2819
TCGA: ENSG00000167588
COSMIC: GPD1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000167588 | ENST00000301149 | P21695 |
| ENSG00000167588 | ENST00000301149 | A0A024R138 |
| ENSG00000167588 | ENST00000547964 | F8VSE8 |
| ENSG00000167588 | ENST00000548814 | P21695 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36632231 | 2023 | Non-bioenergetic roles of mitochondrial GPD2 promote tumor progression. | 3 |
| 36632231 | 2023 | Non-bioenergetic roles of mitochondrial GPD2 promote tumor progression. | 3 |
| 34657876 | 2022 | Decreased serum levels of glycerol-3- phosphate dehydrogenase 1 and monoacylglycerol lipase act as diagnostic biomarkers for breast cancer. | 3 |
| 34657876 | 2022 | Decreased serum levels of glycerol-3- phosphate dehydrogenase 1 and monoacylglycerol lipase act as diagnostic biomarkers for breast cancer. | 3 |
| 34098990 | 2021 | A HIF1α-GPD1 feedforward loop inhibits the progression of renal clear cell carcinoma via mitochondrial function and lipid metabolism. | 22 |
| 34098990 | 2021 | A HIF1α-GPD1 feedforward loop inhibits the progression of renal clear cell carcinoma via mitochondrial function and lipid metabolism. | 22 |
| 32250105 | 2020 | The Organization of Active Site Side Chains of Glycerol-3-phosphate Dehydrogenase Promotes Efficient Enzyme Catalysis and Rescue of Variant Enzymes. | 8 |
| 33120465 | 2020 | [Transient infantile hypertriglyceridemia caused by GPD1 deficiency: report of two cases and literature review]. | 2 |
| 32250105 | 2020 | The Organization of Active Site Side Chains of Glycerol-3-phosphate Dehydrogenase Promotes Efficient Enzyme Catalysis and Rescue of Variant Enzymes. | 8 |
| 33120465 | 2020 | [Transient infantile hypertriglyceridemia caused by GPD1 deficiency: report of two cases and literature review]. | 2 |
| 31467232 | 2019 | Comparative Proteome Analysis of Breast Cancer Tissues Highlights the Importance of Glycerol-3-phosphate Dehydrogenase 1 and Monoacylglycerol Lipase in Breast Cancer Metabolism. | 14 |
| 31467232 | 2019 | Comparative Proteome Analysis of Breast Cancer Tissues Highlights the Importance of Glycerol-3-phosphate Dehydrogenase 1 and Monoacylglycerol Lipase in Breast Cancer Metabolism. | 14 |
| 29927590 | 2018 | Primary Deuterium Kinetic Isotope Effects: A Probe for the Origin of the Rate Acceleration for Hydride Transfer Catalyzed by Glycerol-3-Phosphate Dehydrogenase. | 9 |
| 29927590 | 2018 | Primary Deuterium Kinetic Isotope Effects: A Probe for the Origin of the Rate Acceleration for Hydride Transfer Catalyzed by Glycerol-3-Phosphate Dehydrogenase. | 9 |
| 27368975 | 2016 | Expanding the molecular diversity and phenotypic spectrum of glycerol 3-phosphate dehydrogenase 1 deficiency. | 9 |
Citation
Dessen P
GPD1 (glycerol-3-phosphate dehydrogenase 1)
Atlas Genet Cytogenet Oncol Haematol. 2009-08-01
Online version: http://atlasgeneticsoncology.org/gene/51019/gpd1
