Atlas of Genetics and Cytogenetics in Oncology and Haematology


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GPM6A (glycoprotein M6A)

Identity

Alias_namesGPM6
Other aliasM6A
HGNC (Hugo) GPM6A
LocusID (NCBI) 2823
Atlas_Id 55189
Location 4q34.2  [Link to chromosome band 4q34]
Location_base_pair Starts at 176554088 and ends at 176923842 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
FUBP1 (1p31.1) / GPM6A (4q34.2)GPM6A (4q34.2) / ANKRD17 (4q13.3)GPM6A (4q34.2) / BRWD1 (21q22.2)
GPM6A (4q34.2) / HPX (11p15.4)GPM6A (4q34.2) / POLR2A (17p13.1)GPM6A (4q34.2) / SCLT1 (4q28.2)
GUCY1A3 (4q32.1) / GPM6A (4q34.2)TMBIM6 (12q13.12) / GPM6A (4q34.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GPM6A   4460
Cards
Entrez_Gene (NCBI)GPM6A  2823  glycoprotein M6A
AliasesGPM6; M6A
GeneCards (Weizmann)GPM6A
Ensembl hg19 (Hinxton)ENSG00000150625 [Gene_View]  chr4:176554088-176923842 [Contig_View]  GPM6A [Vega]
Ensembl hg38 (Hinxton)ENSG00000150625 [Gene_View]  chr4:176554088-176923842 [Contig_View]  GPM6A [Vega]
ICGC DataPortalENSG00000150625
TCGA cBioPortalGPM6A
AceView (NCBI)GPM6A
Genatlas (Paris)GPM6A
WikiGenes2823
SOURCE (Princeton)GPM6A
Genetics Home Reference (NIH)GPM6A
Genomic and cartography
GoldenPath hg19 (UCSC)GPM6A  -     chr4:176554088-176923842 -  4q34.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)GPM6A  -     4q34.2   [Description]    (hg38-Dec_2013)
EnsemblGPM6A - 4q34.2 [CytoView hg19]  GPM6A - 4q34.2 [CytoView hg38]
Mapping of homologs : NCBIGPM6A [Mapview hg19]  GPM6A [Mapview hg38]
OMIM601275   
Gene and transcription
Genbank (Entrez)AI609188 AK226176 AK299788 AX772804 BC010461
RefSeq transcript (Entrez)NM_001261447 NM_001261448 NM_005277 NM_201591 NM_201592
RefSeq genomic (Entrez)NC_000004 NC_018915 NT_016354 NW_004929320
Consensus coding sequences : CCDS (NCBI)GPM6A
Cluster EST : UnigeneHs.75819 [ NCBI ]
CGAP (NCI)Hs.75819
Alternative Splicing GalleryENSG00000150625
Gene ExpressionGPM6A [ NCBI-GEO ]   GPM6A [ EBI - ARRAY_EXPRESS ]   GPM6A [ SEEK ]   GPM6A [ MEM ]
Gene Expression Viewer (FireBrowse)GPM6A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2823
GTEX Portal (Tissue expression)GPM6A
Protein : pattern, domain, 3D structure
UniProt/SwissProtP51674   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP51674  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP51674
Splice isoforms : SwissVarP51674
PhosPhoSitePlusP51674
Domaine pattern : Prosite (Expaxy)MYELIN_PLP_1 (PS00575)    MYELIN_PLP_2 (PS01004)   
Domains : Interpro (EBI)Myelin_PLP    Myelin_PLP_CS   
Domain families : Pfam (Sanger)Myelin_PLP (PF01275)   
Domain families : Pfam (NCBI)pfam01275   
Domain families : Smart (EMBL)PLP (SM00002)  
Conserved Domain (NCBI)GPM6A
DMDM Disease mutations2823
Blocks (Seattle)GPM6A
SuperfamilyP51674
Human Protein AtlasENSG00000150625
Peptide AtlasP51674
HPRD03174
IPIIPI00019952   IPI00967359   IPI00965865   IPI00965250   IPI00964247   IPI00965292   IPI00977496   IPI00966268   IPI00964233   IPI00963915   IPI00967662   IPI00963902   IPI00966917   IPI00965239   IPI00966550   IPI00968213   IPI00967206   
Protein Interaction databases
DIP (DOE-UCLA)P51674
IntAct (EBI)P51674
FunCoupENSG00000150625
BioGRIDGPM6A
STRING (EMBL)GPM6A
ZODIACGPM6A
Ontologies - Pathways
QuickGOP51674
Ontology : AmiGOneuron migration  neural retina development  calcium channel activity  protein binding  plasma membrane  synapse assembly  integral component of membrane  filopodium  neuron projection  neuronal cell body  dendritic spine  axonal growth cone  neuron projection morphogenesis  stem cell differentiation  positive regulation of filopodium assembly  extracellular exosome  calcium ion transmembrane transport  extracellular vesicle  
Ontology : EGO-EBIneuron migration  neural retina development  calcium channel activity  protein binding  plasma membrane  synapse assembly  integral component of membrane  filopodium  neuron projection  neuronal cell body  dendritic spine  axonal growth cone  neuron projection morphogenesis  stem cell differentiation  positive regulation of filopodium assembly  extracellular exosome  calcium ion transmembrane transport  extracellular vesicle  
NDEx NetworkGPM6A
Atlas of Cancer Signalling NetworkGPM6A
Wikipedia pathwaysGPM6A
Orthology - Evolution
OrthoDB2823
GeneTree (enSembl)ENSG00000150625
Phylogenetic Trees/Animal Genes : TreeFamGPM6A
HOVERGENP51674
HOGENOMP51674
Homologs : HomoloGeneGPM6A
Homology/Alignments : Family Browser (UCSC)GPM6A
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGPM6A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GPM6A
dbVarGPM6A
ClinVarGPM6A
1000_GenomesGPM6A 
Exome Variant ServerGPM6A
ExAC (Exome Aggregation Consortium)GPM6A (select the gene name)
Genetic variants : HAPMAP2823
Genomic Variants (DGV)GPM6A [DGVbeta]
DECIPHER (Syndromes)4:176554088-176923842  ENSG00000150625
CONAN: Copy Number AnalysisGPM6A 
Mutations
ICGC Data PortalGPM6A 
TCGA Data PortalGPM6A 
Broad Tumor PortalGPM6A
OASIS PortalGPM6A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGPM6A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGPM6A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GPM6A
DgiDB (Drug Gene Interaction Database)GPM6A
DoCM (Curated mutations)GPM6A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GPM6A (select a term)
intoGenGPM6A
Cancer3DGPM6A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601275   
Orphanet
MedgenGPM6A
Genetic Testing Registry GPM6A
NextProtP51674 [Medical]
TSGene2823
GENETestsGPM6A
Huge Navigator GPM6A [HugePedia]
snp3D : Map Gene to Disease2823
BioCentury BCIQGPM6A
ClinGenGPM6A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2823
Chemical/Pharm GKB GenePA28843
Clinical trialGPM6A
Miscellaneous
canSAR (ICR)GPM6A (select the gene name)
Probes
Litterature
PubMed30 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGPM6A
EVEXGPM6A
GoPubMedGPM6A
iHOPGPM6A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:07:59 CET 2017

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