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GPR137B (G protein-coupled receptor 137B)

Identity

Alias (NCBI)TM7SF1
HGNC (Hugo) GPR137B
HGNC Previous nameTM7SF1
HGNC Previous nametransmembrane 7 superfamily member 1 (upregulated in kidney)
LocusID (NCBI) 7107
Atlas_Id 63957
Location 1q42.3  [Link to chromosome band 1q42]
Location_base_pair Starts at 236142539 and ends at 236208907 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
GPR137B (1q42.3) / MFHAS1 (8p23.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)GPR137B   11862
Cards
Entrez_Gene (NCBI)GPR137B    G protein-coupled receptor 137B
AliasesTM7SF1
GeneCards (Weizmann)GPR137B
Ensembl hg19 (Hinxton)ENSG00000077585 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000077585 [Gene_View]  ENSG00000077585 [Sequence]  chr1:236142539-236208907 [Contig_View]  GPR137B [Vega]
ICGC DataPortalENSG00000077585
TCGA cBioPortalGPR137B
AceView (NCBI)GPR137B
Genatlas (Paris)GPR137B
SOURCE (Princeton)GPR137B
Genetics Home Reference (NIH)GPR137B
Genomic and cartography
GoldenPath hg38 (UCSC)GPR137B  -     chr1:236142539-236208907 +  1q42.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GPR137B  -     1q42.3   [Description]    (hg19-Feb_2009)
GoldenPathGPR137B - 1q42.3 [CytoView hg19]  GPR137B - 1q42.3 [CytoView hg38]
ImmunoBaseENSG00000077585
Genome Data Viewer NCBIGPR137B [Mapview hg19]  
OMIM604658   
Gene and transcription
Genbank (Entrez)AF027826 AI634648 AK223632 AK295408 AK301552
RefSeq transcript (Entrez)NM_003272
Consensus coding sequences : CCDS (NCBI)GPR137B
Gene ExpressionGPR137B [ NCBI-GEO ]   GPR137B [ EBI - ARRAY_EXPRESS ]   GPR137B [ SEEK ]   GPR137B [ MEM ]
Gene Expression Viewer (FireBrowse)GPR137B [ Firebrowse - Broad ]
GenevisibleExpression of GPR137B in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7107
GTEX Portal (Tissue expression)GPR137B
Human Protein AtlasENSG00000077585-GPR137B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO60478   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO60478  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO60478
PhosPhoSitePlusO60478
Domains : Interpro (EBI)GPR137   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)GPR137B
SuperfamilyO60478
AlphaFold pdb e-kbO60478   
Human Protein Atlas [tissue]ENSG00000077585-GPR137B [tissue]
HPRD06878
Protein Interaction databases
DIP (DOE-UCLA)O60478
IntAct (EBI)O60478
BioGRIDGPR137B
STRING (EMBL)GPR137B
ZODIACGPR137B
Ontologies - Pathways
QuickGOO60478
Ontology : AmiGOprotein binding  lysosomal membrane  lysosomal membrane  integral component of plasma membrane  autophagy  regulation of autophagy  regulation of autophagy  membrane  regulation of macrophage activation  regulation of GTPase activity  negative regulation of osteoclast differentiation  negative regulation of osteoclast differentiation  negative regulation of bone resorption  negative regulation of bone resorption  positive regulation of protein localization to lysosome  positive regulation of TORC1 signaling  positive regulation of TORC1 signaling  
Ontology : EGO-EBIprotein binding  lysosomal membrane  lysosomal membrane  integral component of plasma membrane  autophagy  regulation of autophagy  regulation of autophagy  membrane  regulation of macrophage activation  regulation of GTPase activity  negative regulation of osteoclast differentiation  negative regulation of osteoclast differentiation  negative regulation of bone resorption  negative regulation of bone resorption  positive regulation of protein localization to lysosome  positive regulation of TORC1 signaling  positive regulation of TORC1 signaling  
NDEx NetworkGPR137B
Atlas of Cancer Signalling NetworkGPR137B
Wikipedia pathwaysGPR137B
Orthology - Evolution
OrthoDB7107
GeneTree (enSembl)ENSG00000077585
Phylogenetic Trees/Animal Genes : TreeFamGPR137B
Homologs : HomoloGeneGPR137B
Homology/Alignments : Family Browser (UCSC)GPR137B
Gene fusions - Rearrangements
Fusion : QuiverGPR137B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGPR137B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GPR137B
dbVarGPR137B
ClinVarGPR137B
MonarchGPR137B
1000_GenomesGPR137B 
Exome Variant ServerGPR137B
GNOMAD BrowserENSG00000077585
Varsome BrowserGPR137B
ACMGGPR137B variants
VarityO60478
Genomic Variants (DGV)GPR137B [DGVbeta]
DECIPHERGPR137B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGPR137B 
Mutations
ICGC Data PortalGPR137B 
TCGA Data PortalGPR137B 
Broad Tumor PortalGPR137B
OASIS PortalGPR137B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGPR137B  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DGPR137B
Mutations and Diseases : HGMDGPR137B
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaGPR137B
DgiDB (Drug Gene Interaction Database)GPR137B
DoCM (Curated mutations)GPR137B
CIViC (Clinical Interpretations of Variants in Cancer)GPR137B
Cancer3DGPR137B
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604658   
Orphanet
DisGeNETGPR137B
MedgenGPR137B
Genetic Testing Registry GPR137B
NextProtO60478 [Medical]
GENETestsGPR137B
Target ValidationGPR137B
Huge Navigator GPR137B [HugePedia]
ClinGenGPR137B
Clinical trials, drugs, therapy
MyCancerGenomeGPR137B
Protein Interactions : CTDGPR137B
Pharm GKB GenePA36563
PharosO60478
Clinical trialGPR137B
Miscellaneous
canSAR (ICR)GPR137B
HarmonizomeGPR137B
DataMed IndexGPR137B
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXGPR137B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:51:54 CEST 2021

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