GPR108 (G protein-coupled receptor 108)

2014-11-01  

Identity

HGNC
LOCATION
19p13.3
LOCUSID
ALIAS
LUSTR2
FUSION GENES

Other Information

Locus ID:

NCBI: 56927
MIM: 618491
HGNC: 17829
Ensembl: ENSG00000125734

Variants:

dbSNP: 56927
ClinVar: 56927
TCGA: ENSG00000125734
COSMIC: GPR108

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000125734ENST00000264080Q9NPR9
ENSG00000125734ENST00000430424G5E9L6
ENSG00000125734ENST00000594034M0QZW9
ENSG00000125734ENST00000594500M0R2E1
ENSG00000125734ENST00000595908M0QZY1
ENSG00000125734ENST00000597298M0QZ03
ENSG00000125734ENST00000597706M0R1G1
ENSG00000125734ENST00000598052M0R1Q3
ENSG00000125734ENST00000598955M0R3H4
ENSG00000125734ENST00000601716M0QYF6

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
194235402009Common variation in genes related to innate immunity and risk of adult glioma.19
204069642010Risk of meningioma and common variation in genes related to innate immunity.12
174540092007Human GPR107 and murine Gpr108 are members of the LUSTR family of proteins found in both plants and animals, having similar topology to G-protein coupled receptors.7
204387852010Polymorphisms in innate immunity genes and risk of childhood leukemia.5
303324312018GPR108, an NF-κB activator suppressed by TIRAP, negatively regulates TLR-triggered immune responses.3

Citation

Dessen P

GPR108 (G protein-coupled receptor 108)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/63944/gpr108