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GPR137 (G protein-coupled receptor 137)

Identity

Alias (NCBI)C11orf4
GPR137A
TM7SF1L1
HGNC (Hugo) GPR137
HGNC Alias symbC11orf4
GPR137A
TM7SF1L1
LocusID (NCBI) 56834
Atlas_Id 55360
Location 11q13.1  [Link to chromosome band 11q13]
Location_base_pair Starts at 64285848 and ends at 64289494 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
GPR137 (11q13.1) / GPR137 (11q13.1)PAFAH1B2 (11q23.3) / GPR137 (11q13.1)USP32 (17q23.1) / GPR137 (11q13.1)
PAFAH1B2 11q23.3 / GPR137 11q13.1USP32 17q23.1 / GPR137 11q13.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)GPR137   24300
Cards
Entrez_Gene (NCBI)GPR137    G protein-coupled receptor 137
AliasesC11orf4; GPR137A; TM7SF1L1
GeneCards (Weizmann)GPR137
Ensembl hg19 (Hinxton)ENSG00000173264 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000173264 [Gene_View]  ENSG00000173264 [Sequence]  chr11:64285848-64289494 [Contig_View]  GPR137 [Vega]
ICGC DataPortalENSG00000173264
TCGA cBioPortalGPR137
AceView (NCBI)GPR137
Genatlas (Paris)GPR137
SOURCE (Princeton)GPR137
Genetics Home Reference (NIH)GPR137
Genomic and cartography
GoldenPath hg38 (UCSC)GPR137  -     chr11:64285848-64289494 +  11q13.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GPR137  -     11q13.1   [Description]    (hg19-Feb_2009)
GoldenPathGPR137 - 11q13.1 [CytoView hg19]  GPR137 - 11q13.1 [CytoView hg38]
ImmunoBaseENSG00000173264
Genome Data Viewer NCBIGPR137 [Mapview hg19]  
Gene and transcription
Genbank (Entrez)AJ250392 AK056094 AK300209 AK302256 BC020396
RefSeq transcript (Entrez)NM_001170726 NM_001170880 NM_001170881 NM_001177358 NM_001378076 NM_001378077 NM_001378078 NM_001378079 NM_001378080 NM_001378081 NM_001378082 NM_001378083 NM_001378084 NM_001378085 NM_001378086 NM_001378087 NM_001378088 NM_001378089 NM_020155
Consensus coding sequences : CCDS (NCBI)GPR137
Gene ExpressionGPR137 [ NCBI-GEO ]   GPR137 [ EBI - ARRAY_EXPRESS ]   GPR137 [ SEEK ]   GPR137 [ MEM ]
Gene Expression Viewer (FireBrowse)GPR137 [ Firebrowse - Broad ]
GenevisibleExpression of GPR137 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)56834
GTEX Portal (Tissue expression)GPR137
Human Protein AtlasENSG00000173264-GPR137 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96N19   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96N19  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96N19
PhosPhoSitePlusQ96N19
Domains : Interpro (EBI)GPR137   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)GPR137
SuperfamilyQ96N19
AlphaFold pdb e-kbQ96N19   
Human Protein Atlas [tissue]ENSG00000173264-GPR137 [tissue]
HPRD12600
Protein Interaction databases
DIP (DOE-UCLA)Q96N19
IntAct (EBI)Q96N19
BioGRIDGPR137
STRING (EMBL)GPR137
ZODIACGPR137
Ontologies - Pathways
QuickGOQ96N19
Ontology : AmiGOlysosomal membrane  lysosomal membrane  autophagy  regulation of autophagy  integral component of membrane  negative regulation of osteoclast differentiation  negative regulation of bone resorption  positive regulation of TORC1 signaling  
Ontology : EGO-EBIlysosomal membrane  lysosomal membrane  autophagy  regulation of autophagy  integral component of membrane  negative regulation of osteoclast differentiation  negative regulation of bone resorption  positive regulation of TORC1 signaling  
NDEx NetworkGPR137
Atlas of Cancer Signalling NetworkGPR137
Wikipedia pathwaysGPR137
Orthology - Evolution
OrthoDB56834
GeneTree (enSembl)ENSG00000173264
Phylogenetic Trees/Animal Genes : TreeFamGPR137
Homologs : HomoloGeneGPR137
Homology/Alignments : Family Browser (UCSC)GPR137
Gene fusions - Rearrangements
Fusion : MitelmanPAFAH1B2/GPR137 [11q23.3/11q13.1]  
Fusion : MitelmanUSP32/GPR137 [17q23.1/11q13.1]  
Fusion : QuiverGPR137
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGPR137 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GPR137
dbVarGPR137
ClinVarGPR137
MonarchGPR137
1000_GenomesGPR137 
Exome Variant ServerGPR137
GNOMAD BrowserENSG00000173264
Varsome BrowserGPR137
ACMGGPR137 variants
VarityQ96N19
Genomic Variants (DGV)GPR137 [DGVbeta]
DECIPHERGPR137 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGPR137 
Mutations
ICGC Data PortalGPR137 
TCGA Data PortalGPR137 
Broad Tumor PortalGPR137
OASIS PortalGPR137 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGPR137  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DGPR137
Mutations and Diseases : HGMDGPR137
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaGPR137
DgiDB (Drug Gene Interaction Database)GPR137
DoCM (Curated mutations)GPR137
CIViC (Clinical Interpretations of Variants in Cancer)GPR137
Cancer3DGPR137
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETGPR137
MedgenGPR137
Genetic Testing Registry GPR137
NextProtQ96N19 [Medical]
GENETestsGPR137
Target ValidationGPR137
Huge Navigator GPR137 [HugePedia]
ClinGenGPR137
Clinical trials, drugs, therapy
MyCancerGenomeGPR137
Protein Interactions : CTDGPR137
Pharm GKB GenePA143485482
PharosQ96N19
Clinical trialGPR137
Miscellaneous
canSAR (ICR)GPR137
HarmonizomeGPR137
DataMed IndexGPR137
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXGPR137
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:11:18 CEST 2021

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