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GPR139 (G protein-coupled receptor 139)

Identity

Alias_symbol (synonym)PGR3
Other aliasGPRg1
HGNC (Hugo) GPR139
LocusID (NCBI) 124274
Atlas_Id 63959
Location 16p12.3  [Link to chromosome band 16p12]
Location_base_pair Starts at 20031485 and ends at 20073778 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GPR139   19995
Cards
Entrez_Gene (NCBI)GPR139  124274  G protein-coupled receptor 139
AliasesGPRg1; PGR3
GeneCards (Weizmann)GPR139
Ensembl hg19 (Hinxton)ENSG00000180269 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000180269 [Gene_View]  ENSG00000180269 [Sequence]  chr16:20031485-20073778 [Contig_View]  GPR139 [Vega]
ICGC DataPortalENSG00000180269
TCGA cBioPortalGPR139
AceView (NCBI)GPR139
Genatlas (Paris)GPR139
WikiGenes124274
SOURCE (Princeton)GPR139
Genetics Home Reference (NIH)GPR139
Genomic and cartography
GoldenPath hg38 (UCSC)GPR139  -     chr16:20031485-20073778 -  16p12.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GPR139  -     16p12.3   [Description]    (hg19-Feb_2009)
GoldenPathGPR139 - 16p12.3 [CytoView hg19]  GPR139 - 16p12.3 [CytoView hg38]
ImmunoBaseENSG00000180269
Mapping of homologs : NCBIGPR139 [Mapview hg19]  GPR139 [Mapview hg38]
OMIM618448   
Gene and transcription
Genbank (Entrez)AB196529 AK291384 AY255545 AY635179 BC137237
RefSeq transcript (Entrez)NM_001002911 NM_001318483
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GPR139
Cluster EST : UnigeneHs.446875 [ NCBI ]
CGAP (NCI)Hs.446875
Alternative Splicing GalleryENSG00000180269
Gene ExpressionGPR139 [ NCBI-GEO ]   GPR139 [ EBI - ARRAY_EXPRESS ]   GPR139 [ SEEK ]   GPR139 [ MEM ]
Gene Expression Viewer (FireBrowse)GPR139 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)124274
GTEX Portal (Tissue expression)GPR139
Human Protein AtlasENSG00000180269-GPR139 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6DWJ6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6DWJ6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6DWJ6
Splice isoforms : SwissVarQ6DWJ6
PhosPhoSitePlusQ6DWJ6
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)GPCR_Rhodpsn    GPCR_Rhodpsn_7TM    GPR139   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)GPR139
DMDM Disease mutations124274
Blocks (Seattle)GPR139
SuperfamilyQ6DWJ6
Human Protein Atlas [tissue]ENSG00000180269-GPR139 [tissue]
Peptide AtlasQ6DWJ6
HPRD17062
IPIIPI00455139   
Protein Interaction databases
DIP (DOE-UCLA)Q6DWJ6
IntAct (EBI)Q6DWJ6
FunCoupENSG00000180269
BioGRIDGPR139
STRING (EMBL)GPR139
ZODIACGPR139
Ontologies - Pathways
QuickGOQ6DWJ6
Ontology : AmiGOplasma membrane  G protein-coupled receptor signaling pathway  phospholipase C-activating G protein-coupled receptor signaling pathway  neuropeptide signaling pathway  neuropeptide receptor activity  integral component of membrane  protein dimerization activity  
Ontology : EGO-EBIplasma membrane  G protein-coupled receptor signaling pathway  phospholipase C-activating G protein-coupled receptor signaling pathway  neuropeptide signaling pathway  neuropeptide receptor activity  integral component of membrane  protein dimerization activity  
NDEx NetworkGPR139
Atlas of Cancer Signalling NetworkGPR139
Wikipedia pathwaysGPR139
Orthology - Evolution
OrthoDB124274
GeneTree (enSembl)ENSG00000180269
Phylogenetic Trees/Animal Genes : TreeFamGPR139
HOGENOMQ6DWJ6
Homologs : HomoloGeneGPR139
Homology/Alignments : Family Browser (UCSC)GPR139
Gene fusions - Rearrangements
Fusion : QuiverGPR139
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGPR139 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GPR139
dbVarGPR139
ClinVarGPR139
1000_GenomesGPR139 
Exome Variant ServerGPR139
ExAC (Exome Aggregation Consortium)ENSG00000180269
GNOMAD BrowserENSG00000180269
Varsome BrowserGPR139
Genetic variants : HAPMAP124274
Genomic Variants (DGV)GPR139 [DGVbeta]
DECIPHERGPR139 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGPR139 
Mutations
ICGC Data PortalGPR139 
TCGA Data PortalGPR139 
Broad Tumor PortalGPR139
OASIS PortalGPR139 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGPR139  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DGPR139
Mutations and Diseases : HGMDGPR139
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GPR139
DgiDB (Drug Gene Interaction Database)GPR139
DoCM (Curated mutations)GPR139 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GPR139 (select a term)
intoGenGPR139
Cancer3DGPR139(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM618448   
Orphanet
DisGeNETGPR139
MedgenGPR139
Genetic Testing Registry GPR139
NextProtQ6DWJ6 [Medical]
TSGene124274
GENETestsGPR139
Target ValidationGPR139
Huge Navigator GPR139 [HugePedia]
snp3D : Map Gene to Disease124274
BioCentury BCIQGPR139
ClinGenGPR139
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD124274
Chemical/Pharm GKB GenePA134970866
Clinical trialGPR139
Miscellaneous
canSAR (ICR)GPR139 (select the gene name)
DataMed IndexGPR139
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGPR139
EVEXGPR139
GoPubMedGPR139
iHOPGPR139
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Sep 3 15:30:07 CEST 2019

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