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GPD1 (glycerol-3-phosphate dehydrogenase 1)

Identity

Alias_namesglycerol-3-phosphate dehydrogenase 1 (soluble)
Other aliasGPD-C
GPDH-C
HTGTI
HGNC (Hugo) GPD1
LocusID (NCBI) 2819
Atlas_Id 51019
Location 12q13.12  [Link to chromosome band 12q13]
Location_base_pair Starts at 50497602 and ends at 50505103 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
GPD1 (12q13.12) / GPD1 (12q13.12)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GPD1   4455
Cards
Entrez_Gene (NCBI)GPD1  2819  glycerol-3-phosphate dehydrogenase 1
AliasesGPD-C; GPDH-C; HTGTI
GeneCards (Weizmann)GPD1
Ensembl hg19 (Hinxton)ENSG00000167588 [Gene_View]  chr12:50497602-50505103 [Contig_View]  GPD1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000167588 [Gene_View]  chr12:50497602-50505103 [Contig_View]  GPD1 [Vega]
ICGC DataPortalENSG00000167588
TCGA cBioPortalGPD1
AceView (NCBI)GPD1
Genatlas (Paris)GPD1
WikiGenes2819
SOURCE (Princeton)GPD1
Genetics Home Reference (NIH)GPD1
Genomic and cartography
GoldenPath hg19 (UCSC)GPD1  -     chr12:50497602-50505103 +  12q13.12   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)GPD1  -     12q13.12   [Description]    (hg38-Dec_2013)
EnsemblGPD1 - 12q13.12 [CytoView hg19]  GPD1 - 12q13.12 [CytoView hg38]
Mapping of homologs : NCBIGPD1 [Mapview hg19]  GPD1 [Mapview hg38]
OMIM138420   614480   
Gene and transcription
Genbank (Entrez)AI245302 AK130162 AK295911 AK312516 BC017429
RefSeq transcript (Entrez)NM_001257199 NM_005276
RefSeq genomic (Entrez)NC_000012 NC_018923 NG_032168 NT_029419 NW_004929384
Consensus coding sequences : CCDS (NCBI)GPD1
Cluster EST : UnigeneHs.524418 [ NCBI ]
CGAP (NCI)Hs.524418
Alternative Splicing GalleryENSG00000167588
Gene ExpressionGPD1 [ NCBI-GEO ]   GPD1 [ EBI - ARRAY_EXPRESS ]   GPD1 [ SEEK ]   GPD1 [ MEM ]
Gene Expression Viewer (FireBrowse)GPD1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2819
GTEX Portal (Tissue expression)GPD1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP21695   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP21695  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP21695
Splice isoforms : SwissVarP21695
PhosPhoSitePlusP21695
Domaine pattern : Prosite (Expaxy)NAD_G3PDH (PS00957)   
Domains : Interpro (EBI)6-PGluconate_DH_C-like    6PGD_dom_2    G3P_DH_NAD-dep    G3P_DH_NAD-dep_C    G3P_DH_NAD-dep_euk    G3P_DH_NAD-dep_N    NAD(P)-bd_dom   
Domain families : Pfam (Sanger)NAD_Gly3P_dh_C (PF07479)    NAD_Gly3P_dh_N (PF01210)   
Domain families : Pfam (NCBI)pfam07479    pfam01210   
Conserved Domain (NCBI)GPD1
DMDM Disease mutations2819
Blocks (Seattle)GPD1
PDB (SRS)1WPQ    1X0V    1X0X   
PDB (PDBSum)1WPQ    1X0V    1X0X   
PDB (IMB)1WPQ    1X0V    1X0X   
PDB (RSDB)1WPQ    1X0V    1X0X   
Structural Biology KnowledgeBase1WPQ    1X0V    1X0X   
SCOP (Structural Classification of Proteins)1WPQ    1X0V    1X0X   
CATH (Classification of proteins structures)1WPQ    1X0V    1X0X   
SuperfamilyP21695
Human Protein AtlasENSG00000167588
Peptide AtlasP21695
HPRD00714
IPIIPI00295777   IPI00011894   IPI01020783   IPI01020910   IPI01022917   
Protein Interaction databases
DIP (DOE-UCLA)P21695
IntAct (EBI)P21695
FunCoupENSG00000167588
BioGRIDGPD1
STRING (EMBL)GPD1
ZODIACGPD1
Ontologies - Pathways
QuickGOP21695
Ontology : AmiGOglycerol-3-phosphate dehydrogenase [NAD+] activity  glycerol-3-phosphate dehydrogenase activity  mitochondrion  cytosol  gluconeogenesis  glycerophosphate shuttle  phosphatidic acid biosynthetic process  glycerol-3-phosphate dehydrogenase complex  triglyceride biosynthetic process  protein homodimerization activity  positive regulation of glycolytic process  glycerol-3-phosphate catabolic process  NAD binding  extracellular exosome  cellular response to cAMP  cellular response to tumor necrosis factor  
Ontology : EGO-EBIglycerol-3-phosphate dehydrogenase [NAD+] activity  glycerol-3-phosphate dehydrogenase activity  mitochondrion  cytosol  gluconeogenesis  glycerophosphate shuttle  phosphatidic acid biosynthetic process  glycerol-3-phosphate dehydrogenase complex  triglyceride biosynthetic process  protein homodimerization activity  positive regulation of glycolytic process  glycerol-3-phosphate catabolic process  NAD binding  extracellular exosome  cellular response to cAMP  cellular response to tumor necrosis factor  
Pathways : KEGGGlycerophospholipid metabolism   
NDEx NetworkGPD1
Atlas of Cancer Signalling NetworkGPD1
Wikipedia pathwaysGPD1
Orthology - Evolution
OrthoDB2819
GeneTree (enSembl)ENSG00000167588
Phylogenetic Trees/Animal Genes : TreeFamGPD1
HOVERGENP21695
HOGENOMP21695
Homologs : HomoloGeneGPD1
Homology/Alignments : Family Browser (UCSC)GPD1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGPD1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GPD1
dbVarGPD1
ClinVarGPD1
1000_GenomesGPD1 
Exome Variant ServerGPD1
ExAC (Exome Aggregation Consortium)GPD1 (select the gene name)
Genetic variants : HAPMAP2819
Genomic Variants (DGV)GPD1 [DGVbeta]
DECIPHER (Syndromes)12:50497602-50505103  ENSG00000167588
CONAN: Copy Number AnalysisGPD1 
Mutations
ICGC Data PortalGPD1 
TCGA Data PortalGPD1 
Broad Tumor PortalGPD1
OASIS PortalGPD1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGPD1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGPD1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch GPD1
DgiDB (Drug Gene Interaction Database)GPD1
DoCM (Curated mutations)GPD1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GPD1 (select a term)
intoGenGPD1
Cancer3DGPD1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM138420    614480   
Orphanet21105   
MedgenGPD1
Genetic Testing Registry GPD1
NextProtP21695 [Medical]
TSGene2819
GENETestsGPD1
Huge Navigator GPD1 [HugePedia]
snp3D : Map Gene to Disease2819
BioCentury BCIQGPD1
ClinGenGPD1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2819
Chemical/Pharm GKB GenePA28836
Clinical trialGPD1
Miscellaneous
canSAR (ICR)GPD1 (select the gene name)
Probes
Litterature
PubMed26 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGPD1
EVEXGPD1
GoPubMedGPD1
iHOPGPD1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Tue Mar 14 13:07:58 CET 2017

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