GPM6B (glycoprotein M6B)

2014-09-01  

Identity

HGNC
LOCATION
Xp22.2
LOCUSID
ALIAS
M6B
FUSION GENES

Other Information

Locus ID:

NCBI: 2824
MIM: 300051
HGNC: 4461
Ensembl: ENSG00000046653

Variants:

dbSNP: 2824
ClinVar: 2824
TCGA: ENSG00000046653
COSMIC: GPM6B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000046653ENST00000316715Q13491
ENSG00000046653ENST00000355135Q13491
ENSG00000046653ENST00000355135A0A024RBX1
ENSG00000046653ENST00000356942Q13491
ENSG00000046653ENST00000356942A0A024RBV7
ENSG00000046653ENST00000398361B7Z248
ENSG00000046653ENST00000454189Q13491
ENSG00000046653ENST00000468080C9JZE8
ENSG00000046653ENST00000475307C9J028
ENSG00000046653ENST00000493085C9J8H8
ENSG00000046653ENST00000493677B7Z613

Expression (GTEx)

0
100
200
300
400
500
600
700

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
216383162011GPM6B regulates osteoblast function and induction of mineralization by controlling cytoskeleton and matrix vesicle release.19
179182492008Fetal hemoglobin in sickle cell anemia: Bayesian modeling of genetic associations.14
185812702009Membrane glycoprotein M6B interacts with the human serotonin transporter.13
239508702013Discovery and validation of DNA hypomethylation biomarkers for liver cancer using HRM-specific probes.6
246965292014Breast carcinoma progression and tumour vascular markers related to apoptotic mechanisms.4
249169152014Identification of GPM6A and GPM6B as potential new human lymphoid leukemia-associated oncogenes.4
251132532014Vascular marker expression during the development of various types of gynaecological malignancy.3
164162652006PLP1 and GPM6B intragenic copy number analysis by MAPH in 262 patients with hypomyelinating leukodystrophies: Identification of one partial triplication and two partial deletions of PLP1.2
303725672019Glycoprotein M6B Interacts with TβRI to Activate TGF-β-Smad2/3 Signaling and Promote Smooth Muscle Cell Differentiation.2
152140072004Mutation analysis of the M6b gene in patients with Pelizaeus-Merzbacher-like syndrome.1

Citation

Dessen P

GPM6B (glycoprotein M6B)

Atlas Genet Cytogenet Oncol Haematol. 2014-09-01

Online version: http://atlasgeneticsoncology.org/gene/54858/gpm6b