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GPR12 (G protein-coupled receptor 12)

Identity

Alias_namesregulatory subunit 84
Alias_symbol (synonym)GPCR21
PPP1R84
Other aliasGPCR12
HGNC (Hugo) GPR12
LocusID (NCBI) 2835
Atlas_Id 56043
Location 13q12.13  [Link to chromosome band 13q12]
Location_base_pair Starts at 26755201 and ends at 26760785 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GPR12   4466
Cards
Entrez_Gene (NCBI)GPR12  2835  G protein-coupled receptor 12
AliasesGPCR12; GPCR21; PPP1R84
GeneCards (Weizmann)GPR12
Ensembl hg19 (Hinxton)ENSG00000132975 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000132975 [Gene_View]  chr13:26755201-26760785 [Contig_View]  GPR12 [Vega]
ICGC DataPortalENSG00000132975
TCGA cBioPortalGPR12
AceView (NCBI)GPR12
Genatlas (Paris)GPR12
WikiGenes2835
SOURCE (Princeton)GPR12
Genetics Home Reference (NIH)GPR12
Genomic and cartography
GoldenPath hg38 (UCSC)GPR12  -     chr13:26755201-26760785 -  13q12.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GPR12  -     13q12.13   [Description]    (hg19-Feb_2009)
EnsemblGPR12 - 13q12.13 [CytoView hg19]  GPR12 - 13q12.13 [CytoView hg38]
Mapping of homologs : NCBIGPR12 [Mapview hg19]  GPR12 [Mapview hg38]
OMIM600752   
Gene and transcription
Genbank (Entrez)AK055229 AK290220 AK294378 AK307756 AK311107
RefSeq transcript (Entrez)NM_005288
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GPR12
Cluster EST : UnigeneHs.123034 [ NCBI ]
CGAP (NCI)Hs.123034
Alternative Splicing GalleryENSG00000132975
Gene ExpressionGPR12 [ NCBI-GEO ]   GPR12 [ EBI - ARRAY_EXPRESS ]   GPR12 [ SEEK ]   GPR12 [ MEM ]
Gene Expression Viewer (FireBrowse)GPR12 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2835
GTEX Portal (Tissue expression)GPR12
Protein : pattern, domain, 3D structure
UniProt/SwissProtP47775   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP47775  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP47775
Splice isoforms : SwissVarP47775
PhosPhoSitePlusP47775
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)GPCR_Rhodpsn    GPCR_Rhodpsn_7TM    GPR12    GPR_3/6/12_orphan   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Domain families : Smart (EMBL)7TM_GPCR_Srsx (SM01381)  
Conserved Domain (NCBI)GPR12
DMDM Disease mutations2835
Blocks (Seattle)GPR12
SuperfamilyP47775
Human Protein AtlasENSG00000132975
Peptide AtlasP47775
HPRD15978
IPIIPI00026228   
Protein Interaction databases
DIP (DOE-UCLA)P47775
IntAct (EBI)P47775
FunCoupENSG00000132975
BioGRIDGPR12
STRING (EMBL)GPR12
ZODIACGPR12
Ontologies - Pathways
QuickGOP47775
Ontology : AmiGOG-protein coupled receptor activity  integral component of plasma membrane  cellular calcium ion homeostasis  G-protein coupled receptor signaling pathway  phosphatidylcholine binding  
Ontology : EGO-EBIG-protein coupled receptor activity  integral component of plasma membrane  cellular calcium ion homeostasis  G-protein coupled receptor signaling pathway  phosphatidylcholine binding  
NDEx NetworkGPR12
Atlas of Cancer Signalling NetworkGPR12
Wikipedia pathwaysGPR12
Orthology - Evolution
OrthoDB2835
GeneTree (enSembl)ENSG00000132975
Phylogenetic Trees/Animal Genes : TreeFamGPR12
HOVERGENP47775
HOGENOMP47775
Homologs : HomoloGeneGPR12
Homology/Alignments : Family Browser (UCSC)GPR12
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGPR12 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GPR12
dbVarGPR12
ClinVarGPR12
1000_GenomesGPR12 
Exome Variant ServerGPR12
ExAC (Exome Aggregation Consortium)GPR12 (select the gene name)
Genetic variants : HAPMAP2835
Genomic Variants (DGV)GPR12 [DGVbeta]
DECIPHERGPR12 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGPR12 
Mutations
ICGC Data PortalGPR12 
TCGA Data PortalGPR12 
Broad Tumor PortalGPR12
OASIS PortalGPR12 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGPR12  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGPR12
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GPR12
DgiDB (Drug Gene Interaction Database)GPR12
DoCM (Curated mutations)GPR12 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GPR12 (select a term)
intoGenGPR12
Cancer3DGPR12(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600752   
Orphanet
MedgenGPR12
Genetic Testing Registry GPR12
NextProtP47775 [Medical]
TSGene2835
GENETestsGPR12
Target ValidationGPR12
Huge Navigator GPR12 [HugePedia]
snp3D : Map Gene to Disease2835
BioCentury BCIQGPR12
ClinGenGPR12
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2835
Chemical/Pharm GKB GenePA28856
Clinical trialGPR12
Miscellaneous
canSAR (ICR)GPR12 (select the gene name)
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGPR12
EVEXGPR12
GoPubMedGPR12
iHOPGPR12
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:10:24 CEST 2017

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