Atlas of Genetics and Cytogenetics in Oncology and Haematology


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GPHB5 (glycoprotein hormone beta 5)

Identity

Alias_symbol (synonym)ZLUT1
GPB5
Other aliasB5
HGNC (Hugo) GPHB5
LocusID (NCBI) 122876
Atlas_Id 63936
Location 14q23.2  [Link to chromosome band 14q23]
Location_base_pair Starts at 63312835 and ends at 63318879 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GPHB5   18055
Cards
Entrez_Gene (NCBI)GPHB5  122876  glycoprotein hormone beta 5
AliasesB5; GPB5; ZLUT1
GeneCards (Weizmann)GPHB5
Ensembl hg19 (Hinxton)ENSG00000179600 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000179600 [Gene_View]  chr14:63312835-63318879 [Contig_View]  GPHB5 [Vega]
ICGC DataPortalENSG00000179600
TCGA cBioPortalGPHB5
AceView (NCBI)GPHB5
Genatlas (Paris)GPHB5
WikiGenes122876
SOURCE (Princeton)GPHB5
Genetics Home Reference (NIH)GPHB5
Genomic and cartography
GoldenPath hg38 (UCSC)GPHB5  -     chr14:63312835-63318879 -  14q23.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GPHB5  -     14q23.2   [Description]    (hg19-Feb_2009)
EnsemblGPHB5 - 14q23.2 [CytoView hg19]  GPHB5 - 14q23.2 [CytoView hg38]
Mapping of homologs : NCBIGPHB5 [Mapview hg19]  GPHB5 [Mapview hg38]
OMIM609652   
Gene and transcription
Genbank (Entrez)AF403430 AF467770 BC069113 BC133702 BM709443
RefSeq transcript (Entrez)NM_145171
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GPHB5
Cluster EST : UnigeneHs.375028 [ NCBI ]
CGAP (NCI)Hs.375028
Alternative Splicing GalleryENSG00000179600
Gene ExpressionGPHB5 [ NCBI-GEO ]   GPHB5 [ EBI - ARRAY_EXPRESS ]   GPHB5 [ SEEK ]   GPHB5 [ MEM ]
Gene Expression Viewer (FireBrowse)GPHB5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)122876
GTEX Portal (Tissue expression)GPHB5
Human Protein AtlasENSG00000179600-GPHB5 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86YW7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86YW7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86YW7
Splice isoforms : SwissVarQ86YW7
PhosPhoSitePlusQ86YW7
Domains : Interpro (EBI)Cystine-knot_cytokine    Glyco_hormone_CN    Gonadotropin_bsu   
Domain families : Pfam (Sanger)Cys_knot (PF00007)   
Domain families : Pfam (NCBI)pfam00007   
Domain families : Smart (EMBL)GHB (SM00068)  
Conserved Domain (NCBI)GPHB5
DMDM Disease mutations122876
Blocks (Seattle)GPHB5
SuperfamilyQ86YW7
Human Protein Atlas [tissue]ENSG00000179600-GPHB5 [tissue]
Peptide AtlasQ86YW7
HPRD17053
IPIIPI00168925   
Protein Interaction databases
DIP (DOE-UCLA)Q86YW7
IntAct (EBI)Q86YW7
FunCoupENSG00000179600
BioGRIDGPHB5
STRING (EMBL)GPHB5
ZODIACGPHB5
Ontologies - Pathways
QuickGOQ86YW7
Ontology : AmiGOregulation of thyroid hormone mediated signaling pathway  hormone activity  extracellular region  extracellular space  cytoplasm  cell surface receptor signaling pathway  G-protein coupled receptor signaling pathway  cell-cell signaling  hormone-mediated signaling pathway  positive regulation of cAMP biosynthetic process  thyrotropin-releasing hormone receptor binding  protein heterodimerization activity  
Ontology : EGO-EBIregulation of thyroid hormone mediated signaling pathway  hormone activity  extracellular region  extracellular space  cytoplasm  cell surface receptor signaling pathway  G-protein coupled receptor signaling pathway  cell-cell signaling  hormone-mediated signaling pathway  positive regulation of cAMP biosynthetic process  thyrotropin-releasing hormone receptor binding  protein heterodimerization activity  
NDEx NetworkGPHB5
Atlas of Cancer Signalling NetworkGPHB5
Wikipedia pathwaysGPHB5
Orthology - Evolution
OrthoDB122876
GeneTree (enSembl)ENSG00000179600
Phylogenetic Trees/Animal Genes : TreeFamGPHB5
HOVERGENQ86YW7
HOGENOMQ86YW7
Homologs : HomoloGeneGPHB5
Homology/Alignments : Family Browser (UCSC)GPHB5
Gene fusions - Rearrangements
Fusion: Tumor Portal GPHB5
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGPHB5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GPHB5
dbVarGPHB5
ClinVarGPHB5
1000_GenomesGPHB5 
Exome Variant ServerGPHB5
ExAC (Exome Aggregation Consortium)ENSG00000179600
GNOMAD BrowserENSG00000179600
Genetic variants : HAPMAP122876
Genomic Variants (DGV)GPHB5 [DGVbeta]
DECIPHERGPHB5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGPHB5 
Mutations
ICGC Data PortalGPHB5 
TCGA Data PortalGPHB5 
Broad Tumor PortalGPHB5
OASIS PortalGPHB5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGPHB5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGPHB5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GPHB5
DgiDB (Drug Gene Interaction Database)GPHB5
DoCM (Curated mutations)GPHB5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GPHB5 (select a term)
intoGenGPHB5
Cancer3DGPHB5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609652   
Orphanet
MedgenGPHB5
Genetic Testing Registry GPHB5
NextProtQ86YW7 [Medical]
TSGene122876
GENETestsGPHB5
Target ValidationGPHB5
Huge Navigator GPHB5 [HugePedia]
snp3D : Map Gene to Disease122876
BioCentury BCIQGPHB5
ClinGenGPHB5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD122876
Chemical/Pharm GKB GenePA134872371
Clinical trialGPHB5
Miscellaneous
canSAR (ICR)GPHB5 (select the gene name)
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGPHB5
EVEXGPHB5
GoPubMedGPHB5
iHOPGPHB5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Nov 9 11:49:28 CET 2017

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