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GPI (glucose-6-phosphate isomerase)

Identity

Other namesAMF
GNPI
NLK
PGI
PHI
SA-36
SA36
HGNC (Hugo) GPI
LocusID (NCBI) 2821
Location 19q13.11
Location_base_pair Starts at 34856032 and ends at 34893318 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)GPI   4458
Cards
Entrez_Gene (NCBI)GPI  2821  glucose-6-phosphate isomerase
GeneCards (Weizmann)GPI
Ensembl (Hinxton)ENSG00000105220 [Gene_View]  chr19:34856032-34893318 [Contig_View]  GPI [Vega]
ICGC DataPortalENSG00000105220
AceView (NCBI)GPI
Genatlas (Paris)GPI
WikiGenes2821
SOURCE (Princeton)NM_000175 NM_001184722 NM_001289789 NM_001289790
Genomic and cartography
GoldenPath (UCSC)GPI  -  19q13.11   chr19:34856032-34893318 +  19q13.11   [Description]    (hg19-Feb_2009)
EnsemblGPI - 19q13.11 [CytoView]
Mapping of homologs : NCBIGPI [Mapview]
OMIM172400   613470   
Gene and transcription
Genbank (Entrez)AB209575 AK025421 AK129884 AK130102 AK293446
RefSeq transcript (Entrez)NM_000175 NM_001184722 NM_001289789 NM_001289790
RefSeq genomic (Entrez)AC_000151 NC_000019 NC_018930 NG_012838 NT_011109 NT_187619 NW_001838493 NW_001838494 NW_004929415
Consensus coding sequences : CCDS (NCBI)GPI
Cluster EST : UnigeneHs.515344 [ NCBI ]
CGAP (NCI)Hs.515344
Alternative Splicing : Fast-db (Paris)GSHG0014803
Alternative Splicing GalleryENSG00000105220
Gene ExpressionGPI [ NCBI-GEO ]     GPI [ SEEK ]   GPI [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP06744 (Uniprot)
NextProtP06744  [Medical]
With graphics : InterProP06744
Splice isoforms : SwissVarP06744 (Swissvar)
Catalytic activity : Enzyme5.3.1.9 [ Enzyme-Expasy ]   5.3.1.95.3.1.9 [ IntEnz-EBI ]   5.3.1.9 [ BRENDA ]   5.3.1.9 [ KEGG ]   
Domaine pattern : Prosite (Expaxy)P_GLUCOSE_ISOMERASE_1 (PS00765)    P_GLUCOSE_ISOMERASE_2 (PS00174)    P_GLUCOSE_ISOMERASE_3 (PS51463)   
Domains : Interpro (EBI)G6P_Isomerase    G6P_Isomerase_C    Phosphoglucose_isomerase_CS   
Related proteins : CluSTrP06744
Domain families : Pfam (Sanger)PGI (PF00342)   
Domain families : Pfam (NCBI)pfam00342   
DMDM Disease mutations2821
Blocks (Seattle)P06744
PDB (SRS)1IAT    1IRI    1JIQ    1JLH    1NUH   
PDB (PDBSum)1IAT    1IRI    1JIQ    1JLH    1NUH   
PDB (IMB)1IAT    1IRI    1JIQ    1JLH    1NUH   
PDB (RSDB)1IAT    1IRI    1JIQ    1JLH    1NUH   
Human Protein AtlasENSG00000105220
Peptide AtlasP06744
HPRD01394
IPIIPI00027497   IPI00908881   IPI00556013   IPI00910781   
Protein Interaction databases
DIP (DOE-UCLA)P06744
IntAct (EBI)P06744
FunCoupENSG00000105220
BioGRIDGPI
InParanoidP06744
Interologous Interaction database P06744
IntegromeDBGPI
STRING (EMBL)GPI
Ontologies - Pathways
Ontology : AmiGOangiogenesis  glucose-6-phosphate isomerase activity  cytokine activity  extracellular space  nucleus  nucleolus  cytoplasm  cytosol  plasma membrane  carbohydrate metabolic process  glucose metabolic process  gluconeogenesis  glycolytic process  glycolytic process  humoral immune response  hemostasis  learning or memory  growth factor activity  membrane  intramolecular transferase activity  methylglyoxal biosynthetic process  neuron projection  negative regulation of cysteine-type endopeptidase activity involved in apoptotic process  negative regulation of neuron apoptotic process  small molecule metabolic process  aldehyde catabolic process  monosaccharide binding  glucose 6-phosphate metabolic process  extracellular vesicular exosome  
Ontology : EGO-EBIangiogenesis  glucose-6-phosphate isomerase activity  cytokine activity  extracellular space  nucleus  nucleolus  cytoplasm  cytosol  plasma membrane  carbohydrate metabolic process  glucose metabolic process  gluconeogenesis  glycolytic process  glycolytic process  humoral immune response  hemostasis  learning or memory  growth factor activity  membrane  intramolecular transferase activity  methylglyoxal biosynthetic process  neuron projection  negative regulation of cysteine-type endopeptidase activity involved in apoptotic process  negative regulation of neuron apoptotic process  small molecule metabolic process  aldehyde catabolic process  monosaccharide binding  glucose 6-phosphate metabolic process  extracellular vesicular exosome  
Pathways : BIOCARTAGlycolysis Pathway [Genes]   
Pathways : KEGGGlycolysis / Gluconeogenesis    Pentose phosphate pathway    Starch and sucrose metabolism    Amino sugar and nucleotide sugar metabolism   
Protein Interaction DatabaseGPI
Wikipedia pathwaysGPI
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)GPI
SNP (GeneSNP Utah)GPI
SNP : HGBaseGPI
Genetic variants : HAPMAPGPI
1000_GenomesGPI 
ICGC programENSG00000105220 
CONAN: Copy Number AnalysisGPI 
Somatic Mutations in Cancer : COSMICGPI 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Mutations and Diseases : HGMDGPI
OMIM172400    613470   
MedgenGPI
GENETestsGPI
Disease Genetic AssociationGPI
Huge Navigator GPI [HugePedia]  GPI [HugeCancerGEM]
Genomic VariantsGPI  GPI [DGVbeta]
Exome VariantGPI
dbVarGPI
ClinVarGPI
snp3D : Map Gene to Disease2821
General knowledge
Homologs : HomoloGeneGPI
Homology/Alignments : Family Browser (UCSC)GPI
Phylogenetic Trees/Animal Genes : TreeFamGPI
Chemical/Protein Interactions : CTD2821
Chemical/Pharm GKB GenePA28841
Clinical trialGPI
Cancer Resource (Charite)ENSG00000105220
Other databases
Probes
Litterature
PubMed96 Pubmed reference(s) in Entrez
CoreMineGPI
iHOPGPI
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 13 12:48:59 CEST 2014

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