Atlas of Genetics and Cytogenetics in Oncology and Haematology


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GPM6B (glycoprotein M6B)

Identity

Alias_symbol (synonym)M6B
MGC17150
MGC54284
Other alias
HGNC (Hugo) GPM6B
LocusID (NCBI) 2824
Atlas_Id 54858
Location Xp22.2  [Link to chromosome band Xp22]
Location_base_pair Starts at 13770922 and ends at 13938824 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
GPM6B (Xp22.2) / ACTG1 (17q25.3)GPM6B (Xp22.2) / CHD1 (5q15)GPM6B (Xp22.2) / GPM6B (Xp22.2)
GPM6B (Xp22.2) / SLC26A2 (5q32)HIST1H2AM (6p22.1) / GPM6B (Xp22.2)PKNOX1 (21q22.3) / GPM6B (Xp22.2)
GPM6B Xp22.2 / CHD1 5q15

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GPM6B   4461
Cards
Entrez_Gene (NCBI)GPM6B  2824  glycoprotein M6B
AliasesM6B
GeneCards (Weizmann)GPM6B
Ensembl hg19 (Hinxton)ENSG00000046653 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000046653 [Gene_View]  chrX:13770922-13938824 [Contig_View]  GPM6B [Vega]
ICGC DataPortalENSG00000046653
TCGA cBioPortalGPM6B
AceView (NCBI)GPM6B
Genatlas (Paris)GPM6B
WikiGenes2824
SOURCE (Princeton)GPM6B
Genetics Home Reference (NIH)GPM6B
Genomic and cartography
GoldenPath hg38 (UCSC)GPM6B  -     chrX:13770922-13938824 -  Xp22.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GPM6B  -     Xp22.2   [Description]    (hg19-Feb_2009)
EnsemblGPM6B - Xp22.2 [CytoView hg19]  GPM6B - Xp22.2 [CytoView hg38]
Mapping of homologs : NCBIGPM6B [Mapview hg19]  GPM6B [Mapview hg38]
OMIM300051   
Gene and transcription
Genbank (Entrez)###############################################################################################################################################################################################################################################################
RefSeq transcript (Entrez)NM_001001994 NM_001001995 NM_001001996 NM_001318729 NM_005278
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GPM6B
Cluster EST : UnigeneHs.495710 [ NCBI ]
CGAP (NCI)Hs.495710
Alternative Splicing GalleryENSG00000046653
Gene ExpressionGPM6B [ NCBI-GEO ]   GPM6B [ EBI - ARRAY_EXPRESS ]   GPM6B [ SEEK ]   GPM6B [ MEM ]
Gene Expression Viewer (FireBrowse)GPM6B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2824
GTEX Portal (Tissue expression)GPM6B
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13491   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ13491  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ13491
Splice isoforms : SwissVarQ13491
PhosPhoSitePlusQ13491
Domaine pattern : Prosite (Expaxy)MYELIN_PLP_1 (PS00575)    MYELIN_PLP_2 (PS01004)   
Domains : Interpro (EBI)Myelin_PLP    Myelin_PLP_CS   
Domain families : Pfam (Sanger)Myelin_PLP (PF01275)   
Domain families : Pfam (NCBI)pfam01275   
Domain families : Smart (EMBL)PLP (SM00002)  
Conserved Domain (NCBI)GPM6B
DMDM Disease mutations2824
Blocks (Seattle)GPM6B
SuperfamilyQ13491
Human Protein AtlasENSG00000046653
Peptide AtlasQ13491
HPRD02082
IPIIPI00013421   IPI00411643   IPI00384484   IPI00187158   IPI00946649   IPI00945372   IPI00945898   IPI00945202   IPI00945561   IPI00946263   IPI00946093   
Protein Interaction databases
DIP (DOE-UCLA)Q13491
IntAct (EBI)Q13491
FunCoupENSG00000046653
BioGRIDGPM6B
STRING (EMBL)GPM6B
ZODIACGPM6B
Ontologies - Pathways
QuickGOQ13491
Ontology : AmiGOossification  molecular_function  plasma membrane  nervous system development  protein transport  integral component of membrane  cell differentiation  positive regulation of bone mineralization  regulation of actin cytoskeleton organization  membrane raft  negative regulation of serotonin uptake  regulation of focal adhesion assembly  extracellular matrix assembly  negative regulation of protein localization to cell surface  
Ontology : EGO-EBIossification  molecular_function  plasma membrane  nervous system development  protein transport  integral component of membrane  cell differentiation  positive regulation of bone mineralization  regulation of actin cytoskeleton organization  membrane raft  negative regulation of serotonin uptake  regulation of focal adhesion assembly  extracellular matrix assembly  negative regulation of protein localization to cell surface  
NDEx NetworkGPM6B
Atlas of Cancer Signalling NetworkGPM6B
Wikipedia pathwaysGPM6B
Orthology - Evolution
OrthoDB2824
GeneTree (enSembl)ENSG00000046653
Phylogenetic Trees/Animal Genes : TreeFamGPM6B
HOVERGENQ13491
HOGENOMQ13491
Homologs : HomoloGeneGPM6B
Homology/Alignments : Family Browser (UCSC)GPM6B
Gene fusions - Rearrangements
Fusion : MitelmanGPM6B/CHD1 [Xp22.2/5q15]  
Fusion: TCGAGPM6B Xp22.2 CHD1 5q15 LGG
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGPM6B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GPM6B
dbVarGPM6B
ClinVarGPM6B
1000_GenomesGPM6B 
Exome Variant ServerGPM6B
ExAC (Exome Aggregation Consortium)GPM6B (select the gene name)
Genetic variants : HAPMAP2824
Genomic Variants (DGV)GPM6B [DGVbeta]
DECIPHERGPM6B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGPM6B 
Mutations
ICGC Data PortalGPM6B 
TCGA Data PortalGPM6B 
Broad Tumor PortalGPM6B
OASIS PortalGPM6B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGPM6B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGPM6B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
LOVD (Leiden Open Variation Database)The Globin Gene Server
BioMutasearch GPM6B
DgiDB (Drug Gene Interaction Database)GPM6B
DoCM (Curated mutations)GPM6B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GPM6B (select a term)
intoGenGPM6B
Cancer3DGPM6B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300051   
Orphanet
MedgenGPM6B
Genetic Testing Registry GPM6B
NextProtQ13491 [Medical]
TSGene2824
GENETestsGPM6B
Target ValidationGPM6B
Huge Navigator GPM6B [HugePedia]
snp3D : Map Gene to Disease2824
BioCentury BCIQGPM6B
ClinGenGPM6B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2824
Chemical/Pharm GKB GenePA28844
Clinical trialGPM6B
Miscellaneous
canSAR (ICR)GPM6B (select the gene name)
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGPM6B
EVEXGPM6B
GoPubMedGPM6B
iHOPGPM6B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:35:48 CEST 2017

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