Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

GPR143 (G protein-coupled receptor 143)

Identity

Alias (NCBI)NYS6
OA1
HGNC (Hugo) GPR143
HGNC Alias nameocular albinism 1
HGNC Previous nameOA1
HGNC Previous nameocular albinism 1 (Nettleship-Falls)
LocusID (NCBI) 4935
Atlas_Id 45630
Location Xp22.2  [Link to chromosome band Xp22]
Location_base_pair Starts at 9725346 and ends at 9765847 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
IFT27 (22q12.3)::GPR143 (Xp22.2)LOC100507412 (-)::GPR143 (Xp22.2)TBL1X (Xp22.31)::GPR143 (Xp22.2)
TBL1X Xp22.31::GPR143 Xp22.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)GPR143   20145
Cards
Entrez_Gene (NCBI)GPR143    G protein-coupled receptor 143
AliasesNYS6; OA1
GeneCards (Weizmann)GPR143
Ensembl hg19 (Hinxton)ENSG00000101850 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000101850 [Gene_View]  ENSG00000101850 [Sequence]  chrX:9725346-9765847 [Contig_View]  GPR143 [Vega]
ICGC DataPortalENSG00000101850
TCGA cBioPortalGPR143
AceView (NCBI)GPR143
Genatlas (Paris)GPR143
SOURCE (Princeton)GPR143
Genetics Home Reference (NIH)GPR143
Genomic and cartography
GoldenPath hg38 (UCSC)GPR143  -     chrX:9725346-9765847 -  Xp22.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GPR143  -     Xp22.2   [Description]    (hg19-Feb_2009)
GoldenPathGPR143 - Xp22.2 [CytoView hg19]  GPR143 - Xp22.2 [CytoView hg38]
ImmunoBaseENSG00000101850
Genome Data Viewer NCBIGPR143 [Mapview hg19]  
OMIM300500   300808   300814   
Gene and transcription
Genbank (Entrez)BC015657 BC068977 BU188283 Z48804
RefSeq transcript (Entrez)NM_000273
Consensus coding sequences : CCDS (NCBI)GPR143
Gene ExpressionGPR143 [ NCBI-GEO ]   GPR143 [ EBI - ARRAY_EXPRESS ]   GPR143 [ SEEK ]   GPR143 [ MEM ]
Gene Expression Viewer (FireBrowse)GPR143 [ Firebrowse - Broad ]
GenevisibleExpression of GPR143 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4935
GTEX Portal (Tissue expression)GPR143
Human Protein AtlasENSG00000101850-GPR143 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP51810   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP51810  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP51810
PhosPhoSitePlusP51810
Domains : Interpro (EBI)GPR143   
Domain families : Pfam (Sanger)Ocular_alb (PF02101)   
Domain families : Pfam (NCBI)pfam02101   
Conserved Domain (NCBI)GPR143
SuperfamilyP51810
AlphaFold pdb e-kbP51810   
Human Protein Atlas [tissue]ENSG00000101850-GPR143 [tissue]
HPRD02355
Protein Interaction databases
DIP (DOE-UCLA)P51810
IntAct (EBI)P51810
BioGRIDGPR143
STRING (EMBL)GPR143
ZODIACGPR143
Ontologies - Pathways
QuickGOP51810
Ontology : AmiGOG protein-coupled receptor activity  protein binding  cytoplasm  lysosomal membrane  Golgi apparatus  plasma membrane  plasma membrane  plasma membrane  eye pigment biosynthetic process  signal transduction  G protein-coupled receptor signaling pathway  G protein-coupled receptor signaling pathway  G protein-coupled receptor signaling pathway  G protein-coupled receptor signaling pathway  neuropeptide signaling pathway  visual perception  membrane  integral component of membrane  apical plasma membrane  melanosome localization  melanosome transport  melanosome organization  melanosome organization  melanosome membrane  melanosome membrane  dopamine binding  dopamine binding  calcium-mediated signaling using intracellular calcium source  L-DOPA receptor activity  L-DOPA receptor activity  melanosome  phosphatidylinositol-mediated signaling  regulation of calcium-mediated signaling  regulation of calcium-mediated signaling  L-DOPA binding  L-DOPA binding  tyrosine binding  tyrosine binding  
Ontology : EGO-EBIG protein-coupled receptor activity  protein binding  cytoplasm  lysosomal membrane  Golgi apparatus  plasma membrane  plasma membrane  plasma membrane  eye pigment biosynthetic process  signal transduction  G protein-coupled receptor signaling pathway  G protein-coupled receptor signaling pathway  G protein-coupled receptor signaling pathway  G protein-coupled receptor signaling pathway  neuropeptide signaling pathway  visual perception  membrane  integral component of membrane  apical plasma membrane  melanosome localization  melanosome transport  melanosome organization  melanosome organization  melanosome membrane  melanosome membrane  dopamine binding  dopamine binding  calcium-mediated signaling using intracellular calcium source  L-DOPA receptor activity  L-DOPA receptor activity  melanosome  phosphatidylinositol-mediated signaling  regulation of calcium-mediated signaling  regulation of calcium-mediated signaling  L-DOPA binding  L-DOPA binding  tyrosine binding  tyrosine binding  
NDEx NetworkGPR143
Atlas of Cancer Signalling NetworkGPR143
Wikipedia pathwaysGPR143
Orthology - Evolution
OrthoDB4935
GeneTree (enSembl)ENSG00000101850
Phylogenetic Trees/Animal Genes : TreeFamGPR143
Homologs : HomoloGeneGPR143
Homology/Alignments : Family Browser (UCSC)GPR143
Gene fusions - Rearrangements
Fusion : MitelmanTBL1X::GPR143 [Xp22.31/Xp22.2]  
Fusion : QuiverGPR143
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGPR143 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GPR143
dbVarGPR143
ClinVarGPR143
MonarchGPR143
1000_GenomesGPR143 
Exome Variant ServerGPR143
GNOMAD BrowserENSG00000101850
Varsome BrowserGPR143
ACMGGPR143 variants
VarityP51810
Genomic Variants (DGV)GPR143 [DGVbeta]
DECIPHERGPR143 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGPR143 
Mutations
ICGC Data PortalGPR143 
TCGA Data PortalGPR143 
Broad Tumor PortalGPR143
OASIS PortalGPR143 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGPR143  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DGPR143
Mutations and Diseases : HGMDGPR143
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaGPR143
DgiDB (Drug Gene Interaction Database)GPR143
DoCM (Curated mutations)GPR143
CIViC (Clinical Interpretations of Variants in Cancer)GPR143
Cancer3DGPR143
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300500    300808    300814   
Orphanet629   
DisGeNETGPR143
MedgenGPR143
Genetic Testing Registry GPR143
NextProtP51810 [Medical]
GENETestsGPR143
Target ValidationGPR143
Huge Navigator GPR143 [HugePedia]
ClinGenGPR143
Clinical trials, drugs, therapy
MyCancerGenomeGPR143
Protein Interactions : CTDGPR143
Pharm GKB GenePA31872
PharosP51810
Clinical trialGPR143
Miscellaneous
canSAR (ICR)GPR143
HarmonizomeGPR143
ARCHS4GPR143
DataMed IndexGPR143
Probes
Litterature
PubMed66 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXGPR143
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sun Jan 16 18:12:57 CET 2022

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.